A class III agent that prolongs the duration of the action potential; amiodarone is used to treat refractory ventricular and supraventricular tachycardia, A-Fib, conduction block.
Adverse effects: Pulmonary fibrosis, which occurs in ±6% of Pts taking the drug, hypothyroidism, hyperthyroidism, deposits in the cornea—causing photosensitivity and/or skin-blue/gray skin pigmentation, leukocytoclastic vasculitis, hepatitis, ↑ digitoxin levels, neurotoxicity, GI toxicity
Synonyms
Cordarone