| DRUG | DRUG DESCRIPTION |
|---|---|
| Acebutolol | A selective β1-receptor antagonist used for the management of hypertension and ventricular premature beats in adults. |
| Acecainide | Acecainide is an investigational anti-arrhythmia drug. |
| Acetazolamide | A carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma. |
| Acetylcholine | A parasympathomimetic neurotransmitter used to induce miosis of the iris in seconds after delivery of the lens in cataract surgery, in penetrating keratoplasty, iridectomy and other anterior segment surgery where rapid miosis may be required. |
| Acetyldigitoxin | Used for fast digitalization in congestive heart failure. |
| Acetyldigoxin | Not Annotated |
| Acetylsalicylic acid | A salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events. |
| Adenosine | A medication used in myocardial perfusion scintigraphy and to treat supraventricular tachycardia. |
| Adrenalone | Not Annotated |
| Ajmaline | An antiarrhythmic used to manage a variety of forms of tachycardias. |
| Alprenolol | For the treatment of hypertension, angina, and arrhythmia |
| Alprostadil | A prostaglandin E1 agonist used for the treatment of erectile dysfunction and as an adjunct for its diagnosis. |
| Alteplase | A recombinant form of human tissue plasminogen activator used in the emergency treatment of myocardial infarction, ischemic stroke, and pulmonary emboli. |
| Ambrisentan | A selective type A endothelin receptor antagonist used to treat primary pulmonary arterial hypertension and pulmonary arterial hypertension based on diagnostic classifications. |
| Amiloride | A pyrizine compound used to treat hypertension and congestive heart failure. |
| Aminophylline | A bronchodilator consisting of theophylline that is used for the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis. |
| Amiodarone | A class III antiarrhythmic indicated for the treatment of recurrent hemodynamically unstable ventricular tachycardia and recurrent ventricular fibrillation. |
| Amlodipine | A calcium channel blocker used to treat hypertension and angina. |
| Amrinone | A positive inotropic agent and phosphodiesterase inhibitor used in the management of treatment of congestive heart failure. |
| Amyl Nitrite | A fast acting vasodilator used for rapid relief of angina pectoris. |
| Anagrelide | A platelet-reducing agent used to treat thrombocythemia, and its related complications, secondary to myeloproliferative neoplasms. |
| Ancrod | An anticoagulant purified from the venom of the Malayan pit viper that functions by inactivating circulating plasma fibrinogen. Not currently approved for use or marketed in any country. |
| Angiotensin 1-7 | TXA127 has been investigated for the treatment of Miscellaneous Peripheral Blood Cell Abnormalities. |
| Angiotensin II | A peptide hormone of the RAAS system used to raise blood pressure in septic or other forms of shock. |
| Angiotensinamide | Not Annotated |
| Anisodamine | Anisodamine has been investigated for the treatment of Intestinal Diseases. |
| Anistreplase | A form of recombinant human tissue plasminogen activator used in the emergency treatment of myocardial infarction and pulmonary emboli. |
| Apinocaltamide | Apinocaltamide is under investigation in clinical trial NCT03239691 (A Study to Evaluate the Effect of ACT-709478 in Photosensitive Epilepsy Patients). |
| Aprindine | Aprindine is a cardiac depressant used in arrhythmias. |
| AR-9281 | Investigated for use/treatment in hypertension. |
| Arbutamine | Used to elicit acute cardiovascular responses (cardiac stumulant), similar to those produced by exercise, in order to aid in diagnosing the presence or absence of coronary artery disease (CAD) in… |
| Ardeparin | For prevention of deep vein thrombosis, which may result in pulmonary embolism, following knee surgery. |
| Atenolol | A synthetic beta-1 selective blocker used in the management of hypertension and chronic angina, and to reduce mortality in known or suspected myocardial infarction in hemodynamically stable patients. |
| Atrial natriuretic peptide | Not Annotated |
| Atropine | A muscarinic antagonist used to treat poisoning by muscarinic agents, including organophosphates and other drugs. |
| Azimilide | Investigated for use/treatment in arrhythmia and atrial fibrillation. |
| Bamethan | Not Annotated |
| Bamifylline | A methylxanthine derivative indicated in the treatment of bronchial asthma and other conditions with bronchospasm. |
| Barnidipine | A calcium channel blocker used to treat various forms of hypertension. |
| Batroxobin | No approved indications. Batroxobin is a defibrongenating agent which has been observed to reduce fibrinogen levels and thus reduce clot risk when used intravenously. |
| Benazepril | An ACE inhibitor prodrug used to treat hypertension. |
| Benazeprilat | Not Annotated |
| Bencyclane | A vasodilator agent found to be effective in a variety of peripheral circulation disorders. It has various other potentially useful pharmacological effects. Its mechanism may involve block of calcium channels. |
| Bendroflumethiazide | A diuretic used to suppress lactation and to treat hypertension and edema. |
| Benidipine | A synthetic dihydropyridine calcium channel blocker used to treat hypertension and angina pectoris. |
| Bepridil | For the treatment of hypertension, and chronic stable angina (classic effort-associated angina). |
| Beraprost | For the treatment of pulmonary hypertension. |
| Berbamine | Not Annotated |
| beta-Escin | An anti-inflammatory and vasoconstrictive agent indicated to treat minor muscle and joint trauma. |
| beta-Isosparteine | Not Annotated |
| Betaxolol | A cardioselective beta blocking agent commonly used to treat hypertension and elevated intraocular pressure (when administered ophthalmically). |
| Bethanidine | For the treatment of hypertension. |
| Bietaserpine | Not Annotated |
| Bimatoprost | A prostaglandin analog used to treat hypotrichosis of the eyelashes and intraocular pressure in open angle glaucoma or ocular hypertension. |
| Bisoprolol | A beta-1 adrenergic blocking agent used to prevent myocardial infarction and heart failure and to treat mild to moderate hypertension. |
| BMS-813160 | BMS-813160 is under investigation in clinical trial NCT03496662 (BMS-813160 With Nivolumab and Gemcitabine and Nab-paclitaxel in Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma (PDAC)). |
| Bosentan | A dual endothelin receptor antagonist used to treat pulmonary arterial hypertension. |
| BQ-123 | BQ-123 has been investigated for the basic science and treatment of Coronary Artery Disease, Aorto-coronary Bypass Grafting, and ST-Elevation Myocardial Infarction. |
| BQ-788 | Not Annotated |
| Bradykinin | Bradykinin has been investigated for the basic science and treatment of Hypertension and Diabetes Type 2. |
| Bretylium | A norepinephrine release inhibitor used for the prophylaxis and therapy of ventricular fibrillation, as well as the treatment of life-threatening ventricular arrhythmias. |
| Brimonidine | An alpha-2 adrenergic agonist used to treat glaucoma and ocular hypertension, as well as facial erythema in rosacea. |
| Brinase | Not Annotated |
| Bucindolol | Bucindolol has been investigated in Heart Failure. |
| Buflomedil | Not Annotated |
| Bufylline | Not Annotated |
| Bumetanide | A sulfamyl diuretic used to treat edema in congestive heart failure, hepatic and renal disease, and nephrotic syndrome. |
| Bunaftine | Not Annotated |
| Bupranolol | Used to manage hypertension and tachycardia. Also used to treat glaucoma. |
| Butalamine | Not Annotated |
| Buthiazide | A diuretic indicated in the treatment of edema caused by congestive heart failure, as well as hepatic and renal diseases. |
| Cadralazine | Not Annotated |
| Cafedrine | Cafedrine is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation). |
| Calcitonin gene-related peptide | Investigated for use/treatment in myocardial infarction, heart disease, and asthma. |
| Calyculin A | Not Available |
| Candesartan | An angiotensin-receptor blocker indicated in the treatment of hypertension. |
| Candesartan cilexetil | An angiotensin receptor blocker used to treat hypertension, systolic hypertension, left ventricular hypertrophy, and delay progression of diabetic nephropathy. |
| Candoxatril | Candoxatril is the orally-active prodrug of candoxatrilat (UK-73967), a potent neutral endopeptidase (NEP) inhibitor. |
| Canertinib | Investigated for use/treatment in breast cancer and lung cancer. |
| Captopril | An ACE inhibitor used for the management of essential or renovascular hypertension, congestive heart failure, left ventricular dysfunction following myocardial infarction, and nephropathy. |
| Carbamazepine | An anticonvulsant used to treat various types of seizures and pain resulting from trigeminal neuralgia. |
| Carbamoylcholine | A direct acting miotic agent administered ophthalmically to decrease intraocular pressure after cataract surgery, and to induce miosis during surgery. |
| Carbocromen | Carbocromen was marketed for use in Germany as a vasodilator, however, it has been discontinued due to the risk of arrhythmia development . |
| Carboxyamidotriazole | Carboxyamidotriazole has been used in trials studying the treatment of Lymphoma, Lung Cancer, Breast Cancer, Kidney Cancer, and Ovarian Cancer, among others. |
| Cariporide | Investigated for use/treatment in cardiac surgery. |
| Caroverine | A calcium channel blocker indicated in the treatment of smooth muscle spasms, alcohol and drug withdrawal, and tinnitus. |
| Carteolol | A beta adrenergic antagonist used to treat arrhythmia, angina, hypertension, and glaucoma. |
| Carvedilol | A non selective beta-adrenergic antagonist used to treat mild to severe chronic heart failure, hypertension, and left ventricular dysfunction following myocardial infarction in clinically stable patients. |
| Celiprolol | A beta-blocker for the management of hypertension and angina pectoris. |
| Cetiedil | Not Annotated |
| Chlorothiazide | A thiazide diuretic used to treat hypertension and edema in congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. |
| Chlorthalidone | A diuretic used to treat hypertension or edema caused by heart failure, renal failure, hepatic cirrhosis, estrogen therapy, and other conditions. |
| Cibenzoline | Not Annotated |
| Cicletanine | Cicletanine is under investigation for the treatment of Diabetes, Hypokalemia, Hyponatremia, and Arterial Hypertension. |
| Cilazapril | An ACE inhibitor used for the management of hypertension and heart failure. |
| Cilazaprilat | Not Annotated |
| Cilnidipine | A dihydropyridine calcium channel blocker with action on both N- and L-type calcium channels used to treat hypertension. |
| Cilostazol | An antiplatelet agent and vasodilator used for the symptomatic relief of intermittent claudication. |
| Cinepazide | Cinepazide has been used in trials studying the treatment of Ischemic Stroke. |
| Cinnamic acid | Not Annotated |
| Cinnarizine | A drug used for the management of labyrinthine disorder symptoms, including vertigo, tinnitus, nystagmus, nausea, and vomiting. |
| Cirazoline | Cirazoline acts on a number of α adrenergic receptors. It is an agonist of α1A, partial agonist of α1B and α1D, and a nonselective antagonist of α2. It is believed… |
| Clevidipine | A dihydropyridine L-type calcium channel blocker used to lower blood pressure when oral antihypertensive therapy is not feasible or not desirable. |
| Clonidine | An alpha-2 adrenergic agonist used to treat hypertension and severe cancer pain, among other conditions, and to treat withdrawal symptoms from various substances. It is also used to aid in the diagnosis of pheochromocytoma and to prevent migraines. |
| Cloranolol | Not Annotated |
| Cocaine | An ester local anesthetic used during diagnostic procedures and surgeries in or through the nasal cavities. |
| Colforsin | Potent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant Coleus forskohlii. Has antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities;… |
| Cryptenamine | For the treatment of hypertension. |
| Cyclandelate | A vasodilator used for the treatment of various blood vessel diseases, such as claudication and arteriosclerosis. |
| Cyclopenthiazide | Cyclopenthiazide is a thiazide diuretic with antihypertensive properties. In a double blind, randomized crossover study, cyclopenthiazide was effective in reducing diastolic blood pressure in mildly hypertensive non-insulin dependent diabetic patients… |
| Cyclothiazide | Cyclothiazide is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. It is also indicated in the management of hypertension either… |
| Cymarin | Not Annotated |
| Dalfampridine | A potassium channel blocker used for the improvement of motor function in patients with multiple sclerosis (MS). |
| Dalteparin | A low molecular weight heparin used for the prophylaxis of thrombotic events in certain patients and prevent acute cardiac ischemic events in patients with unstable angina and non-Q-wave myocardial infarction. |
| Danaparoid | A heparinoid with anticoagulant and antithrombotic activities used for the treatment of acute episode of Heparin-Induced Thrombocytopenia (HIT), and for prophylaxis in patients with a history of HIT. |
| Darodipine | Darodipine is a calcium channel blocker. |
| Debrisoquine | For the treatment of moderate and severe hypertension, either alone or as an adjunct, and for the treatment of renal hypertension. |
| Defibrotide | A mixture of single-stranded oligonucleotides used in the treatment of severe hepatic veno-occlusive disease with renal or pulmonary dysfunction following hematopoietic stem-cell transplantation. |
| Delapril | An ACE inhibitor indicated in the treatment of essential hypertension. |
| Desirudin | Indicated as prophylaxis of deep vein thrombosis for patients undergoing hip replacement surgery. |
| Deslanoside | For the treatment and management of Congestive cardiac insufficiency, arrhythmias and heart failure. |
| Desmopressin | A synthetic analog of vasopressin used to reduce renal excretion of water in central diabetes insipidus and nocturia. |
| Desmoteplase | Investigated for use/treatment in cerebral ischemia and strokes. |
| Dexanabinol | Investigated for use/treatment in traumatic brain injuries and neurologic disorders. |
| Dexpropranolol | Not Available |
| Dexrazoxane | A cytoprotective drug used to prevent and improve cardiomyopathy associated with doxorubicin treatment for metastatic breast cancer. |
| Dexverapamil | Not Annotated |
| Diazoxide | A non diuretic benzothiadiazine indicated for the management of hypoglycemia in patients who produce an excess of insulin caused by a variety of conditions. |
| Dideoxyadenosine | Not Annotated |
| Diethylnorspermine | Investigated for use/treatment in renal cell carcinoma, pancreatic cancer, melanoma, and lung cancer. |
| Digitoxin | A cardiac glycoside used in the treatment and management of congestive cardiac insufficiency, arrhythmias and heart failure. |
| Digoxin | A cardiac glycoside used in the treatment of mild to moderate heart failure and for ventricular response rate control in chronic atrial fibrillation. |
| Dihydralazine | Dihydralazine is under investigation in clinical trial NCT00311974 (The Effect of Dihydralazine on Kidney Function and Hormones in Healthy Individuals). |
| Dihydroergocristine | An ergot alkaloid used to delay progressive mental decline in conditions like Alzheimer’s. |
| Dihydroergocryptine | A dopamine agonist indicated in the treatment of cerebrovascular diseases and atherosclerosis. |
| Dihydroergotamine | An ergot alkaloid used in the acute treatment of migraine headache and cluster headache. |
| Dilazep | Not Annotated |
| Diltiazem | A calcium channel blocker used to treat hypertension and to manage chronic stable angina. |
| Dipyridamole | A phosphodiesterase inhibitor used to prevent postoperative thromboembolic events. |
| Disopyramide | A class 1A antiarrhythmic agent used to treat life-threatening ventricular arrhythmias. |
| Disufenton | Not Annotated |
| Dobutamine | A beta-1 agonist used to treat cardiac decompensation in patients with organic heart disease or from cardiac surgery. |
| Dofetilide | A class III antiarrhythmic drug used for the maintenance of normal sinus rhythm and cardioversion in cases of atrial fibrillation and atrial flutter. |
| Dopamine | A catecholamine neurotransmitter used to treat hemodynamic imbalances, poor perfusion of vital organs, low cardiac output, and hypotension. |
| Dopexamine | Dopexamine has been used in trials studying the diagnostic and treatment of Free Flap, Oral Cancer, Hypotension, Septic Shock, and Head and Neck Cancer. |
| Dorzolamide | A carbonic anhydrase inhibitor used to treat high intraocular pressure in ocular hypertension and open angle glaucoma. |
| Dotarizine | A calcium antagonist used to treat and prevent migraines. |
| Doxazosin | An alpha-1 adrenergic receptor used to treat mild to moderate hypertension and urinary obstruction due to benign prostatic hyperplasia. |
| Dronedarone | An antiarrhythmic agent used in the reduce the risk of hospitalization in patients with paroxysmal or persistent atrial fibrillation. |
| Drotaverine | A phosphodiesterase-4 inhibitor used to alleviate gastrointestinal and genitourinary smooth muscle spasms. |
| Dyphylline | A theophylline derivative used to treat asthma, bronchospasm, and COPD. |
| Efonidipine | For the treatment of hypertension. |
| Emopamil | Prevents renal injury after warm & cold ischemia. |
| Enadoline | Not Annotated |
| Enalapril | A prodrug of an ACE inhibitor used to treat hypertension and congestive heart failure. |
| Enalaprilat | An antihypertensive agent used for the management of hypertension when oral therapy is not practical. |
| Encainide | A voltage-gated sodium channel blocker used for management of atrial or ventricular fibrillation, atrial flutter, and ventricular tachycardia, that is no longer used due to proarrhythmic adverse effects. |
| Endralazine | Not Annotated |
| Enoxaparin | A low molecular weight heparin used for the prophylaxis of deep vein thrombosis and ischemic complications of unstable angina and non-Q-wave myocardial infarction. |
| Enoximone | A selective phosphodiesterase inhibitor indicated in the short term treatment of congestive heart failure. |
| Epanolol | Epanolol is an beta blocker. |
| Eperisone | An antispasmodic that functions through voltage-gated channel blockade, notably with little to no sedation, effective in relaxing skeletal muscles and vascular smooth muscles. |
| Ephedrine | An alpha and beta-adrenergic agonist indicated to treat hypotension under anesthesia, allergic conditions, bronchial asthma, and nasal congestion. |
| Epicaptopril | Not Available |
| Epinephrine | A hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma. |
| Eplerenone | An aldosterone receptor antagonist used to improve survival of patients with symptomatic heart failure and to reduce blood pressure. |
| Eplivanserin | Eplivanserin has been used in trials studying the treatment of Sleep, Insomnia, Chronic Pain, Fibromyalgia, and Primary Insomnia, among others. |
| Epoprostenol | A vasodilator and platelet aggregation inhibitor used for the management of primary pulmonary hypertension and pulmonary hypertension in patients with heart failure. |
| Eprosartan | An ARB used to treat hypertension, diabetic nephropathy, and congestive heart failure. |
| Ergoloid mesylate | A nootropic with an unknown mechanism of action indicated in individuals over sixty who manifest signs and symptoms of an idiopathic decline in mental capacity. |
| Ergotamine | An alpha-1 selective adrenergic agonist vasoconstrictor used to treat migraines with or without aura and cluster headaches. |
| Erythritol | Erythritol is a four-carbon sugar that is found in algae, fungi, and lichens. It is twice as sweet as sucrose and can be used as a coronary vasodilator. |
| Erythrityl tetranitrate | For the prevention of angina. |
| Escin | An anti-inflammatory and vasoconstrictive agent indicated to treat minor muscle and joint trauma. |
| Eslicarbazepine | An antiepileptic indicated as a monotherapy or adjunct therapy in the treatment of epilepsy. |
| Eslicarbazepine acetate | An anticonvulsant agent used as an adjunct to treat partial-onset seizures in patients with inadequate clinical response to conventional antiepileptic therapy. |
| Etafenone | Etafenone is a vasodilator. |
| Ethacizine | Not Annotated |
| Ethanolamine oleate | A mild sclerosing agent used in the treatment of esophageal varices with recent bleeding episodes. |
| Ethotoin | A hydantoin antiepileptic used to control tonic-clonic and complex partial seizures. |
| Etilefrine | An adrenergic agonist primarily of α1 and β1 receptors used as an anti-hypotensive. |
| Etripamil | Etripamil has been used in trials studying the treatment of Paroxysmal Supraventricular Tachycardia (PSVT). |
| Fasudil | Fasudil has been investigated in Carotid Stenosis. |
| Felodipine | A calcium channel blocker used to treat hypertension. |
| Felypressin | For use as an alternative to adrenaline as a localising agent, provided that local ischaemia is not essential. |
| Fendiline | Fendiline is a coronary vasodilator which inhibits calcium function in muscle cells in excitation-contraction coupling. It has been proposed as an antiarrhythmic and antianginal agent. Fendiline is non-selective. |
| Fenoldopam | A dopamine D1 receptor agonist used for the short term management of hypertension. |
| Ferulic acid | Not Available |
| Fibrinolysin | Fibrinolysin assists with the healing of minor burns, superficial wounds, ulcers, surgical wounds, and superficial hematomas. |
| Flecainide | A class Ic antiarrhythmic agent used to manage atrial fibrillation and paroxysmal supraventricular tachycardias (PSVT). |
| Flosequinan | Flosequinan was approved in the USA and the UK for a year prior to being withdrawn from the market due to increased mortality in chronic heart failure patients, found in… |
| Flunarizine | A selective calcium-entry blocker used as migraine prophylaxis in patients with severe and frequent episodes who have not responded adequately to more common treatments. |
| Fondaparinux | An anticoagulant used to prevent venous thromboembolism, to treat deep vein thrombosis, and to improve survival following myocardial infarction. |
| Fosfructose | A phosphorylated form of fructose indicated in the treatment of hypophosphatemia. |
| Fosinopril | An ACE inhibitor used to treat mild to moderate hypertension, congestive heart failure, and to slow the progression of renal disease in hypertensive diabetics. |
| Fosinoprilat | Fosinoprilat is the active phosphinic acid metabolite of prodrug fosinopril, which is activated by esterases in vivo. It binds zinc with phosphinic acid group. |
| Fosphenytoin | An antiepileptic agent used for the management of generalized convulsive status epilepticus and prevention and treatment of seizures occurring during neurosurgery. |
| Furosemide | A loop diuretic used to treat hypertension and edema in congestive heart failure, liver cirrhosis, renal disease, and hypertension. |
| Gallopamil | Gallopamil has been used in trials studying the treatment of Asthma. |
| Ginkgo biloba | A herbal supplement found in over-the-counter or unapproved homeopathic products for various health conditions, such as cognitive, neurodegenerative, cardiovascular, and reproductive health disorders. |
| Glimepiride | A sulfonylurea drug used to treat type 2 diabetes mellitus. |
| Guanabenz | An alpha-2 adrenergic agonist used to treat hypertension. |
| Guanadrel | Used to treat and control hypertension. |
| Guanethidine | An antihypertensive agent used in the management of moderate and severe hypertension, either alone or as an adjunct, and for the management of renal hypertension. |
| Guanfacine | An alpha-2A adrenergic receptor agonist used to treat ADHD. |
| Heparin | An anticoagulant indicated for thromboprophylaxis and to treat thrombosis associated with a variety of conditions such as pulmonary embolism and atrial fibrillation. |
| Hexamethonium | A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been… |
| Hexobendine | Hexobendine is a medication used to cause vasodilation, to treat several conditions including angina pectoris. It has not been approved in the United States or the United Kingdom, but has… |
| Higenamine | Higenamine is under investigation in clinical trial NCT01451229 (Pharmacokinetics and Pharmacodynamics of Higenamine in Chinese Healthy Subjects). |
| Hydralazine | An antihypertensive agent used for the management of essential hypertension or severe hypertension associated with conditions requiring immediate action, heart failure, and pre-eclampsia or eclampsia . |
| Hydrochlorothiazide | A thiazide diuretic used to treat edema associated with a number of conditions, and hypertension. |
| Hydroflumethiazide | A thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure and liver cirrhosis. |
| Hydroquinidine | A medication indicated in the maintenance of a normal sinus rhythm, as well as the treatment and prevention of abnormal rhythm. |
| Hydroquinine | Not Annotated |
| Hyoscyamine | An anticholinergic indicated to treat functional gastrointestinal disorders, biliary and renal colic, and acute rhinitis. |
| Ibopamine | A sympathomimetic, indicated in the induction of mydriasis and treatment of pos-surgical ocular hypotonia. |
| Ibudilast | For the treatment of multiple sclerosis, asthma, and cerebrovascular disease. |
| Ibutilide | A class III antiarrhythmic agent used to correct atrial fibrillation and atrial flutter, which can be considered as an alternative to cardioversion. |
| Ifenprodil | N-methyl-D-aspartate (NMDA) receptors (NMDARs) are members of the ionotropic glutamate receptor family, with key roles in brain development and neurological function.[A220118, A220128] NMDARs are heterotetramers that typically involve a dimer… |
| Iloprost | A synthetic prostacyclin analog indicated to treat pulmonary arterial hypertension (PAH). |
| Imidapril | An ACE inhibitor used in the treatment of essential hypertension. |
| Imolamine | Imolamine is indicated for the treatment of angina pectoris. The hydrochloride form is used as a local anesthetic. |
| Indapamide | A thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure. |
| Indenolol | Indenolol is a drug of the beta-adrenergic blocker class. |
| Indomethacin | A nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants. |
| Indoramin | Indoramin is a discontinued piperidine antiadrenergic drug with the trade names Baratol and Doralese. It is a selective alpha-1 adrenergic antagonist with no reflex tachycardia and direct myocardial depression action. |
| Inositol nicotinate | A vasodilator and source of niacin found in dietary supplements. |
| Irbesartan | An angiotensin receptor blocker used to treat hypertension, delay progression of diabetic nephropathy, and treat congestive heart failure. |
| Isoprenaline | A catecholamine non-selective beta-adrenergic agonist typically used to treat bradycardia and heart block. |
| Isosorbide | A vasodilator used for the prevention and treatment of angina pectoris due to coronary artery disease. It was previously used to reduce intraocular pressure. |
| Isosorbide dinitrate | A vasodilator used to treat angina in coronary artery disease. |
| Isosorbide mononitrate | A nitrate used to prevent and treat angina and to treat angina caused by coronary artery disease. |
| Isoxsuprine | A beta-adrenergic agonist used in the symptomatic treatment of cerebrovascular insufficiency, peripheral vascular disease of arteriosclerosis obliterans, thromboangiitis obliterans (Buerger’s disease) and Raynaud’s disease. |
| Isradipine | A dihydropyridine calcium channel blocker used for the treatment of hypertension. |
| Ivabradine | A HCN channel blocker used to reduce the risk of hospitalization for worsening heart failure in adult patients and for treatment of stable symptomatic heart failure as a result of dilated cardiomyopathy in pediatric patients. |
| Ketanserin | Ketanserin has been investigated for the treatment of Septic Shock, Severe Sepsis, and Diabetic Foot Ulcer. |
| Labetalol | An alpha and beta adrenergic antagonist used to treat hypertension, angina, and sympathetic overactivity syndrome. |
| Lacidipine | A lipophilic dihydropyridine calcium channel blocker with a slow onset of action used to treat hypertension. |
| Lacosamide | An antiepileptic drug used to treat partial onset seizures in adults. |
| Landiolol | An ultra short-acting selective beta-blocker used for rapid ventricular rate control in cases of supraventricular tachycardia. |
| Lepirudin | A protein-based direct thrombin inhibitor used as an anticoagulant in patients with heparin-induced thrombocytopenia. |
| Lercanidipine | A calcium channel blocker for the management of hypertension. |
| Levonordefrin | A topical sympathomimetic amine found in local anesthetic products that is used for nasal decongestion or vasoconstriction during dental procedures. |
| Levosimendan | A calcium sensitizer indicated to treat acutely decompensated severe chronic heart failure. |
| Lidocaine | A local anesthetic used in a wide variety of superficial and invasive procedures. |
| Lidoflazine | Not Annotated |
| Linopirdine | Not Annotated |
| Linsidomine | Not Annotated |
| Lisinopril | An ACE inhibitor used to treat hypertension, heart failure, and acute myocardial infarction. |
| Lofexidine | A centrally acting alpha2-adrenergic agonist used for the symptomatic treatment of acute opioid withdrawal syndrome to facilitate abrupt opioid discontinuation in adults. |
| Lomerizine | Lomerizine is a diphenylmethylpiperazine calcium channel blocker[A245378, A245383] with relatively selective central nervous system (CNS) effects. This drug is used to prophylactically treat migraines[A245368, A245373] and is also being investigated… |
| Lorajmine | Not Annotated |
| Lorcainide | Not Annotated |
| Losartan | An angiotensin receptor blocker used to treat hypertension and diabetic nephropathy, and is used to reduce the risk of stroke. |
| Lypressin | Not Annotated |
| Magnesium sulfate | A drug used to treat convulsions during pregnancy, nephritis in children, magnesium deficiency, and tetany. |
| Manidipine | A dihydropyridine calcium channel blocker used to treat hypertension. |
| Mecamylamine | A nicotine antagonist used to treat moderate to severe essential hypertension and uncomplicated malignant hypertension. |
| Meldonium | Not Annotated |
| Mephentermine | A sympathomimetic agent used in the treatment of hypotension. |
| Metaraminol | For the treatment and prevention of hypotension due to hemorrhage, spinal anesthesia, and shock associated with brain damage |
| Methazolamide | A carbonic anhydrase inhibitor used to treat open angle glaucoma and acute angle closure glaucoma. |
| Methoxamine | An alpha adrenergic agonist used to treat hypotension. |
| Methyldopa | A centrally-acting alpha-2 adrenergic agonist used to manage hypertension alone or in combination with hydrochlorothiazide, and to treat hypertensive crises. |
| Methysergide | An ergot alkaloid used for the prophylaxis of migraine and cluster headaches. |
| Metildigoxin | A digitalis glycoside indicated in the treatment of acute and chronic heart failure. |
| Metipranolol | A beta-adrenergic antagonist used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. |
| Metolazone | A thiazide-like diuretic used to treat hypertension. |
| Metoprolol | A beta-blocker used in the treatment of hypertension and angina, and used to reduce mortality due to myocardial infarction. |
| Mexiletine | A class 1B antiarrhythmic agent used in the treatment of documented ventricular arrhythmias that warrant treatment. |
| Mibefradil | For the treatment of angina and high blood pressure. |
| Midodrine | An alpha-adrenergic agonist used to treat orthostatic hypotension. |
| Milrinone | A PDE-III inhibitor with inotropic, lusitropic, and vasodilatory properties used for the short-term treatment of acute decompensated heart failure. |
| Minoxidil | An antihypertensive vasodilating agent used for resistant hypertension that is symptomatic or has caused end organ damage. |
| Moexipril | An angiotensin converting enzyme inhibitor prodrug used to treat hypertension. |
| Molsidomine | A long-acting vasodilator used to treat angina pectoris, including in association with left heart failure and acute myocardial infarction. |
| Monteplase | Monteplase has been used in trials studying the treatment of Pulmonary Embolism. |
| Moricizine | An antiarrhythmic used to treat arrhythmias. |
| Morrhuic acid | Morrhuic acid is a mixture of unsaturated fatty acids obtained from cod liver oil. |
| Moxisylyte | By the WHO, moxisylyte is indicated for the symptomatic management of sequelae of cerebral infarction or hemorrhage. The cerebral infarction is characterized by the blockage of the artery either by… |
| Moxonidine | An imidazoline/α-2 receptor agonist used to treat hypertension, especially in cases where ACE inhibitors, β-blockers, calcium channel blockers, and thiazides are not appropriate or provide inadequate blood pressure control. |
| Muzolimine | Not Annotated |
| N-(6-Aminohexyl)-5-Chloro-1-Naphthalenesulfonamide | Not Available |
| Nadolol | A non-selective beta-adrenergic antagonist used for the management of arrhythmias, angina pectoris, and hypertension. |
| Nadroparin | A low molecular weight heparin used for the prophylaxis of thrombotic events and deep vein thrombosis, and prevent unstable angina and non-Q-wave myocardial infarction. |
| Naftidrofuryl | A peripheral vasodilator indicated in the treatment of chronic venous ulcers. |
| Naftopidil | Naftopidil has been investigated for the treatment of Disorder of Urinary Stent. |
| Naphazoline | A sympathomimetic vasoconstrictor used for the symptomatic relief of redness and itching of the eye, and nasal congestion. |
| Naproxcinod | Investigated for use/treatment in pain (acute or chronic), inflammatory disorders (unspecified), osteoarthritis, and arthritis and arthritic pain. |
| Naratriptan | A 5-HT1B/1D receptor agonist used to treat migraines. |
| Nebivolol | A beta blocking agent used to treat hypertension and aid in the management of heart failure. |
| Nesiritide | A recombinant natriuretic peptide used for the treatment of patients with acutely decompensated congestive heart failure who have dyspnea at rest or with minimal activity. |
| Niacin | A B vitamin used to treat hypertriglyceridemia and pellagra. |
| Nicardipine | A calcium channel blocker used for the short-term treatment of hypertension and chronic stable angina. |
| Nicergoline | An ergot derivative use for the treatment of symptoms associated with cerebrovascular abnormalities. |
| Nicofuranose | Not Annotated |
| Nicorandil | A vasodilatory drug that functions through potassium channels and intracellular cGMP concentrations commonly used to treat angina. |
| Nicotinyl alcohol | A direct-acting peripheral vasodilator that causes flushing and may decrease blood pressure. It is used in vasospasm and threatened gangrene. [PubChem] |
| Nifedipine | A dihydropyridine calcium channel blocker indicated for the management of several subtypes of angina pectoris, and hypertension. |
| Nifekalant | Nifekalant is under investigation in clinical trial NCT03855826 (Evaluation of the Efficacy and Safety of Nifekalant Hydrochloride (NIF) Injection). |
| Niguldipine | Niguldipine is a calcium channel blocker drug (CCB) with a1-adrenergic antagonist properties. |
| Niludipine | Niludipine is a calcium channel blocker. |
| Nilvadipine | A calcium channel blocker used to manage arterial hypertension. |
| Nimodipine | A calcium channel blocker used to improve neurological outcomes in patients with subarachnoid hemorrhage due to a ruptured intracranial aneurysm. |
| Nisoldipine | A calcium channel blocker used as monotherapy or combined with other drugs for the treatment of hypertension. |
| Nitrendipine | A dihydropyridine calcium channel blocker indicated in the treatment of arterial hypertension. |
| Nitric Oxide | A vasodilating agent used in the treatment of hypoxic respiratory failure in premature neonates. |
| Nitroaspirin | Nitroaspirin has been investigated for the treatment of Intermittent Claudication. |
| Nitroglycerin | A nitrate vasodilator used to treat or prevent angina, heart failure, hypertension, and anal fissures. |
| Nitroprusside | A direct acting vasodilator used to treat hypertension, to induce controlled hypotension to reduce postoperative bleeding, and to manage acute heart failure. |
| Nizofenone | Not Annotated |
| Norepinephrine | A sympathomimetic used in the control of blood pressure during various hypotensive states and as an adjunct treatment during cardiac arrest. |
| Nylidrin | A vasodilator used to treat patients with peripheral vascular disorders, and elderly patients with symptoms associated with organic mental disorders. |
| Octopamine | Octopamine is structurally similar to norepinephrine. It has been used as a nootropic, and therefore it and all of its enantiomer are prohibited by the World Anti-doping Agency (WADA) as… |
| Oglufanide | Investigated for use/treatment in hepatitis (viral, C). |
| Olmesartan | An angiotensin receptor blocker (ARB) used in the treatment of hypertension. |
| Olprinone | Not Annotated |
| Omapatrilat | For the treatment of hypertension. |
| Ornipressin | Not Annotated |
| Otilonium | A spasmolytic medication used to treat irritable bowel syndrome (IBS). |
| Ouabain | For the treatment of atrial fibrillation and flutter and heart failure |
| Oxprenolol | A non-selective beta-adrenergic antagonist used to treat hypertension, angina pectoris, arrhythmias, and anxiety. |
| Oxyfedrine | Not Annotated |
| Oxymatrine | Oxymatrine is under investigation in clinical trial NCT02202473 (Oxymatrine Plus Lamivudine Combination Therapy Versus Lamivudine Monotherapy for Chronic Hepatitis B Infected Subjects). |
| Oxymetazoline | An alpha-1A adrenoceptor agonist used to treat nasal congestion, allergic reactions of the eye, and facial erythema associated with rosacea. |
| Ozagrel | Ozagrel has been used in trials studying the treatment of Dry Eye Syndromes. |
| PACAP38 | Not Available |
| Papaverine | An alkaloid used to treat many types of smooth muscle spasms such as “vascular spasms” associated with acute myocardial infarction and angina pectoris, as well as “visceral spasms”. |
| Pargyline | For the treatment of moderate to severe hypertension. |
| Parnaparin | A low molecular weight heparin (LMWH) used to prevent blood clots, specifically deep vein thrombosis. |
| Penbutolol | A beta-adrenergic antagonist used for the management of mild to moderate arterial hypertension, alone or in combination with other antihypertensive agents. |
| Pentaerythritol tetranitrate | Used for the treatment of angina pectoris . |
| Pentolinium | Used to produce controlled hypotension during surgical procedures and in hypertensive crises. |
| Pentoxifylline | A methylxanthine derivative used to treat intermittent claudication caused by chronic occlusive arterial disease of the limbs. |
| Perhexiline | For the management of severe angina pectoris. |
| Perindopril | An ACE inhibitor prodrug used to treat hypertension, mild to moderate congestive heart failure, and to reduce cardiovascular risk in patients with hypertension or post-myocardial infarction. |
| Perindoprilat | The active metabolite of the prodrug Perindopril. |
| Peruvoside | Not Annotated |
| Phenol | An antiseptic and disinfectant used in a variety of settings. |
| Phenoxybenzamine | An alpha adrenergic antagonist used to treat pheochromocytoma and episodes of hypertension and sweating. |
| Phentolamine | An alpha-adrenergic blocker used to treat hypertensive episodes, diagnose pheochromocytoma, treat norepinephrine administration site reactions, and reverse soft tissue anesthesia and mydriasis. |
| Phenylephrine | An alpha-1 adrenergic agonist used in the management of hypotension, generally in the surgical setting associated with the use of anesthetics. |
| Phenylpropanolamine | A sympathomimetic that was previously used in nasal decongestants and weight loss products, but has been withdrawn by the FDA due to safety risks and lack of efficacy. |
| Phosphocreatine | A cardioprotective agent indicated for use in cardiac surgery. |
| Pilsicainide | Pilsicainide has been investigated for the treatment of Paroxysmal Atrial Fibrillation. |
| Pimobendan | Not Annotated |
| Pinacidil | Pinacidil is a cyanoguanidine drug that acts by opening ATP-sensitive potassium channels, leading to peripheral vasodilatation of arterioles and decreasing peripheral vascular resistance. The above processes result in reduced blood… |
| Pinaverium | A spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and functional disorders of the biliary tract. |
| Pindolol | A beta adrenoceptor antagonist used to treat hypertension, edema, ventricular tachycardias, and atrial fibrillation. |
| Pirbuterol | A beta-2 adrenergic agonist and bronchodilator used for the symptomatic treatment of asthma. |
| Piretanide | A loop diuretic used to manage essential arterial hypertension and edema cardiac, hepatic, and renal origin. |
| Plasminogen | Plasma-derived human plasminogen administered intravenously to treat type 1 plasminogen deficiency (hypoplasminogenemia). |
| Platelet Activating Factor | Not Available |
| Plumbagin | Plumbagin is a compound investigated for its anticancer activity. It has been found that it inactivates the Akt/NF-kB, MMP-9 and VEGF pathways. |
| Polidocanol | A sclerosing agent used for the treatment of uncomplicated spider veins and uncomplicated reticular veins, all less than 3 mm in diameter, in the lower extremity. |
| Polythiazide | A thiazide diuretic used in the management of hypertension and treatment of edema. |
| Practolol | Used in the emergency treatment of cardiac arrhythmias. |
| Prajmaline | Not Annotated |
| Prazosin | An alpha-blocker that causes a decrease in total peripheral resistance and is used to treat hypertension. |
| Prenalterol | Not Annotated |
| Prenylamine | Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias. |
| Procainamide | A medication used to treat life threatening ventricular arrhythmias. |
| Propafenone | A Class 1C antiarrhythmic agent used in the management of paroxysmal atrial fibrillation/flutter and ventricular arrhythmias. |
| Propranolol | A non-selective beta adrenergic antagonist used to treat hypertension, angina, atrial fibrillation, myocardial infarction, migraine, essential tremor, hypertrophic subaortic stenosis, and pheochromocytoma. |
| Proscillaridin | Proscillaridin is a cardiac glycoside that is derived from plants of the genus Scilla and in Drimia maritima (Scilla maritima). Studies suggest the potential cytotoxic and anticancer property of proscillaridin,… |
| Protein C | A medication used to treat protein C deficiency leading to purpura fulminans or coumarin-induced skin necrosis. |
| Pseudoephedrine | An alpha and beta adrenergic agonist used to treat nasal and sinus congestion, as well as allergic rhinitis. |
| Puerarin | Puerarin has been investigated for the treatment of Alcohol Abuse. |
| QGC-001 | QGC001 has been used in trials studying the treatment of Essential Hypertension. |
| Quinapril | An ACE inhibitor prodrug used to treat hypertension, congestive heart failure, and slow rate of progression of renal disease. |
| Quinaprilat | The active metabolite of the prodrug quinapril. |
| Quinethazone | Used to treat hypertension. |
| Quinidine | A medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias. |
| Racepinephrine | A bronchodilator used to treat intermittent asthma. |
| Ramipril | An ACE inhibitor used for the management of hypertension and the reduction of cardiovascular mortality following myocardial infarction in hemodynamically stable patients with clinical signs of congestive heart failure. |
| Ramiprilat | The active metabolite of the prodrug Ramipril. |
| Ranolazine | An anti-anginal drug used for the treatment of chronic angina. |
| Raubasine | Not Annotated |
| Remikiren | For the treatment of hypertension and heart failure |
| Reserpine | For the treatment of hypertension |
| Reteplase | A purified form of human tissue plasminogen activator used in the emergency treatment of myocardial infarction, ischemic stroke, and pulmonary emboli. |
| Reviparin | By the FDA, reviparin is indicated for the treatment of deep vein which may lead to pulmonary embolism in pediatric patients. It is also indicated for the long-term treatment of… |
| Rilmenidine | An I1-imidazoline receptor agonist used to treat hypertension. |
| Risedronic acid | A bisphosphonate used to treat osteoporosis and Paget’s disease. |
| Rufinamide | An antiepileptic drug used as adjunctive therapy to treat seizures associated with Lennox-Gastaut Syndrome (LGS). |
| S-Ethylisothiourea | S-Ethylisothiourea is a nitric oxide synthase inhibitor. |
| S-Nitrosoglutathione | Not Annotated |
| Saprisartan | Saprisartan is used in the treatment of hypertension and heart failure. |
| Sarpogrelate | Sarpogrelate has been investigated for the treatment of Diabetes Mellitus, Diabetic Nephropathy, Coronary Artery Disease, and Renal Insufficiency, Chronic. |
| Saruplase | Not Annotated |
| Selexipag | A non prostanoid IP prostacyclin receptor agonist used to treat pulmonary arterial hypertension. |
| Semuloparin | Investigated for use/treatment in thrombosis. |
| Sildenafil | A phosphodiesterase inhibitor used for the treatment of erectile dysfunction. |
| Simendan | Simendan is under investigation in clinical trial NCT00527059 (Renal Effects of Levosimendan in Patients Admitted With Acute Decompensated Heart Failure). |
| SKF-96365 free base | SKF-96365 is a receptor-mediated calcium entry (RMCE) inhibitor structurally different from other calcium antagonists. |
| Sodium tetradecyl sulfate | An anionic surfactant used to treat varicose veins of the lower extremities. |
| SOR-C13 | SOR-C13 is under investigation in clinical trial NCT01578564 (Safety and Tolerability Study of SOR-C13 in Subjects With Advanced Cancers Commonly Known to Express the TRPV6 Channel). |
| Sotalol | A methane sulfonanilide beta adrenergic antagonist used to treat life-threatening ventricular arrhythmias and to maintain sinus rhythm in atrial fibrillation or flutter. |
| Sparteine | Sparteine is a plant alkaloid derived from Cytisus scoparius and Lupinus mutabilis which may chelate calcium and magnesium. It is a sodium channel blocker, so it falls in the category… |
| Spiradoline | Spiradoline has been investigated for the basic science of Bipolar Depression. |
| Spirapril | Spirapril is an ACE inhibitor class drug used to treat hypertension. |
| Spironolactone | An aldosterone receptor antagonist used to treat edema, hypertension, heart failure, and aldosteronism. |
| Streptokinase | A purified fibrinolytic bacterial protein used to breakdown thrombosis in myocardial infarction, pulmonary embolism, and venous thromboembolism. |
| Suloctidil | Not Annotated |
| Sulodexide | A drug used to treat chronic venous ulcers in the legs. |
| Sumatriptan | A serotonin receptor agonist used to treat migraines and cluster headaches. |
| Synephrine | Synephrine, also referred to as, p-synephrine, is naturally occurring alkaloid. It is present in approved drug products as neo-synephrine, its m-substituted analog. p-synephrine and m-synephrine are known for their longer… |
| Tadalafil | A phosphodiesterase 5 inhibitor used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension. |
| Talinolol | Talinolol has been investigated for the basic science of Gastrointestinal Motility Disorder. |
| Tedisamil | Investigated for use/treatment in arrhythmia, atrial fibrillation, and angina. |
| Telmisartan | An ARB used to treat hypertension, diabetic nephropathy, and congestive heart failure. |
| Temocapril | Temocapril is an ACE inhibitor primarily indicated in the treatment of hypertension and congestive heart failure, diabetic nephropathy, and improvement of prognosis for coronary artery diseases (including acute myocardial infarction). |
| Tenecteplase | A modified form of recombinant human tissue plasminogen activator used in the emergency treatment of myocardial infarction and pulmonary emboli. |
| Terlipressin | A drug used to treat bleeding caused by esophageal varices. |
| Terodiline | Not Annotated |
| Tertatolol | Tertatolol is a beta blocker. |
| Tetraethylammonium | Tetraethylammonium is an experimental drug with no approved indication. |
| Tetrahydropalmatine | Tetrahydropalmatine is under investigation in clinical trial NCT02118610 (Treatment of Schizophrenia With L-tetrahydropalmatine (l-THP): a Novel Dopamine Antagonist With Anti-inflammatory and Antiprotozoal Activity). |
| Tetrandrine | Not Annotated |
| Tetrodotoxin | For the treatment of chronic and breakthrough pain in advanced cancer patients as well as for the treatment of opioid dependence. |
| Tetryzoline | An alpha-adrenergic agonist used in the temporary symptomatic relief of discomfort and redness of the eyes due to minor irritations, as well as alleviate nasal congestion. |
| Tezosentan | Investigated for use/treatment in congestive heart failure, liver disease, and heart disease. |
| Theobromine | theobromine is used as a vasodilator, a diuretic, and heart stimulant. And similar to caffeine, it may be useful in management of fatigue and orthostatic hypotension. |
| Theodrenaline | Theodrenaline is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation). |
| Theophylline | A xanthine used to manage the symptoms of asthma, COPD, and other lung conditions caused by reversible airflow obstruction. |
| Tibolone | For the relief of post-menopausal symptoms and for the prevention of osteoporosis . |
| Ticlopidine | A platelet aggregation inhibitor used in the prevention of conditions associated with thrombi, such as stroke and transient ischemic attacks (TIA). |
| Tienilic acid | For the treatment of hypertension. |
| Timolol | A non-selective beta adrenergic blocker used in the treatment of elevated intraocular pressure in ocular hypertension or open angle glaucoma. |
| Tinzaparin | A low molecular weight heparin used for the treatment of acute symptomatic deep vein thrombosis with or without pulmonary embolism when administered in conjunction with warfarin. |
| Tiracizine | Not Annotated |
| Tirofiban | A platelet aggregation inhibitor used to prevent thrombotic events in non-ST elevated acute coronary syndrome. |
| Tocainide | An orally active class 1b antiarrhythmic agent that interferes with cardiac sodium channels and typically used to treat ventricular arrhythmias. |
| Tocopherylquinone | Not Annotated |
| Tolazoline | A vasodilator used to treat pulmonary artery anomalies. |
| Tolfenamic acid | In the information for tolfenamic acid, it is stated that this drug, being an NSAID, is effective in treating the pain associated with the acute attack of migraines in adults. |
| Tolvaptan | A selective vasopressin V2-receptor antagonist to slow kidney function decline in patients at risk for rapidly progressing autosomal dominant polycystic kidney disease (ADPKD). Also used to treat hypervolemic and euvolemic hyponatremia. |
| Torasemide | A diuretic used to treat hypertension and edema associated with heart failure, renal failure, or liver disease. |
| Trafermin | Investigated for use/treatment in coronary artery disease, peripheral vascular disease, periodontal disease, bone fractures, entero-related fistulae, and diabetic foot ulcers. |
| Trandolapril | A prodrug of an ACE inhibitor used to treat hypertension, congestive heart failure, and to improve survival following a myocardial infarction. |
| Tranilast | For the treatment of bronchial asthma, keloid and hypertrophic scar, and allergic disorders such as asthma, allergic rhinitis and atopic dermatitis. |
| Trapidil | Used in the treatment of chronic stable angina . |
| Treprostinil | A prostacyclin vasodilator for the treatment of pulmonary arterial hypertension to relieve exercise associated symptoms and to prevent clinical deterioration after stopping epoprostenol. |
| Triamterene | A potassium-sparing diuretic used in the treatment of edema and in the management of hypertension. |
| Trichlormethiazide | Used in the treatment of oedema (including that associated with heart failure) and hypertension. |
| Trimazosin | Trimazosin is a sympatholytic alpha blocker. |
| Trimetazidine | A piperazine derivative indicated as an adjunct therapy in symptomatic treatment of stable angina pectoris. |
| Trimethaphan | For the controlled reduction of blood pressure during surgery and in the treatment of hypertensive emergencies. |
| Tyrosol | Not Annotated |
| Ulobetasol | A lipocortin corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses. |
| Unoprostone | A prostaglandin analogue used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are clinically unresponsive to other ocular antihypertensive agents. |
| Urapidil | A combination adrenergic antagonist and serotonin agonist given orally for the treatment of essential hypertension and intravenously in hypertensive emergencies. |
| Valsartan | An angiotensin-receptor blocker used to manage hypertension alone or in combination with other antihypertensive agents and to manage heart failure in patients who are intolerant to ACE inhibitors. |
| Vardenafil | A phosphodiesterase 5 inhibitor used to treat erectile dysfunction. |
| Vasoactive intestinal peptide | Not Annotated |
| Vasomera | Not Available |
| Vasopressin | A peptide hormone used to increase blood pressure in patients with vasodilatory shock who are resistant to fluid and catecholamine therapy. |
| Verapamil | A non-dihydropyridine calcium channel blocker used in the treatment of angina, arrhythmia, and hypertension. |
| Vesnarinone | Vesnarinone has been used in trials studying the treatment of HIV Infections and Sarcoma, Kaposi. |
| Vinburnine | Not Annotated |
| Vincamine | Vincamine is a monoterpenoid indole alkaloid obtained from the leaves of Vinca minor with a vasodilatory property. Studies indicate that vincamine increases the regional cerebral blood flow. |
| Vinpocetine | A synthetic derivative of a vinca alkaloid used to treat neurological symptoms of cerebrovascular disease. |
| WIN 55212-2 | WIN 55,212-2 is a chemical described as an aminoalkylindole derivative, which produces effects similar to those of cannabinoids such as tetrahydrocannabinol (THC) but has an entirely different chemical structure. It… |
| Xanthinol | A vasodilatory niacin found in diet supplements. |
| Xipamide | A diuretic indicated in the treatment of edema. |
| Xylometazoline | A direct-acting alpha-adrenergic agonist used for the symptomatic treatment of nasal congestion and minor inflammation due to allergies or colds. |
| Y-27632 | Y-27632 is an inhibitor of Rho-associated protein kinase. It inhibits calcium sensitization to affect smooth muscle relaxation. |
| Z-160 | Z160 has been used in trials studying the treatment of Postherpetic Neuralgia and Lumbosacral Radiculopathy. |
| Zofenopril | An ACE inhibitor indicated in the treatment of hypertension. |
| Zonisamide | A sulfonamide anticonvulsant used to treat partial seizures. |