Description: Drugs for Constipation
DRUG | DRUG DESCRIPTION |
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Alvimopan | An opioid antagonist used to reduce healing time of the upper and lower gastrointestinal tract following surgical procedures that involve bowel resection with primary anastomosis. |
Bisacodyl | A stimulant laxative used for the temporary relief of occasional constipation and cleansing of the colon as a preparation for colonoscopy in adults. |
Bisoxatin | For use in the treatment of constipation in the absence of bowel obstruction and for surgical preparation of the colon . |
Calcium polycarbophil | A bulk forming laxative used to treat constipation. |
Castor oil | An ingredient used in a variety of natural health products. |
Dantron | A drug used to relieve acute and chronic inflammation of the oral cavity and oropharynx. |
Docusate | A medication used to treat constipation associated with dry, hard stools, or opioid induced constipation. |
Elobixibat | Elobixibat has been used in trials studying the treatment and basic science of Dyslipidemia, Constipation, Chronic Constipation, Functional Constipation, and Chronic Idiopathic Constipation. |
Glycerin | It is used as a solvent, emollient, pharmaceutical agent, and sweetening agent. |
Karaya gum | An extract from Karaya gum used in allergy testing. |
Lactitol | An orally administered osmotic laxative used to treat chronic idiopathic constipation. |
Lactulose | A disaccharide derivative of lactose used to treat constipation and portal systemic encephalopathy. |
Linaclotide | A guanylate cyclase-C agonist used to treat different types of constipation, such as irritable bowel syndrome-related constipation, idiopathic constipation, and functional constipation. |
Lubiprostone | A prostaglandin derivative used to treat constipation caused by irritable bowel syndrome and opioid-use. |
Magnesium carbonate | An antacid used for symptomatic relief of heartburn, indigestion, and upset stomach. |
Magnesium citrate | A laxative used in bowel preparation for colonoscopy or as a magnesium supplement. |
Magnesium oxide | A compound commonly used as a laxative for the symptomatic relief of acid indigestion and upset stomach, and in health supplements for cardiovascular and neuromuscular health. |
Magnesium peroxide | Not Annotated |
Magnesium sulfate | A drug used to treat convulsions during pregnancy, nephritis in children, magnesium deficiency, and tetany. |
Mannitol | A sugar alcohol used to test for asthma, to reduce intracranial and intraocular pressure, to measure glomerular filtration rate, and to manage pulmonary symptoms associated with cystic fibrosis. |
Methylcellulose | A compound used as a bulk forming laxative and is not an approved medication. |
Methylnaltrexone | A μ-opioid antagonist used for the treatment of opioid-induced constipation in palliative patients that are inadequately responding to laxative therapy. |
Mineral oil | Mineral oil is not considered an active pharmacological ingredient in pharmaceutical preparations and so has no official indication. It is typically present in topical formulations as an emollient and occlusive… |
Naldemedine | An opioid antagonist used to to treat opioid-induced constipation. |
Naloxegol | A peripherally-selective opioid antagonist used to treat opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain. |
Naloxone | An opioid receptor antagonist used to rapidly reverse an opioid overdose. Also included in some drug formulations as an abuse deterrent to prevent injection. |
Oxyphenisatin | A laxative that undergoes enterohepatic circulation. It may cause jaundice. |
Pentaerithrityl | Not Annotated |
Phenolphthalein | A drug used for symptomatic relief of constipation and bowel cleansing prior to medical procedures. |
Picosulfuric acid | A stimulant laxative used for cleansing of the colon as a preparation for colonoscopy in adults. |
Plantago ovata seed | A plant extract indicated in the treatment of occasional constipation. |
Plecanatide | A laxative used to treat chronic idiopathic constipation and IBS with constipation. |
Polyethylene glycol | A laxative used to treat constipation and used for bowel preparation before colonoscopies and other procedures. |
Prucalopride | A 5-HT4 receptor agonist indicated to treat adults with chronic idiopathic constipation. |
Sennosides | A laxative used to treat constipation. |
Sodium lauryl sulfoacetate | A laxative indicated in the treatment of constipation and bowel preparation for rectal endoscopy. |
Sodium phosphate, monobasic | A source of phosphorus used prevent or correct hypophosphatemia in patients with restricted or no oral intake. |
Sodium sulfate | An agent used for bowel cleansing prior to colonoscopy or barium enema X-ray examination. |
Sodium tartrate | It acts as an emulsifier and pH control agent in food products , . In the laboratory, it is used while performing the Karl Fischer equation, which is used to… |
Sorbitol | A product that can be used as a laxative to relieve constipation, and also as a urologic irrigating fluid. May also be used as a pharmaceutical sweetener. |
Tegaserod | A serotonin-4 (5-HT4) receptor agonist indicated for the treatment of constipation predominant irritable bowel syndrome (IBS-C) specifically in women under the age of 65. There is currently no safety or efficacy data for use of tegaserol in men. |
Tenapanor | An NHE3 inhibitor indicated for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic kidney disease, |
Description: Drugs used to prevent nausea and vomiting
DRUG | DRUG DESCRIPTION |
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Alizapride | A dopamine antagonist used to prevent nausea and vomiting associated with medical procedures, surgeries, and cancer therapies. |
Alosetron | A 5-HT3 antagonist used to treat diarrhea-predominant IBS. |
Amisulpride | A dopamine D2 receptor antagonist used in the treatment of acute and chronic schizophrenia, and in the prevention and treatment of postoperative nausea and vomiting in adults. |
Aprepitant | A substance P/neurokinin 1 receptor antagonist used to treat nausea and vomiting caused by chemotherapy and surgery. |
Azasetron | Not Annotated |
Bromopride | A substituted benzamide, closely related to metoclopramide, used as an antiemetic. |
Casopitant | Investigated for use/treatment in urinary incontinence and adverse effects (chemotherapy). |
Chlorpromazine | A phenothiazine antipsychotic used to treat nausea, vomiting, preoperative anxiety, schizophrenia, bipolar disorder, and severe behavioral problems in children. |
Clebopride | A dopamine antagonist used to treat symptoms associated with functional gastrointestinal disorders. Clebopride may also be used to treat nausea and vomiting associated with chemotherapy. |
Cyclizine | An antihistamine and antiemetic drug used for the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness, and vertigo. |
Dexamethasone | A glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders. |
Dexanabinol | Investigated for use/treatment in traumatic brain injuries and neurologic disorders. |
Dimenhydrinate | A medication used to prevent and treat nausea, vomiting, vertigo, and motion sickness. |
Diphenhydramine | A H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria, insect bites/stings, and allergic rashes. |
Diphenidol | An antiemetic agent used for the prevention and symptomatic treatment of nausea and vomiting associated with various conditions as Meniere’s disease and surgery of the middle and inner ear. |
Dixyrazine | Not Annotated |
Dolasetron | An antinauseant and antiemetic used in chemotherapy and postoperatively. |
Domperidone | A dopamine receptor antagonist used as a peristaltic stimulant and anti-emetic agent for dyspepsia, indigestion, epigastric pain, nausea, and vomiting. |
Doxylamine | An antihistamine used to treat insomnia and allergy symptoms and is used with pyridoxine in the treatment of nausea and vomiting in pregnancy. |
Droperidol | A butyrophenone derivative and dopamine antagonist used to prevent and treat postoperative nausea and vomiting. |
Fosaprepitant | An antiemetic drug used in combination with other antiemetic agents for the prevention of acute and delayed nausea and vomiting caused by chemotherapy. |
Granisetron | A 5HT3 antagonist used to treat nausea and vomiting in cancer therapy and postoperatively. |
Haloperidol | An antipsychotic agent used to treat schizophrenia and other psychoses, as well as symptoms of agitation, irritability, and delirium. |
Lorazepam | A short-acting benzodiazepine commonly used to treat panic disorders, severe anxiety, and seizures. |
Maropitant | Maropitant, used as maropitant citrate, is a neurokinin receptor antagonist, which was developed by Zoetis specifically for the treatment of motion sickness and vomiting in dogs. It was approved by… |
Meclizine | A histamine H1 antagonist used to treat nausea, vomiting, and dizziness associated with motion sickness. |
Methylprednisolone | A corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases. |
Metoclopramide | An antiemetic agent and dopamine D2 antagonist used in the treatment of gastroesophageal reflux disease, prevention of nausea and vomiting, and to stimulate gastric emptying. |
Metopimazine | Not Annotated |
Nabilone | A synthetic delta-9-THC used in the treatment of anorexia and weight loss in HIV patients as well as nausea and vomiting in cancer chemotherapy. |
Olanzapine | An antipsychotic drug used in the management of schizophrenia, bipolar 1 disorder, and agitation associated with these disorders. |
Ondansetron | A serotonin 5-HT3 receptor antagonist used to prevent nausea and vomiting in cancer chemotherapy and postoperatively. |
Palonosetron | A serotonin antagonist used in the prophylaxis or management of vomiting that results from emetogenic chemotherapy, and for the management of postoperative nausea and vomiting. |
Peppermint oil | An ingredient used in a variety of natural health products and is not an approved medication. |
Prochlorperazine | A phenothiazine derivative used in the treatment of schizophrenia and anxiety and to relieve severe nausea and vomiting. |
Promazine | A phenothiazine used to manage schizophrenia. |
Ramosetron | A selective 5-HT3 antagonist used as an antiemetic for chemotherapy- and postoperative-associated nausea and vomiting. It may also possess efficacy in irritable bowel syndrome. |
Scopolamine | A belladonna alkaloid with anticholinergic effects indicated for the treatment of nausea and vomiting associated with motion sickness and postoperative nausea and vomiting (PONV). |
Thiethylperazine | A drug used for the treatment of nausea and vomiting. |
Trifluoperazine | A phenothiazine used to treat depression, anxiety, and agitation. |
Triflupromazine | Used mainly in the management of psychoses. Also used to control nausea and vomiting. |
Trimethobenzamide | An antiemetic used to treat postoperative nausea and vomiting and nausea associated with gastroenteritis. |
Tropisetron | A 5HT-3 receptor antagonist used as an antiemetic in the treatment of chemotherapy-induced nausea and vomiting. |
Vofopitant | Vofopitant has been used in trials studying the treatment of PTSD, Primary Insomnia, and Sleep Initiation and Maintenance Disorders. |