Comparison of different types of insulin, including examples:

Type of InsulinOnsetPeakDurationExamples
Rapid-Acting15 minutes1-2 hours2-4 hoursInsulin aspart (NovoLog), Insulin lispro (Humalog), Insulin glulisine (Apidra)
Short-Acting30 minutes2-3 hours3-6 hoursRegular insulin (Humulin R, Novolin R)
Intermediate-Acting1-2 hours4-12 hours12-18 hoursInsulin NPH (Humulin N, Novolin N)
Long-Acting1-2 hoursMinimal peakUp to 24 hoursInsulin glargine (Lantus, Basaglar), Insulin detemir (Levemir)
Ultra-Long-Acting6 hoursNo peakOver 24 hoursInsulin degludec (Tresiba)
PremixedVariesVariesVariesHumulin 70/30, Novolog Mix 70/30

Key Points

  • Rapid-Acting Insulin: Ideal for mealtime blood sugar control
  • Short-Acting Insulin: Used for mealtime control but takes longer to start working
  • Intermediate-Acting Insulin: Provides basal insulin coverage, often used in combination with rapid- or short-acting insulin
  • Long-Acting Insulin: Provides consistent basal insulin coverage throughout the day
  • Ultra-Long-Acting Insulin: Offers extended basal coverage with minimal peaks
  • Premixed Insulin: Combines rapid- or short-acting and intermediate-acting insulin for convenience