An endogenous purine nucleoside used clinically as a rapid-acting antiarrhythmic and coronary vasodilator. It transiently slows or blocks AV nodal conduction via A₁ receptor activation, making it first-line for acute termination of paroxysmal supraventricular tachycardia (PSVT). It has an ultrashort half-life (<10 seconds) and is also used in pharmacologic cardiac stress testing due to A₂A-mediated coronary vasodilation.

Links