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Drug
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Description
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2-deoxyglucose
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As of July 2013, there is no approved therapeutic indication for 2-deoxyglucose. 2-deoxyglucose may have several potential indications as an adjunct to chemotherapy and radiotherapy in the treatment of solid…
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2-mercaptobenzothiazole
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Not Annotated
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5′-Guanylylmethylenebisphosphonate
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Not Available
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5′-S-methyl-5′-thioadenosine
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Not Available
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Acemannan
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Acemannan is under investigation in clinical trial NCT03250923 (Celagace™ Orarinse Solution for Treatment of Candidiasis).
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Acetarsol
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An anti infective used to treat a wide variety of infections in the body.
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Acetic acid
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An antimicrobial agent used to treat susceptible infections of the external auditory canal.
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Acetylcysteine zinc
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Not Available
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Aconiazide
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Not Annotated
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Acriflavine
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A topical antiseptic indicated in the treatment of infected wounds and for skin disinfection.
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Acteoside
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Acteoside is under investigation in clinical trial NCT02662283 (Validity and Security of Reh-acteoside Therapy for Patients of IgA Nephropathy).
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Adafosbuvir
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Adafosbuvir is under investigation in clinical trial NCT02894905 (A Study to Evaluate the Effect of Renal Impairment on the Pharmacokinetics of AL-335).
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Adefovir
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Not Annotated
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Adefovir dipivoxil
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A nucleotide analog used to treat chronic hepatitis B.
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Afabicin
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Afabicin is under investigation in clinical trial NCT03723551 (Study to Assess Safety, Tolerability and Efficacy of Afabicin in The Treatment of Participants With Bone or Joint Infection Due to Staphylococcus).
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Ajoene
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Not Annotated
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Alatrofloxacin
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A fluoroquinolone antibiotic used to treat a variety of bacterial infections.
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Albaconazole
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Albaconazole has been used in trials studying the basic science of Onychomycosis.
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Albendazole oxide
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Not Annotated
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Aldesleukin
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A recombinant analog of interleukin-2 used to induce an adaptive immune response in the treatment of renal cell carcinoma.
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Allicin
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Allicin has been used in trials studying the treatment of Follicular Lymphoma.
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Allopurinol riboside
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Allopurinol riboside is a nucleoside analogue of allopurinol with a beta-D-ribofuranosyl moiety at the 1-position.
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Alovudine
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Investigated for use/treatment in HIV infection.
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Alovudine F-18
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Alovudine F-18 is under investigation in clinical trial NCT02819024 (Dexamethasone Effects in Patients With Refractory Non-Small Cell Lung Cancer Using FLT Positron Emission Tomography).
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Aluminium acetotartrate
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Not Annotated
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Amantadine
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A medication used to treat dyskinesia in Parkinson’s patients receiving levodopa, as well as extrapyramidal side effects of medications.
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Amdinocillin
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Used in the treatment of urinary tract infections caused by some strains of E. coli and klebsiella and enterobacter species. Used mainly against Gram negative organisms.
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Aminacrine
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A slow-acting germicide effective against bacteria and fungi which is included in drug formulations for its anti-septic properties.
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Aminosalicylic acid
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An aminosalicylate drug used to induce remission in ulcerative colitis.
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Amithiozone
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Amithiozone has been used in trials studying the treatment of Mycobacterium Avium-intracellulare Infection.
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Ammonium trichlorotellurate
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Ammonium trichlorotellurate is an investigational compound with anti-tumour and anti-inflammatory properties.
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Amodiaquine
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An antimalarial drug.
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Amonafide
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Investigated for use/treatment in breast cancer, ovarian cancer, and prostate cancer.
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Amorolfine
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A morpholine derivative commonly applied as a lacquer for onychomycosis but is also used for superficial dermatomycosis.
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Amphomycin
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Not Annotated
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Amprenavir
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A protease inhibitor used to treat HIV infection.
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Amprolium
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Amprolium is a coccidiostat used in poultry.
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Andrographolide
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Investigated for use/treatment in ulcerative colitis.
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Anidulafungin
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An antifungal used in the treatment of several types of candida infections.
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Anisomycin
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Anisomycin (sometimes known as flagecidin), is an antibiotic retrieved from the bacteria Streptomyces griseolus. This drug acts to inhibit bacterial protein and DNA synthesis.
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Ansuvimab
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A fully human monoclonal IgG1 antibody directed against the GP1,2 surface protein of Zaire ebolavirus that is an effective treatment for Ebola virus disease.
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Anti-SARS-CoV-2 REGN-COV2
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Anti-SARS-COV-2 REGN-COV2 is a combination of novel antibodies designed by Regeneron for both the prevention and treatment of SARS-COV-2, the virus that causes COVID-19. This drug is a combination of…
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Antimony potassium tartrate
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Antimony potassium tartrate is a schistosomicide possibly useful against other parasites. It has irritant emetic properties and may cause lethal cardiac toxicity among other adverse effects.
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Aphidicolin
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Aphidicolin is an antimitotic and antiviral metabolite of the mould Cephalosporium aphidicola. It inhibits DNA polymerase alpha and blocks DNA replication.[A259157, A259162]
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Aplaviroc
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Investigated for use/treatment in HIV infection.
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Arbekacin
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Arbekacin is used for the short term treatment of multi-resistant bacterial infections, such as methicillin-resistant Staphylococcus aureus (MRSA).
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Arsanilic acid
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An arsenical which has been used as a feed additive for enteric conditions in pigs and poultry. It causes blindness and is ototoxic and nephrotoxic in animals. [PubChem]
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Artefenomel
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Artefenomel has been investigated for the treatment of Malaria.
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Artemisinin
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A medication indicated in the treatment of malaria.
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Artemotil
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Artemotil, also known as β-arteether, is a semi-synthetic derivative of artemisinin and a fast acting blood schizonticide specifically indicated for the treatment of chloroquine-resistant Plasmodium falciparum malaria and cerebral malaria…
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Artenimol
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For the treatment of uncomplicated Plasmodium falciparum infection in adults, children, and infants aged 6 months and up weighing over 5 kg [FDA Label]. Used in combination with DB13941.
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Artesunate
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Artesunate is an artemesinin derivative indicated for the initial treatment of severe malaria.
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Asiaticoside
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Not Annotated
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Astegolimab
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Astegolimab is under investigation in clinical trial NCT04386616 (A Study to Evaluate the Safety and Efficacy of MSTT1041A (Astegolimab) or UTTR1147A in Patients With Severe COVID-19 Pneumonia).
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Atevirdine
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Atevirdine has been used in trials studying the treatment of HIV Infections.
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Atoltivimab
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Part of a product containing three monoclonal IgG1κ antibodies directed against the GP1,2 glycoprotein of Zaire ebolavirus. Together, these three antibodies act to neutralize viral particles and to recruit immune effectors for the destruction of both viral particles and infected cells.
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Atovaquone
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An antimicrobial indicated for the prevention and treatment of Pneumocystis jirovecii pneumonia (PCP) and for the prevention and treatment of Plasmodium falciparum malaria.
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Aurodox
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Aurodox is an antibiotic obtained from a streptomyces variant considered as possibly effective against streptococcus pyogenes infections. It may promote growth in poultry.
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Avdoralimab
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Avdoralimab is under investigation in clinical trial NCT04333914 (Prospective Study in Patients With Advanced or Metastatic Cancer and Sars-cov-2 Infection).
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Avilamycin
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Not Annotated
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AZD-5672
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Azd5672 has been used in trials studying the basic science and treatment of Pharmacokinetics, Renal Impairment, and Rheumatoid Arthritis.
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AZD7442
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AZD7442 is a combination of SARS-CoV-2 antibodies (AZD8895 + AZD1061) currently undergoing phase I clinical trials for the prevention and treatment of COVID-19. It was developed by AstraZeneca with the…
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Azidamfenicol
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Not Annotated
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Azlocillin
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For the treatment of infections caused by Pseudomonas aeruginosa, Escherichia coli, and Haemophilus influenzae.
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Azodicarbonamide
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Not Annotated
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Bacampicillin
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An ampicillin prodrug used to treat various susceptible bacterial infections in the body, such as respiratory infections and skin and subcutaneous tissue infections.
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Bafilomycin A1
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The bafilomycins refer to a category of toxic macrolide antibiotics that are derivatives of Streptomyces griseus. These compounds all appear in the same fermentation and have similar biological activity. Bafilomycins…
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Baloxavir
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Baloxavir is under investigation in clinical trial NCT04327791 (Combination Therapy With Baloxavir and Oseltamavir 1 for Hospitalized Patients With Influenza (The COMBO Trial 1)).
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Baloxavir marboxil
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A polymerase acidic endonuclease inhibitor used to treat uncomplicated influenza.
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Bambermycins
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Bambermycins are antibiotic complexes which are retrieved from the organism, Streptomyces bambergiensis. They are used as an additive in food ingested by chickens and swine. The bambermycin complex of antibiotics…
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Bamlanivimab
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A neutralizing human IgG1κ monoclonal antibody against the SARS-CoV-2 spike (S) protein for use in patients aged 12 and over at high risk of developing severe COVID-19.
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Basifungin
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Basifungin, also known as aureuobacidin A, is a phosphorylceramide synthase inhibitor , .
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Bedaquiline
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A diarylquinoline antimycobacterial used in combination with other antibacterials to treat pulmonary multidrug resistant tuberculosis (MDR-TB).
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Bekanamycin
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An aminoglycoside antibiotic indicated in the treatment of eye infections.
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Benzalkonium
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An antiseptic agent used as a preservative in medications or as a disinfectant in cleaning products.
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Benzethonium
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A medication used as to clean hands and clean minor cuts and scrapes.
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Benzimidazole
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Not Available
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Benznidazole
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A trypanocidal agent used to treat Chagas disease.
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Benzododecinium
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Benzododecinium is used as an antiseptic/disinfectant compound. It has been marketed as a tincture for antiseptic product for wounds in the Czech Republic.
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Benzoic acid
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An antimicrobial food additive.
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Bersacapavir
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Bersacapavir is under investigation in clinical trial NCT03365947 (Study of ARO-HBV in Normal Adult Volunteers and Patients With Hepatitis B Virus (HBV)).
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Besifloxacin
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A fluoroquinolone antibiotic agent used for the treatment of bacterial conjunctivitis.
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Betulinic Acid
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Betulinic Acid has been used in trials studying the treatment of Dysplastic Nevus Syndrome.
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Bibrocathol
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Not Annotated
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Bifonazole
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An azole antifungal drug used to treat fungal skin infections, such as dermatomycosis.
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Bismuth cation
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Not Annotated
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Bismuth subcitrate potassium
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A colloid used for the treatment of peptic ulcer and gastro-esophageal reflux disease (GERD).
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Bismuth subgallate
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A medication used to deodorize flatulence and stools as well as hemostasis in soft tissue surgery.
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Bithionol
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Bithionol, formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause serious skin disorders. Approvals of the…
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BMS-488043
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Investigated for use/treatment in HIV infection.
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BMS-955176
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BMS-955176 is under investigation in clinical trial NCT02415595 (Dose-finding Study of BMS-955176 to Treat HIV-1 Infected Treatment-naive Adults).
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Boric acid
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No FDA- or EMA-approved therapeutic indications on its own.
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Brefeldin A
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A metabolite from Penicillium brefeldianum that exhibits a wide range of antibiotic activity.
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Brilacidin
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Brilacidin is under investigation for the supportive care of Mucositis, Stomatitis, Mouth Diseases, and Head and Neck Neoplasms.
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Brilliant green cation
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An ingredient used in topical medications to prevent infections of the umbilical cord.
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Brincidofovir
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An oral lipid prodrug of cidofovir used in the treatment of human smallpox disease.
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Brivudine
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A drug used to treat herpes zoster.
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Brodimoprim
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Not Annotated
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Bronopol
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An antimicrobial compound used as a biocide and preservative.
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Broxuridine
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Broxuridine has been used in trials studying the treatment of Leukemia, Stage I Prostate Cancer, Stage IIB Prostate Cancer, and Stage IIA Prostate Cancer.
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Bunamidine
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Bunamidine is a veterinary anti-platyhelmintic agent used for taenia infestations.
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Butenafine
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A topical antifungal used to treat tinea versicolor, tinea pedis, tinea cruris, and tinea corporis.
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Butoconazole
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An imidazole antifungal used to treat vulvovaginal candidiasis.
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Cabotegravir
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An HIV-1 integrase inhibitor used for treatment and pre-exposure prophylaxis of HIV-1 infection.
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Cadexomer iodine
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Not Annotated
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Calanolide A
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For use in combination treatment of HIV infection (AIDS).
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Calcium sulfide
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Not Annotated
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Cambendazole
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Not Annotated
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Camphor
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A compound used topically to help relieve pain and also as a topical antiseptic. May also be used in vaporizers to help suppress coughing. This medication should not be swallowed.
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Candicidin
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Used in the topical treatment of vulvovaginal candidiasis.
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Capravirine
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Investigated for use/treatment in acquired immune deficiency syndrome (AIDS) and aids-related infections and HIV infection.
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Capric acid
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Decanoic acid is a solid. This compound belongs to the straight chain fatty acids. These are fatty acids with a straight aliphatic chain. The proteins that decanoic acid targets include…
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Carbamide peroxide
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A medication used to loosen ear wax, whiten teeth, and clean oral wounds.
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Carbendazim
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Carbendazim has been used in trials studying the treatment of Lymphoma and Unspecified Adult Solid Tumor, Protocol Specific.
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Carbocisteine
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A expectorant mucolytic used in the relief of respiratory of COPD and other conditions associated with increased mucus viscosity.
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Carbovir
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Not Annotated
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Carfecillin
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Not Annotated
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Carindacillin
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A penicillin antibiotic used to treat a variety of infections, but is no longer marketed in the USA.
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Cefacetrile
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Cefamandole
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A beta-lactam antibiotic used in the treatment of various infections caused by susceptible strains of bacteria, such as lower respiratory infections, urinary tract infections, skin infections, and bone and joint infections.
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Cefamandole nafate
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A second generation cephalosporin indicated in the prevention of infections during surgery.
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Cefatrizine
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Not Annotated
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Cefazedone
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Not Annotated
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Cefditoren
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A broad-spectrum third-generation cephalosporin antibiotic typically used to treat bacterial infections of the skin and respiratory tract.
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Cefetamet
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Not Annotated
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Cefetamet pivoxil
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Cefetamet pivoxil is under investigation in clinical trial NCT04664803 (Safety and Efficacy of Cefecin Tab. in Patients With Acute Sinusitis).
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Cefiderocol
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A cephalosporin antibiotic used in complicated urinary tract infections.
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Cefminox
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Cefminox (INN) is a second generation cephalosporin antibiotic. It is approved for use in Japan.
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Cefonicid
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For the treatment of bacterial infections caused by susceptible microorganisms.
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Cefoperazone
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A broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections in various locations, including the respiratory tract, abdomen, skin, and female genital tracts.
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Ceforanide
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For the treatment of infections caused by susceptible organisms.
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Cefotiam
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A cephalosporin antibiotic used to treat a variety of bacterial infections.
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Cefozopran
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Not Annotated
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Cefpiramide
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For treatment of severe infections caused by susceptible bacteria such as P. aeruginosa.
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Cefpirome
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An antibiotic indicated in the treatment of a wide variety of infections in the body.
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Cefsulodin
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Not Annotated
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Ceftaroline fosamil
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An antibacterial agent used to treat various bacterial infections, such as acute bacterial skin and skin structure infections and community-acquired bacterial pneumonia.
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Ceftezole
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Not Annotated
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Ceftibuten
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A third-generation cephalosporin antibiotic commonly used in the treatment of acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsillitis.
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Ceftiofur
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Ceftiofur is a third generation cephalosporin antibiotic, first described in 1987, and now used in veterinary medicine. It is marketed by pharmaceutical company Zoetis as Excenel, and is the active…
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Ceftizoxime
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A third-generation cephalosporin antibiotic used in the treatment of various bacterial infections, including lower respiratory tract infection, urinary tract infection, and gonorrhea.
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Ceftobiprole
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A broad spectrum 5th-generation cephalosporin antibacterial indicated for certain kinds of pneumonia, bacteremia, and skin and skin structure infections, including those caused by MRSA.
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Ceftobiprole medocaril
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A broad spectrum 5th-generation cephalosporin antibacterial indicated for certain kinds of pneumonia, bacteremia, and skin and skin structure infections, including those caused by MRSA.
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Cenicriviroc
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Cenicriviroc has been used in trials studying the treatment of HIV-infection/AIDS, AIDS Dementia Complex, Nonalcoholic Steatohepatitis, Human Immunodeficiency Virus, and HIV-1-Associated Cognitive Motor Complex.
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Cephaloglycin
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For treatment of severe infections caused by susceptible bacteria.
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Cerulenin
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For use as a biochemical tool, Cerulenin is shown to cause dramatic weight loss in animals
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Cetalkonium
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An antiseptic used as a preservative or to treat certain topical infections.
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Cethromycin
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A ketolide antibiotic with broad-spectrum activity against Gram-positive, Gram-negative, and atypical bacteria that may be useful for treating several conditions including community-acquired pneumonia, inhalation anthrax, plague, and tularemia.
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Cetrimonium
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A compound that can be used as a topical antiseptic.
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Cetylpyridinium
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A compound used to reduce plaque and gingivitis, as well as whiten teeth.
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Cetyltrimethylammonium naproxenate
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An anti-inflammatory and antiseptic agent indicated to treat mouth inflammation and pain , including that caused by tooth extraction.
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Chelerythrine
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A benzophenanthridine alkaloid evaluated as a kinase-inhibitor.
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Chloramphenicol succinate
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A broad-spectrum antibiotic agent used for the treatment of acute and severe infections caused by susceptible bacterial strains.
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Chlorhexidine
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An antiseptic used to sterilize for surgeries and in healthcare practice, to reduce pocket depth in periodontitis, and to treat gingivitis.
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Chlorine dioxide
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Chlorine Dioxide has been used in trials studying the treatment of Halitosis.
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Chloroquine
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An antimalarial drug used to treat susceptible infections with P. vivax, P. malariae, P. ovale, and P. falciparum. It is also used for second line treatment for rheumatoid arthritis.
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Chloroxine
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An antibacterial agent used for the treatment of dandruff and mild to moderately severe seborrheic dermatitis of the scalp.
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Chloroxylenol
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An antimicrobial used to treat cuts, bites, stings, abrasions, and used as an antiseptic hand cleaner.
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Chlorproguanil
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Chlorproguanil has been used in trials studying the treatment of MALARIA. It is a dichloro-derivative of chloroguanide.
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Chlorquinaldol
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Chlorquinaldol was used historically as a topical antiseptic agent for skin infections. It maintains use in European countries as a combination vaginal tablet with promestriene for use in the treatment…
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Chlortetracycline
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The first tetracycline antibiotic most commonly used for veterinary purposes.
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Ciclopirox
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A broad-spectrum topical antifungal agent used to treat mild to moderate onychomycosis of fingernails and toenails in immunocompetent patients.
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Cidofovir
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An antiviral agent used to treat Cytomegalovirus (CMV) retinitis in patients with AIDS.
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Cinoxacin
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For the treatment of initial and recurrent urinary tract infections in adults caused by the following susceptible microorganisms: Escherichia coli, Proteus mirabilis, Proteus vulgaris, Klebsiella species (including K. pneumoniae), and…
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Ciprofloxacin
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A second generation fluoroquinolone used to treat various susceptible bacterial infections.
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Clevudine
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Investigated for use/treatment in hepatitis (viral, B).
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Clinafloxacin
|
Clinafloxacin is a fluoroquinolone antibacterial currently under research. It has been proven to present good antibiotic properties. However, its approval and release have been halted due to the presence of…
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Clindamycin
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A lincosamide antibiotic used to treat serious infections caused by susceptible anaerobic, streptococcal, staphylococcal, and pneumococcal bacteria.
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Clioquinol
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An antifungal cream used to treat a variety of fungal infections.
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Clofazimine
|
A riminophenazine antimycobacterial used to treat leprosy.
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Clorsulon
|
Not Annotated
|
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Clotrimazole
|
A topical broad-spectrum antifungal agent used for the treatment of a wide variety of dermatophyte infections and candidiasis.
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Cobicistat
|
A CYP3A inhibitor used to increase the systemic exposure of atazanavir or darunavir in combination with other antiretroviral agents in the treatment of HIV-1 infection.
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Colistin
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A polymyxin antibiotic used to treat bacterial infections caused by susceptible Gram negative bacteria.
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Concanamycin A
|
Concanamycin A is an H+-ATPase (vacuolar) inhibitor.
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Cordycepin
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Cordycepin has been used in trials studying the treatment of Leukemia.
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Coumaphos
|
This drug is a fat-soluble phosphorothioate agent that kills both insects and mites. It is non-volatile in nature and is well known by a variety of names as such a…
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CRS-3123
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CRS3123 has been used in trials studying the treatment of Clostridial Infection and Clostridium Difficile Colitis.
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Cyclacillin
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For the treatment of bacterial infections caused by susceptible organisms.
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Cycloguanil
|
Cycloguanil is the active metabolite of proguanil.
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Cycloserine
|
A broad-spectrum antibiotic used in the treatment of tuberculosis and certain urinary tract infections (UTI).
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Cytarabine
|
A pyrimidine nucleoside analogue used to treat acute non-lymphocytic leukemia, lymphocytic leukemia, and the blast phase of chronic myelocytic leukemia.
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Dactinomycin
|
An actinomycin used to treat a wide variety of cancers.
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Dalfopristin
|
An antibiotic used with quinupristin to treat severe or life-threatening infections of vancomycin-resistant Enterococcus faecium (VREF), and skin infections caused by methicillin susceptible staphylococcus aureus or streptococcus pyogenes.
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Danofloxacin
|
Danofloxacin is an antibiotic agent from the family of the fluoroquinolones used in veterinary medicine.
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Dapivirine
|
Dapivirine has been investigated for the prevention of HIV-1 Infections and Topical Penile Exposures.
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Dapsone
|
A sulfone drug used to treat acne vulgaris, Hansen’s disease, and dermatitis herpetiformis.
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Daptomycin
|
A cyclic lipopeptide antibiotic used to treat complicated skin and skin structure infections by susceptible Gram-positive bacteria and bacteremia due to Staphylococcus aureus.
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Darunavir
|
A HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies.
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Decamethoxine
|
Not Annotated
|
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Decoquinate
|
Decoquinate is used in veterinary to delay the growth and reproduction of coccidian parasites.
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Delafloxacin
|
A fluoroquinolone antibiotic used to treat skin and skin structure infections.
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Delavirdine
|
A non-nucleoside reverse transcriptase inhibitor used to treat HIV infection.
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Delpazolid
|
Delpazolid (LCB01-0371) is under investigation in clinical trial NCT01554995 (A Clinical Study, Randomized, Double-blind, Placebo-controlled, Single Dose Study).
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Demeclocycline
|
A tetracycline antibiotic used to treat a wide variety of susceptible bacterial infections.
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Dequalinium
|
A quaternary ammonium cation antimicrobial agent used to treat common infections of the mouth and throat, as well as vaginal candidiasis.
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Dexelvucitabine
|
Dexelvucitabine has been used in trials studying the treatment of HIV Infections and Human Immunodeficiency Virus.
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Dibekacin
|
Dibekacin is an aminoglycoside antibiotic marketed in Japan .
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|
Dibrompropamidine
|
Not Annotated
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Dichlorophen
|
Dichlorophen is an antimicrobial agent shown to exert activity against cestodes, protozoa, fungi, and bacteria. It is often combined with toluene to remove parasites including ascarids, tapeworm, and hookworm from…
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Dichlorvos
|
Dichlorvos or 2,2-dichlorovinyl dimethyl phosphate is a drug of the organophosphate class, frequently used as an insecticide for the control of indoor pests and for the protection of stored products…
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Diclazuril
|
Diclazuril is a coccidiostat.
|
|
Didanosine
|
A reverse transcriptase inhibitor used to treat HIV.
|
|
Dideoxyadenosine
|
Not Annotated
|
|
Diethylcarbamazine
|
An anthelmintic used to treat filarial infections like Wuchereria bancrofti and Loa loa.
|
|
Dihydrostreptomycin
|
Dihydrostreptomycin is an aminoglycoside antibiotic. In humans, the use of dihydrostreptomycin has been associated with ototoxicity. The FDA withdrew its approval for the use of all drug products containing dihydrostreptomycin…
|
|
Diiodohydroxyquinoline
|
Used in the treatment of amoebiasis.
|
|
Diloxanide
|
Diloxanide is used alone as a primary agent in the treatment of asymptomatic (cyst passers) intestinal amebiasis caused by Entamoeba histolytica. Diloxanide may also be used concurrently, or sequentially, with…
|
|
Diloxanide furoate
|
Diloxanide is used alone as a primary agent in the treatment of asymptomatic (cyst passers) intestinal amebiasis caused by Entamoeba histolytica. Diloxanide may also be used concurrently, or sequentially, with…
|
|
Diminazene
|
Diminazene, also known as Diminazine, 4,4′-(Diazoamino)benzamidine, 4,4′-(1-triazene-1,3-diyl)bis-benzenecarboximidamide, diminazine aceturate, or Diminazene aceturate, is a trypanocidal agent. Major brands of Diminazene are Berenil, Pirocide, Ganasag, and Azidin. This substance is a…
|
|
Dirithromycin
|
An antibiotic used to treat a variety of respiratory, skin, and other infections.
|
|
Distearyldimonium
|
Not Annotated
|
|
Dithiazanine
|
Dithiazanine is a highly potent anthelmintic, introduced in 1959 for the treatment of strongyloid worms and whipworms. However, its use is severely limited due to its toxicity. Dithiazanine iodide was…
|
|
Ditiocarb
|
A chelating agent that has been used to mobilize toxic metals from the tissues of man and experimental animals. It is the main metabolite of DISULFIRAM.
|
|
Ditiocarb zinc
|
Ditiocarb Zinc is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6…
|
|
Docosanol
|
An antiviral used to treat orofacial herpes sores.
|
|
Dolutegravir
|
An antiviral agent used for the treatment of HIV-1 infections in combination with other antiretroviral agents.
|
|
Doramectin
|
Doramectin is a veterinary drug approved by the Food and Drug Administration for the treatment of parasites such as gastrointestinal roundworms, lungworms, eyeworms, grubs, sucking lice and mange mites in…
|
|
Doxycycline
|
A tetracycline antibiotic used to treat a wide variety of bacterial infections.
|
|
Drotrecogin alfa
|
A form of recombinant activated human protein C used to reduce mortality in patients with severe sepsis by inhibiting coagulation Factors V and VIII.
|
|
Durlobactam
|
A non-beta-lactam, beta-lactamase inhibitor used to treat hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia.
|
|
Duvoglustat
|
An alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity.
|
|
Ecabet
|
For the treatment of reflux oesophagitis and peptic ulcer disease.
|
|
Echinomycin
|
Echinomycin is a cytotoxic polypeptide quinoxaline antibiotic isolated from Streptomyces echinatus that binds to DNA and inhibits RNA synthesis.
|
|
Econazole
|
A topical antifungal used to treat tinea pedis, tinea cruris, tinea corporis, cutaneous candidiasis and tinea versicolor.
|
|
Edoxudine
|
A deoxythymidine analog used to treat herpetic keratitis.
|
|
Efavirenz
|
A non-nucleoside reverse transcriptase inhibitor used to treat HIV infection or prevent the spread of HIV.
|
|
Efinaconazole
|
An antifungal agent used to treat onychomycosis, a fungal infection of the nail.
|
|
Eflornithine
|
An ornithine decarboxylase inhibitor used to prevent relapse of high-risk neuroblastoma in pediatric and adult patients
|
|
Efrotomycin
|
Not Annotated
|
|
Efungumab
|
Efungumab is under investigation in clinical trial NCT00217815 (Preliminary Study of Mycograb and Docetaxel in Advanced Breast Cancer).
|
|
Elsulfavirine
|
Elsulfavirine is under investigation in clinical trial NCT03706898 (Study to Evaluate the Safety and PK of Elpida® in Healthy Subjects and Patients With Hepatic Impairment and to Assess the Impact…
|
|
Elvitegravir
|
An antiretroviral agent used in combination with other antiretrovirals for the treatment of HIV-1 infection in antiretroviral treatment-experienced adults.
|
|
Elvucitabine
|
Investigated for use/treatment in hepatitis (viral, B) and HIV infection.
|
|
Emetine
|
Not Annotated
|
|
Emivirine
|
Emivirine has been used in trials studying the treatment of HIV Infections.
|
|
Emodepside
|
Emodepside is an anthelmintic drug that is effective against a number of gastrointestinal nematodes, is licensed for use in cats and belongs to the class of drugs known as the…
|
|
Emtricitabine
|
A nucleoside reverse transcriptase inhibitor used for the treatment and prophylaxis of HIV.
|
|
Enfuvirtide
|
An HIV-1 gp41 fusion inhibitor used in patients experiencing HIV-1 replication who are already being treated with other anti-retrovirals.
|
|
Enmetazobactam
|
A beta-lactamase inhibitor used to treat complicated urinary tract infections in combination with cefepime.
|
|
Enoxacin
|
For the treatment of adults (≥18 years of age) with the following infections caused by susceptible strains of the designated microorganisms: (1) uncomplicated urethral or cervical gonorrhea due to Neisseria…
|
|
Enrofloxacin
|
Enrofloxacin is an antibiotic agent from the fluoroquinolone family produced by the Bayer Corporation. Enrofloxacin is approved by the FDA for its veterinary use. Due to the identification of fluoroquinolone-resistant…
|
|
Entecavir
|
A nucleoside analogue used in the treatment of chronic hepatitis B for patients with active viral replication, histological evidence of active disease, or persistent elevations in liver transaminases.
|
|
Enviomycin
|
Cyclic basic peptide related to viomycin. It is isolated from an induced mutant of Streptomyces griseoverticillatus var. tuberacticus and acts as an antitubercular agent with less ototoxicity than tuberactinomycin.
|
|
Epicillin
|
Not Annotated
|
|
Eprinomectin
|
Not Annotated
|
|
Ethacridine
|
Not Annotated
|
|
Ethambutol
|
An antituberculosis agent used in the prophylaxis and treatment of tuberculosis (TB).
|
|
Ethanol
|
For therapeutic neurolysis of nerves or ganglia for the relief of intractable chronic pain in such conditions as inoperable cancer and trigeminal neuralgia (tic douloureux), in patients for whom neurosurgical…
|
|
Ethionamide
|
A second line antitubercular agent used to treat tuberculosis when other treatments have failed.
|
|
Etofamide
|
Etofamide is used as an antiamoebic agent. Etofamide, under the brand name Kitnos, was marketed in Brazil by Pfizer but has been discontinued .
|
|
Etravirine
|
A non-nucleoside reverse transcriptase inhibitor (NNRTI) used in the treatment of HIV-1 infections in combination with other antiretroviral agents.
|
|
Eucalyptol
|
A common ingredient in mouthwash and cosmetics derived naturally from the eucalyptus plant that is frequently used to to improve symptoms of airway mucus hypersecretion.
|
|
Eugenol
|
A phenol used for the temporary relief of toothaches.
|
|
Famciclovir
|
A nucleoside analog DNA polymerase inhibitor used for the treatment of recurrent cold sores and genital herpes in healthy patients and patients with HIV, and to manage herpes zoster.
|
|
Favipiravir
|
An antiviral used to manage influenza, and that has the potential to target other viral infections.
|
|
Febantel
|
Not Annotated
|
|
Fenbendazole
|
Fenbendazole is a benzimidazole that presents a wide spectrum anthelmintic effect. It is used against a number of gastrointestinal parasites including giardia, roundworms, hookworms, whipworms, the Taenia genus of tapeworms,…
|
|
Fenticonazole
|
An imidazole antifungal used to treat a variety of topical fungal infections.
|
|
Fiacitabine
|
Fiacitabine has been used in trials studying the treatment of HIV Infections and Cytomegalovirus Infections.
|
|
Fialuridine
|
Fialuridine is under investigation in clinical trial NCT01337466 (Biodistribution and Dosimetry Evaluation of [124I]FIAU).
|
|
Fidaxomicin
|
A macrolide antibiotic used to treat diarrhea associated with Clostridium difficile infection.
|
|
Finafloxacin
|
Finafloxacin is indicated for the treatment of acute otitis externa (AOE) with or without an otowick, caused by susceptible strains of Pseudomonas aeruginosa and Staphylococcus aureus in patients age 1…
|
|
Fleroxacin
|
Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone.
|
|
Florfenicol
|
Florfenicol is a fluorinated synthetic analog of thiamphenicol.
|
|
Flubendazole
|
Flubendazole is an anthelmintic that is used to treat worm infection in humans. It is available OTC in Europe.
|
|
Flucytosine
|
An antifungal indicated only to treat severe infections throughout the body caused by susceptible strains of Candida or Cryptococcus.
|
|
Flumequine
|
Flumequine is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class used to treat bacterial infections.
|
|
Flutrimazole
|
A topical antifungal used to treat pityriasis capitis and seborrheic dermatitis.
|
|
Fomivirsen
|
Indicated for the local treatment of cytomegalovirus (CMV) retinitis in patients with acquired immunodeficiency syndrome (AIDS), when other therapy has been ineffective or is considered unsuitable [FDA Label, L1428].
|
|
Formaldehyde
|
A naturally occurring hazardous organic compound used as a preservative in animal feed, cosmetic products, laboratory procedures, disinfection, and home building products.
|
|
Fosamprenavir
|
An antiretroviral agent used for the treatment and postexposure prophylaxis of human immunodeficiency virus (HIV-1) infection.
|
|
Foscarnet
|
An antiviral used to treat CMV, HIV, and HSV infections.
|
|
Fosfomycin
|
A broad spectrum antibiotic used to treat uncomplicated urinary tract infections.
|
|
Fosmidomycin
|
Not Available
|
|
Fostemsavir
|
An antiretroviral HIV-1 attachment inhibitor targeted against the gp120 subunit within the HIV-1 gp160 envelope glycoprotein.
|
|
Framycetin
|
An aminoglycoside antibiotic used in various formulations and combinations with other agents to treat hemorrhoids, eye and ear infections, and to reduce nasal carriage of staphylococcus.
|
|
Fumagillin
|
Not Available
|
|
Furaltadone
|
Indicated in combination with other drugs for the treatment of otitis media and externa.
|
|
Furazidin
|
Not Annotated
|
|
Furazolidone
|
A drug for the treatment of infectious diarrhea.
|
|
Furvina
|
Furvina (G1) is an antimicrobial agent active against Gram-positive and Gram-negative bacteria, yeasts, and filamentous fungi. Furvina is marketed in Cuba as Dermofural®, an ointment containing G1 as the only…
|
|
Fusafungine
|
Fusafungine is an antibiotic from Fusarium lateririum, and is used for the treatment of respiratory infections.
|
|
Fusidic acid
|
A topical antibacterial agent used to prevent and treat mild to moderate skin infections caused by susceptible bacteria.
|
|
Galidesivir
|
Galidesivir is an adenosine analogue that has been investigated for use against Zaire Ebolavirus. In animal studies, galidesivir was effective in increasing the survival rates from infections caused by various…
|
|
Gamithromycin
|
Gamithromycin is an antibiotic used in cattle.
|
|
Ganciclovir
|
A DNA polymerase inhibitor used to treat cytomegalovirus and herpetic keratitis of the eye.
|
|
Garenoxacin
|
Investigated for use/treatment in bacterial infection.
|
|
Gatifloxacin
|
A fourth generation fluoroquinolone used to treat a wide variety of infections in the body.
|
|
GE-2270A
|
Not Available
|
|
Geldanamycin
|
Not Available
|
|
Gemifloxacin
|
A quinolone antibacterial agent used for the treatment of acute bacterial exacerbation of chronic bronchitis and mild to moderate community-acquired pneumonia caused by susceptible bacteria.
|
|
Geneticin
|
Geneticin (also known as G418) is an aminoglycoside antibiotic similar in structure to gentamicin B1, produced by Micromonospora rhodorangea. Geneticin blocks polypeptide synthesis by inhibiting the elongation step in both…
|
|
Gentian violet cation
|
An antiseptic violet dye used to prevent various infections, including fungal and bacterial infections.
|
|
Gimsilumab
|
Gimsilumab is under investigation in clinical trial NCT01357759 (Safety and Tolerability of MORAb-022 in Healthy and Rheumatoid Arthritis Subjects).
|
|
Glutaral
|
One of the protein CROSS-LINKING REAGENTS that is used as a disinfectant for sterilization of heat-sensitive equipment and as a laboratory reagent, especially as a fixative.
|
|
Glyphosate
|
Not Available
|
|
Gontivimab
|
Gontivimab is under investigation in clinical trial NCT03468829 (Efficacy and Safety of ALX-0171 in Adult Hematopoietic Stem Cell Transplant (HSCT) Recipients Who Present With Respiratory Syncytial Virus (RSV) Infection).
|
|
Gramicidin D
|
A bactericidal antibiotic used in the treatment of dermatological and ophthalmic infections.
|
|
Grazoprevir
|
An antiviral and NS3/4A protease inhibitor used to treat hepatitis C infections.
|
|
Grepafloxacin
|
A fluoroquinolone antibiotic used to treat various gram positive and gram negative bacterial infections.
|
|
Griseofulvin
|
An antifungal agent used to treat a variety of superficial tinea infections and fungal infections of the fingernails and toes.
|
|
GS 0573
|
Not Annotated
|
|
GS-441524
|
An experimental nucleoside analog antiviral investigated for its use in the treatment of Ebola and SARS-CoV-2 infections.
|
|
Hachimycin
|
Not Annotated
|
|
Halofantrine
|
An antimalarial used for the treatment of severe malaria.
|
|
Halofuginone
|
For the treatment of scleroderma, cancer, and restenosis.
|
|
Haloprogin
|
Used to treat fungal (Tinea) skin infections such as athlete’s foot, jock itch, ringworm, and tinea versicolor.
|
|
Hexachlorophene
|
A chlorinated bisphenol antiseptic used as a surgical scrub and skin cleanser.
|
|
Hexamidine
|
An antiseptic drug used for dermatomycoses and superficial bacterial infections alone or in combination with clotrimazole.
|
|
Hexetidine
|
An topical antiseptic agent used for disinfection and prevention of bacterial, fungal and yeast infections of the oral and vaginal mucosa.
|
|
Hexylresorcinol
|
An ingredient used to relieve irritation, pain, and prevent infection.
|
|
HIV Integrase Inhibitor
|
HIV Integrase Inhibitor is under investigation in clinical trial NCT00397566 (A Multiple Ascending Dose Study of BMS-707035 in HIV-1 Infected Subjects).
|
|
Homidium
|
Homidium is a group II compound with trypanocidal effects.
|
|
Honokiol
|
Honokiol is under investigation in clinical trial NCT00966953 (Development of Clinical Method to Determination Triclosan Retention in Plaque Following Brushing.).
|
|
HPA-23
|
HPA-23 is an investigational antiviral compound.
|
|
Human interferon beta
|
A polypeptide drug used in the treatment of relapsing forms of Multiple Sclerosis (MS).
|
|
Hycanthone
|
Potentially toxic, but effective antischistosomal agent, it is a metabolite of LUCANTHONE. Hycanthone was approved by the FDA in 1975 but is no longer used.
|
|
Hydrogen peroxide
|
A compound used as a disinfectant and sterilizer.
|
|
Hydroxychloroquine
|
An antimalarial medication used to treat uncomplicated cases of malaria and for chemoprophylaxis in specific regions. Also a disease modifying anti-rheumatic drug (DMARD) indicated for treatment of rheumatoid arthritis and lupus erythematosus.
|
|
Hydroxytyrosol
|
Hydroxytyrosol has been used in trials studying the prevention of Breast Cancer.
|
|
Hygromycin B
|
Hygromycin B is an aminoglycoside antibiotic produced by the bacterium Streptomyces hygroscopicus which kills bacteria, fungi and higher eukaryotic cells by inhibiting protein synthesis.
|
|
Hypericin
|
Hypericin is under investigation for the treatment of Cutaneous T-cell Lymphoma.
|
|
Hypochlorite
|
An antimicrobial used to treat and prevent infections of the skin and tissue.
|
|
Hypothiocyanite ion
|
Hypothiocyanite ion is under investigation in clinical trial NCT02598999 (Dose Escalation Study of ALX-009 in Healthy Men and Cystic Fibrosis (CF) and Non-CF Bronchiectasis Patients).
|
|
Ibacitabine
|
Not Annotated
|
|
Ibalizumab
|
A CD4-specific antibody used to treat HIV infections.
|
|
Ibrexafungerp
|
A triterpene antifungal indicated in the treatment of vulvovaginal candidiasis and prevention of recurrent vulvovaginal candidiasis in post-menarchal patients.
|
|
Idoxuridine
|
A pyrimidine analog antiviral used for the treatment of viral eye infections, including herpes simplex keratitis.
|
|
Imidocarb
|
Imidocarb is a urea derivative used in veterinary medicine as an antiprotozoal agent for the treatment of infection with Babesia and other parasites.
|
|
Imipenem
|
A carbapenem antibiotic normally administered with cilastatin to treat a variety of infections.
|
|
Indinavir
|
A protease inhibitor used to treat HIV infection.
|
|
Ingavirin
|
Ingavirin has been used in trials studying the treatment of Influenza and Common Cold.
|
|
Inosine pranobex
|
A medication used to treat subacute sclerosing panencephalitis.
|
|
Interferon alfa
|
An immunomodulator used to treat hepatitis B and C as well as certain types of cancer including cutaneous T-cell lymphoma and renal cell carcinoma.
|
|
Interferon alfa-1b
|
Not Annotated
|
|
Interferon alfa-2a
|
A form of recombinant human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C viruses.
|
|
Interferon alfa-2b
|
A form of recombinant human interferon used to treat hepatitis B and C infection, genital warts, hairy cell leukemia, follicular lymphoma, malignant melanoma, and AIDs-related Kaposi’s sarcoma.
|
|
Interferon alfacon-1
|
A recombinant interferon similar the interferon alfa subtype which is used to treat hepatitis C infections.
|
|
Interferon beta-1a
|
A form of recombinant human interferon used to slow disease progression and reduce the frequency of clinical symptoms in patients who have relapsing multiple sclerosis.
|
|
Interferon tau
|
Not Annotated
|
|
Iodine
|
An ingredient of nutritional supplements that is also used for disinfection.
|
|
Isatoic anhydride
|
Not Available
|
|
Isavuconazole
|
Indicated for patients 18 years of age and older for the treatment of invasive aspergillosis [FDA Label]. Indicated for patients 18 years of age and older for the treatment of…
|
|
Isavuconazonium
|
A triazole antifungal used for the treatment of invasive aspergillosis and mucormycosis.
|
|
Isepamicin
|
Not Annotated
|
|
Islatravir
|
Islatravir is under investigation in clinical trial NCT04233216 (Doravirine/islatravir (DOR/ISL) in Heavily Treatment-experienced (HTE) Participants for Human Immunodeficiency Virus Type 1 (HIV-1) Infection (MK-8591A-019)).
|
|
Isoconazole
|
An imidazole antifungal used for superficial skin and vaginal infections.
|
|
Isoniazid
|
An antibiotic used to treat mycobacterial infections; most commonly use in combination with other antimycobacterial agents for the treatment of active or latent tuberculosis.
|
|
Itraconazole
|
A triazole antifungal agent used to treat various fungal infections, such as blastomycosis and onychomycosis.
|
|
Ivermectin
|
An anti parasite medication used to treat head lice, onchocerciasis, strongyloidiasis, ascariasis, trichuriasis, and enterobiasis.
|
|
Josamycin
|
A macrolide antibiotic used for the treatment of various susceptible bacterial infections.
|
|
Ketoconazole
|
A broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections.
|
|
Kitasamycin
|
Kitasamycin is a macrolide antibiotic derived from Streptomyces kitasatoensis.
|
|
Lactoferrin
|
Lactoferrin is under investigation in clinical trial NCT03748043 (The Effectiveness of Lactoferrin in Treatment of Iron Deficiency Anemia in Children With Chronic Tonsillitis).
|
|
Lamivudine
|
A reverse transcriptase inhibitor used to treat HIV and hepatitis B infections.
|
|
Laninamivir
|
Laninamivir has been used in trials studying the treatment of Influenza.
|
|
Laninamivir octanoate
|
Laninamivir octanoate has been used in trials studying the treatment of Asthma.
|
|
Lapachone
|
Lapachone has been used in trials studying the treatment of Cancer, Carcinoma, Advanced Solid Tumors, Head and Neck Neoplasms, and Carcinoma, Squamous Cell.
|
|
Lasalocid
|
Lasalocid is an agent that presents antibacterial and coccidiostat activities. It is produced by strains of Streptomyces lasaliensis.
|
|
Latamoxef
|
Latamoxef is an oxacephem antibiotic usually grouped with the cephalosporins. It is used to treat bacterial infections. Latamoxef is primarily indicated in conditions like Bone and joint infection, GI infections,…
|
|
Lawsone
|
Not Available
|
|
Ledipasvir
|
A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents.
|
|
Lefamulin
|
A pleuromutilin antibacterial used to treat community-acquired bacterial pneumonia (CABP).
|
|
Leronlimab
|
A humanized monoclonal antibody being investigated
|
|
Letermovir
|
An antiviral medication used for prophylaxis in adult transplant recipients at risk of cytomegalovirus (CMV) infection and disease.
|
|
Levamisole
|
Levamisole is a nicotinic receptor agonist used to treat helminth infections and some skin infections.
|
|
Levofloxacin
|
A fluoroquinolone antibiotic used to treat infections caused by susceptible bacteria of the upper respiratory tract, skin and skin structures, urinary tract, and prostate, as well as for post-exposure treatment of inhaled anthrax and the plague.
|
|
Levonadifloxacin
|
Levonadifloxacin is under investigation in clinical trial NCT03405064 (Comparative Study of Levonadifloxacin (IV and Oral) With Linezolid (IV and Oral) in Acute Bacterial Skin and Skin Structure Infections (ABSSSI)).
|
|
LFF-571
|
LFF571 has been used in trials studying the treatment of Moderate Clostridium Difficile Infection.
|
|
Lincomycin
|
An antibiotic indicated only for the treatment of serious infections and is typically reserved for use in cases of penicillin allergy or where penicillin is inappropriate.
|
|
Linezolid
|
An oxazolidinone antibiotic used to treat infections by susceptible strains of aerobic Gram-positive bacteria.
|
|
Lobucavir
|
Lobucavir has been used in trials studying the treatment of HIV Infections and Cytomegalovirus Infections.
|
|
Lomefloxacin
|
A fluoroquinolone used to prevent and treat a wide variety of infections in the body.
|
|
Lonidamine
|
Investigated for use/treatment in benign prostatic hyperplasia, prostate disorders, and cancer/tumors (unspecified).
|
|
Lopinavir
|
An HIV-1 protease inhibitor used in combination with ritonavir to treat human immunodeficiency virus (HIV) infection.
|
|
Loracarbef
|
Used to treat upper respiratory tract bacterial infections, chronic bronchitis, pneumonia, sinusitis, pharyntitis and tonsillitis, skin absceses, urinary tract infections and pyelonephritis caused by E. coli, S. pyogenes, S. aureus,…
|
|
Lucanthone
|
Intended for use as a radiation sensitizer in the treatment of brain cancer.
|
|
Luliconazole
|
A topical antifungal agent used to treat fungal infections.
|
|
Lumefantrine
|
An antimalarial agent used in combination with artemether for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum.
|
|
Lymecycline
|
A tetracycline antibiotic used for the treatment of acne vulgaris and other susceptible infections.
|
|
Lysozyme
|
An enzyme indicated in the treatment of gastrointestinal disorders in infants, as well as Herpes zoster and Herpes simplex.
|
|
Macozinone
|
Macozinone is under investigation in clinical trial NCT03036163 (Phase 1 Study of PBTZ169).
|
|
Maduramicin
|
Maduramicin is an antiprotozoal agent used in veterinary medicine as prophylaxis against coccidiosis. It is a naturally occurring compound which was first isolated from the actinomycete, Actinomadura rubra.
|
|
Mafenide
|
An antimicrobial topical agent indicated for use as an adjunctive treatment to control bacterial infection when used under moist dressings over meshed autografts on excised burn wounds.
|
|
Maftivimab
|
Part of a product containing three monoclonal IgG1κ antibodies directed against the GP1,2 glycoprotein of Zaire ebolavirus. Together, these three antibodies act to neutralize viral particles and to recruit immune effectors for the destruction of both viral particles and infected cells.
|
|
Malachite Green
|
Not Available
|
|
Malacidin A
|
Malacidin A is being investigated for its antibiotic action and has potential for use as an antibacterial agent in the future .
|
|
Malacidin B
|
Malacidin B is being investigated for its antibiotic action and has potential for use as an antibacterial agent in the future .
|
|
Maltotetraose
|
Not Available
|
|
Mandelic acid
|
Mandelic acid is an approved aromatic, alpha hydroxy acid . Mandelic acid is used as an ingredient in cosmetics and drug products applied topically.
|
|
Maraviroc
|
A CCR5 co-receptor antagonist used with other antiretroviral medications to treat CCR5-tropic HIV-1 infection.
|
|
Marbofloxacin
|
Marbofloxacin is a carboxylic acid, part of the third generation of antibiotic fluoroquinolones. It is used in veterinary medicine. A formulation of marbofloxacin combined with clotrimazole and dexamethasone is available…
|
|
Maribavir
|
A cytomegalovirus (CMV) pUL97 kinase inhibitor used for the treatment of refractory post-transplant CMV infection.
|
|
Mebendazole
|
A benzimidazole anthelmintic used to treat helminth infections.
|
|
Meclocycline
|
A tetracycline antibiotic indicated in the treatment of susceptible skin infections, bacterial vaginitis, vulvovaginitis, and cervicitis.
|
|
Mefloquine
|
An antimalarial agent used in the prophylaxis and treatment of malaria caused by Plasmodium falciparum and Plasmodium vivax.
|
|
Meglumine antimoniate
|
Not Annotated
|
|
Melarsoprol
|
Melarsoprol is under investigation in clinical trial NCT00330148 (Randomized Clinical Trial of Three Drug Combinations for Late-Stage Gambiense Human African Trypanosomiasis).
|
|
Mepartricin
|
A medication indicated in the treatment of benign prostatic hyperplasia, vaginal candidiasis, or trichomoniasis.
|
|
Meplazumab
|
Meplazumab is a humanized anti-CD147 antibody being investigated as an add-on therapy in patients with COVID-19 pneumonia.
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|
Mercuric chloride
|
Mercury chloride (HgCl2) is a highly toxic compound that volatizes slightly at ordinary temperature and appreciably at 100 degrees C. It is corrosive to mucous membranes and used as a…
|
|
Metacycline
|
For the treatment of acute bacterial exacerbations of chronic bronchitis
|
|
Metampicillin
|
Metampicillin is a penicillin antibiotic prepared by the reaction of ampicillin with formaldehyde. It is hydrolysed in aqueous solution to form ampicillin. Hydrolysis is rapid under acid conditions like the…
|
|
Methenamine
|
A urinary tract antiseptic and antibacterial drug used for the prophylaxis and treatment of frequently recurring urinary tract infections requiring a long-term therapy.
|
|
Methylchloroisothiazolinone
|
Methylchloroisothiazolinone is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years…
|
|
Methylisothiazolinone
|
Not Annotated
|
|
Metisazone
|
Not Annotated
|
|
Metrifonate
|
Metrifonate or trichlorfon is an irreversible organophosphate acetylcholinesterase inhibitor. It is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate.
|
|
Metronidazole
|
A nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections.
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|
Mevastatin
|
Not used therapeutically due to its many side effects.
|
|
Mezlocillin
|
Used to treat serious gram–negative infections of the lungs, urinary tract, and skin.
|
|
Micafungin
|
An antifungal agent used for the treatment of candidemia, acute disseminated candidiasis, and certain other invasive Candida infections, and for the prophylaxis of Candida infections during stem cell transplantation.
|
|
Miconazole
|
An azole antifungal with broad-spectrum activity used to treat fungal infections affecting the vagina, mouth and skin, including candidiasis.
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|
Micronomicin
|
Micronomicin is an aminoglycoside antibiotic which is marketed in Japan, and sold under the brand names Sagamicin and Luxomicina.
|
|
Midecamycin
|
A macrolide antibiotic used to treat a variety of infections caused by susceptible bacteria.
|
|
Miglustat
|
A glucosylceramide synthase inhibitor used for the management of mild to moderate type I Gaucher disease for patients who are not candidates for whole enzyme replacement.
|
|
Milbemycin oxime
|
Not Annotated
|
|
Miltefosine
|
An antileishmanial agent used to treat leishmaniasis, a group of disease caused by parasites of the Leishmania type.
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|
Minocycline
|
A tetracycline analog used to treat a wide variety of infections in the body.
|
|
Miocamycin
|
Miocamycin is a macrolide type antimicrobial . This drug may be marketed in Japan for clinical use as it is listed in the Japanese pharmacopeia . It has shown to…
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|
Misonidazole
|
Misonidazole is under investigation in clinical trial NCT00038038 (Assessment of Head and Neck Tumor Hypoxia Using 18F-Fluoromisonidazole).
|
|
Mizoribine
|
Mizoribine has been investigated for the treatment of Rheumatoid Arthritis.
|
|
Modified vaccinia ankara
|
A live, non-replicating orthopoxvirus vaccine used to prevent smallpox, monkeypox, and other diseases caused by vaccinia virus.
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|
Molnupiravir
|
An orally bioavailable isopropylester cytidine analog used to treat COVID-19.
|
|
Monensin
|
Monensin is a polyether isolated from Streptomyces cinnamonensis that presents antibiotic properties. It is widely used in ruminant animal feeds.
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|
Moroxydine
|
Not Annotated
|
|
Moxidectin
|
Moxidectin is indicated for the treatment of river blindness, also called onchocerciasis, in patients aged 12 years and older. River blindness is caused by a parasitic worm Onchocerca volvulus and…
|
|
Moxifloxacin
|
A fluoroquinolone antibiotic used to treat various bacterial infections.
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|
Mupirocin
|
An antibacterial ointment used to treat impetigo and secondary skin infections caused by Staphylococcus aureus and Streptococcus pyogenes.
|
|
Murepavadin
|
Murepavadin is under investigation in clinical trial NCT02110459 (Pharmacokinetics and Safety of POL7080 in Patients With Renal Impairment).
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|
Mycophenolate mofetil
|
An inosine monophosphate dehydrogenase inhibitor used to prevent the rejection of kidney, heart, or liver transplants.
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|
Mycophenolic acid
|
An immunosuppressant used to prevent organ transplant rejections.
|
|
Myxothiazol
|
Not Available
|
|
N-chlorotaurine
|
Investigated for use/treatment in eye disorders/infections.
|
|
N-hydroxyguanidine
|
Not Available
|
|
Nadifloxacin
|
A topical fluoroquinolone used in the treatment of acne and topical bacterial skin infections.
|
|
Nafithromycin
|
Nafithromycin is under investigation in clinical trial NCT02903836 (Phase II Study of Oral Nafithromycin in CABP).
|
|
Naftifine
|
An antifungal agent used to treat infections of the Tinea, Trichophyton, and Epidermophyton species.
|
|
Nalidixic acid
|
A quinolone antibiotic used to treat urinary tract infections.
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|
Narasin
|
Narasin is an agent with coccidiostatic and antibacterial properties.
|
|
Natamycin
|
A macrolide antifungal used to treat fungal infections of the eye.
|
|
Nebularine
|
Not Available
|
|
Nelfinavir
|
A viral protease inhibitor used in the treatment of HIV infection.
|
|
Nemonoxacin
|
Investigated for use/treatment in bacterial infection and pneumonia.
|
|
Neoarsphenamine
|
Not Annotated
|
|
Netilmicin
|
An aminoglycoside used to treat a wide variety of infections in the body.
|
|
Netivudine
|
Netivudine has been used in trials studying the treatment of Chickenpox and HIV Infections.
|
|
Nevirapine
|
A non-nucleoside reverse transcriptase inhibitor used as part of a management regimen for HIV-1 virus infection.
|
|
Nicarbazin
|
Not Annotated
|
|
Niclosamide
|
An anthelmintic indicated in the treatment of beef, pork, fish, and dwarf tapeworm infections in adults and children.
|
|
Nifuratel
|
A nitrofuran derivative indicated in the treatment of leucorrhea, vulvovaginal infections, and urinary tract infections.
|
|
Nifuroxazide
|
An antibiotic indicated in the treatment of susceptible gastrointestinal infections.
|
|
Nifurtimox
|
An antiparasitic drug used for the treatment of Chagas disease (Trypanosoma cruzi infection).
|
|
Nifurtoinol
|
Not Annotated
|
|
Nigericin
|
A polyether antibiotic which affects ion transport and ATPase activity in mitochondria. It is produced by Streptomyces hygroscopicus. (From Merck Index, 11th ed)
|
|
Nikkomycin Z
|
Nikkomycin Z has been used in trials studying the treatment and basic science of Coccidioidomycosis.
|
|
Nimorazole
|
Nimorazole has been used in trials studying the treatment of Hypoxia, Radiotherapy, Hypoxic Modification, Gene Profile, Gene Signature, and Head and Neck Squamous Cell Carcinoma, among others.
|
|
Niridazole
|
Not Annotated
|
|
Nirmatrelvir
|
An oral protease inhibitor with emergency use authorization for the treatment of mild-to-moderate COVID-19.
|
|
Nisin Z
|
Nisin Z is under investigation in clinical trial NCT06097468 (Nisin in Oral Cavity Squamous Cell Carcinoma (OCSCC)).
|
|
Nitazoxanide
|
A thiazolide anti-infective used to treat infections by protozoa, helminths, anaerobic bacteria, microaerophilic bacteria, and viruses.
|
|
Nitrofural
|
A topical antibacterial for the prevention and treatment of bacterial infections of the skin.
|
|
Nitrofurantoin
|
An antibiotic used to treat urinary tract infections.
|
|
Nitroxoline
|
Nitroxoline is an antibiotic agent.
|
|
Norfloxacin
|
A broad-spectrum fluoroquinolone antibiotic with variable activity against gram-positive and gram-negative bacteria. Typically reserved for the treatment of UTIs due to accumulation in the urine.
|
|
Novobiocin
|
For the treatment of infections due to staphylococci and other susceptible organisms
|
|
Noxytiolin
|
Local antibacterial that probably acts by releasing formaldehyde in aqueous solutions. It is used for THERAPEUTIC IRRIGATION of infected body cavities – bladder, peritoneum, etc. and as a spray for…
|
|
Nystatin
|
A polyene ionophore antifungal used to treat cutaneous, mucocutaneous, and gastrointestinal mycotic infections, particularly those caused by Candida species.
|
|
Octenidine
|
An antiseptic agent used topically, on mucous membranes, and prior to surgery.
|
|
Odalasvir
|
Odalasvir has been used in trials studying the treatment of Hepatitis C, Chronic and Chronic Hepatitis C Infection.
|
|
Odesivimab
|
Part of a product containing three monoclonal IgG1κ antibodies directed against the GP1,2 glycoprotein of Zaire ebolavirus. Together, these three antibodies act to neutralize viral particles and to recruit immune effectors for the destruction of both viral particles and infected cells.
|
|
Ofloxacin
|
An antibacterial agent used for the treatment of bacterial infections in many parts of the body, including the respiratory tract, kidney, skin, soft tissue, and urinary tract.
|
|
Oleandomycin
|
Oleandomycin is a macrolide antibiotic, though it is less effective than erythromycin. It is synthesized from strains of Streptomyces antibioticus.
|
|
Olorofim
|
Olorofim is under investigation in clinical trial NCT03340597 (Assessment of Varying Oral Dosing Regimens for F901318 in Healthy Subjects).
|
|
Oltipraz
|
Oltipraz has been used in trials studying the treatment and prevention of Lung Cancer, Liver Fibrosis, Liver Cirrhosis, and Non-alcoholic Fatty Liver Disease.
|
|
Omoconazole
|
Not Annotated
|
|
Ornidazole
|
A nitroimidazole agent indicated in the treatment of infections such as trichomoniasis, amebiasis, and giardiasis.
|
|
Oseltamivir
|
A neuraminidase inhibitor used in the prophylaxis and treatment of influenza.
|
|
Oseltamivir acid
|
Not Available
|
|
Oxamniquine
|
For treatment of Schistosomiasis caused by Schistosoma mansoni
|
|
Oxantel
|
An antihelminthic indicated in the treatment of ascaris, trichocephaliasis, and oxyuriasis infections.
|
|
Oxfendazole
|
Oxfendazole is a sulfoxide metabolite of fenbendazole. This benzimidazole antihelminthic protects livestock from roundworm. strongyles, and pinworn.
|
|
Oxibendazole
|
Investigated for use/treatment in infectious and parasitic disease (unspecified) and pediatric indications.
|
|
Oxiconazole
|
A topical antifungal used to treat a variety of dermatophyte infections.
|
|
Oxolinic acid
|
Not Annotated
|
|
Oxymatrine
|
Oxymatrine is under investigation in clinical trial NCT02202473 (Oxymatrine Plus Lamivudine Combination Therapy Versus Lamivudine Monotherapy for Chronic Hepatitis B Infected Subjects).
|
|
Oxytetracycline
|
A tetracycline antibiotic used to treat a wide variety of susceptible bacterial infections.
|
|
Ozenoxacin
|
A quinolone antibiotic used to treat impetigo caused by susceptible bacteria.
|
|
p-Coumaric acid
|
Not Available
|
|
Pafuramidine
|
Investigated for use/treatment in pneumonia, trypanosomiasis, malaria, HIV infection, and infectious and parasitic disease (unspecified).
|
|
Palivizumab
|
A monoclonal anti respiratory syncytial virus F protein antibody used to prevent serious sequelae caused by respiratory syncytial virus infection in pediatric patients.
|
|
Palmidrol
|
A cannabinoid receptor-inactive eCB-related molecule used as prophylactic in helping to prevent respiratory viral infection. Palmidrol is available for human use as a supplement (400 mg capsules) and as food…
|
|
Parachlorophenol
|
An antibacterial agent used to prevent infections in root canals.
|
|
Paromomycin
|
An aminoglycoside antibiotic used in the treatment of acute and chronic intestinal amebiasis, and as an adjunct for the management of hepatic coma.
|
|
Pazufloxacin
|
Pazufloxacin is under investigation in clinical trial NCT02592096 (Pazufloxacin Mesilate Ear Drops Clinical Trial Protocol).
|
|
Pefloxacin
|
An antibiotic used to treat a variety of bacterial infections.
|
|
Peginterferon alfa-2a
|
A modified form of recombinant human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C viruses.
|
|
Peginterferon alfa-2b
|
A purified form of human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C, genital warts, and some cancers.
|
|
Penciclovir
|
A topical nucleoside polymerase inhibitor used in the treatment of recurrent herpes labialis.
|
|
Penimepicycline
|
Penimepicycline is a tetracycline-class antibiotic. It is mentioned on List A produced by the Government of Canada, which is a list of antimicrobial active pharmaceutical ingredients . In the classification…
|
|
Pentamidine
|
An antifungal agent used to treat Pneumocystis pneumonia in patients infected with HIV.
|
|
Peracetic acid
|
A liquid that functions as a strong oxidizing agent. It has an acrid odor and is used as a disinfectant.
|
|
Peramivir
|
An intravenous antiviral agent used to treat acute uncomplicated influenza in patients aged 2 years and older who are shown to be symptomatic for no more than two days.
|
|
Pexiganan
|
Pexiganan is under investigation in clinical trial NCT01594762 (Pexiganan Versus Placebo Control for the Treatment of Mild Infections of Diabetic Foot Ulcers).
|
|
PF-232798
|
PF-232798 is under investigation in clinical trial NCT01140425 (Study To Evaluate The Effect Of A Multiple Oral Dose Of PF-00232798 On QT Intervals In Healthy Subjects).
|
|
Phenol
|
An antiseptic and disinfectant used in a variety of settings.
|
|
Phenothiazine
|
Phenothiazine (PTZ) is an organic thiazine compound.
|
|
Phenoxyethanol
|
An antiseptic used as a hand disinfectant or preservative in medications.
|
|
Phenoxymethylpenicillin
|
A penicillin antibiotic used to prevent and treat mild to moderately severe infections in the respiratory tract, skin, and soft tissues.
|
|
Phenylethyl alcohol
|
An antimicrobial, antiseptic, and disinfectant that is used also as an aromatic essence and preservative in pharmaceutics and perfumery.
|
|
Phosphonoacetic Acid
|
A simple organophosphorus compound that inhibits DNA polymerase, especially in viruses and is used as an antiviral agent. [PubChem]
|
|
Phosphoramidon
|
Not Available
|
|
Picloxydine
|
Not Annotated
|
|
Pipemidic acid
|
A quinolone antibiotic indicated in the treatment of susceptible urinary tract infections.
|
|
Piperaquine
|
For the treatment of uncomplicated Plasmodium falciparum infection in adults, children, and infants aged 6 months and up weighing over 5 kg [FDA Label]. Used in combination with DB11638.
|
|
Piperazine
|
A medication used to treat roundworm and pinworm.
|
|
Piromidic acid
|
Not Annotated
|
|
Pivampicillin
|
An ampicillin prodrug used to treat a variety of infections.
|
|
Pivmecillinam
|
A prodrug of the beta lactam antibiotic mecillinam, indicated for the treatment of uncomplicated urinary tract infections (UTIs).
|
|
Platensimycin
|
Not Available
|
|
Pleconaril
|
Investigated for use/treatment in upper respiratory infection.
|
|
Plerixafor
|
A CXCR4 antagonist used in combination with granulocyte-colony stimulating factor to mobilize hematopoietic stem cells to the peripheral blood for collection and autologous transplantation in patients with non-Hodgkin’s lymphoma and multiple myeloma.
|
|
Plumbagin
|
Plumbagin is a compound investigated for its anticancer activity. It has been found that it inactivates the Akt/NF-kB, MMP-9 and VEGF pathways.
|
|
Pocapavir
|
Not Annotated
|
|
Polihexanide
|
Polihexanide has been used in trials studying the treatment, prevention, and supportive care of Caries, Neoplasm, Skin Diseases, Nail Diseases, and Dental Plaque, among others.
|
|
Poloxalene
|
Ethylene oxide/propylene oxide copolymer is used as a food additive. It belongs to the family of Epoxides. These are compounds containing a cyclic ether with three ring atoms (one oxygen…
|
|
Polymyxin B
|
A polymyxin antibiotic used to treat a wide variety of infections in the body.
|
|
Posaconazole
|
A triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.
|
|
Potassium iodate
|
Not Annotated
|
|
Povidone-iodine
|
A topical antiseptic agent used for the treatment and prevention of infection in wounds.
|
|
Pradefovir
|
Pradefovir is a prodrug of adefovir.
|
|
Pradefovir mesylate
|
Investigated for use as a prodrug for Hepsera in treating hepatitis (viral, B).
|
|
Praziquantel
|
An anthelmintic medication used to treat parasitic worm infections such as schistosomiasis, clonorchiasis, and opisthorchiasis
|
|
Primaquine
|
An antimalarial indicated to prevent relapse of vivax malaria.
|
|
Pristinamycin
|
Not Annotated
|
|
Pritelivir
|
Pritelivir has been used in trials studying the prevention of HSV-2 and Genital Herpes.
|
|
Procaine benzylpenicillin
|
A local anesthetic and antibiotic combination for intramuscular injection to treat a variety of bacterial infections while reducing pain from a deep intramuscular injection.
|
|
Proflavine
|
A topical antiseptic agent used in wound dressings to prevent infections.
|
|
Proguanil
|
A medication indicated for prophylaxis and treatment of Plasmodium falciparum malaria.
|
|
Propamidine
|
Not Annotated
|
|
Propanoic acid
|
An antimicrobial food additive.
|
|
Propicillin
|
Not Annotated
|
|
Propiolactone
|
Propiolactone was used for vaccines, tissue grafts, surgical instruments, and enzymes, as a sterilant of blood plasma, water, milk and nutrient broth as a vapor-phase disinfectant in enclosed spaces. Its…
|
|
Protionamide
|
An antitubercular thioamide-derivative used in the treatment of multi-drug resistant (MDR) tuberculosis and leprosy.
|
|
Prulifloxacin
|
A broad-spectrum fluoroquinolone antibiotic used to treat a variety of susceptible bacterial infections.
|
|
Psoralen
|
Not Annotated
|
|
Puromycin
|
Puromycin is an antibiotic that prevents bacterial protein translation. It is utilized as a selective agent in laboratory cell cultures. Puromycin is toxic to both prokaryotic and eukaryotic cells, resulting…
|
|
Pyrantel
|
An anthelmintic used to treat helminth infections.
|
|
Pyrazinamide
|
An antituberculosis agent used as a component of tuberculosis (TB) treatment.
|
|
Pyrimethamine
|
An antiparasitic drug used in the prevention and treatment of toxoplasmosis and malaria.
|
|
Pyrithione
|
An antimicrobial agent used for the treatment of dandruff and seborrheic dermatitis.
|
|
Pyronaridine
|
A benzonaphthyridine derivative indicated in the treatment of acute malaria caused by P. falciparum or P. vivax in area with low rates of infection and low resistance to artemisinin.
|
|
Pyrrolnitrin
|
Not Annotated
|
|
Pyrvinium
|
An anthelmintic agent used for the treatment of pinworm infestations.
|
|
Quinacrine
|
For the treatment of giardiasis and cutaneous leishmaniasis and the management of malignant effusions.
|
|
Quinidine
|
A medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias.
|
|
Quinine
|
An alkaloid used to treat uncomplicated Plasmodium falciparum malaria.
|
|
Quinupristin
|
An antibiotic agent used in the treatment of serious vancomycin-resistant Enterococcus faecium bacteremia as well as complicated skin and skin structure infections.
|
|
R-82913
|
Not Available
|
|
Racivir
|
Racivir, also known as RCV, is an oxothiolane nucleoside reverse transcriptase inhibitor similar to emtricitabine and lamivudine. Racivir is a 50:50 mixture of emtricitabine and its positive enantiomer. Racivir has…
|
|
Radavirsen
|
Radavirsen is under investigation in clinical trial NCT01375985 (Safety Study of Single Administration Intravenous Treatment for Influenza).
|
|
Radezolid
|
Radezolid has been used in trials studying the treatment of Abscess, Bacterial Skin Diseases, Streptococcal Infections, Infectious Skin Diseases, and Staphylococcal Skin Infections, among others.
|
|
Radicicol
|
Not Available
|
|
Raltegravir
|
An antiretroviral agent used for the treatment of HIV infections in conjunction with other antiretrovirals.
|
|
Ramoplanin
|
For the treatment of bacterial infections.
|
|
Remdesivir
|
A nucleoside analog used to treat RNA virus infections including COVID-19.
|
|
Remestemcel-L
|
Indicated for in the management of acute Graft versus Host Disease (aGvHD) in pediatric patients. Acute GvHD should be refractory to treatment with systemic corticosteroid therapy and/or other immunosuppressive agents….
|
|
Resorcinol
|
Contemporary therapeutic uses for resorcinol primarily revolve around the use of the phenol derivative as an active ingredient in topical antiseptics [L2745, L2744, L40069, F61] or as topical antibacterial skin…
|
|
Retapamulin
|
A topical antibiotic agent used for the treatment of impetigo caused by methicillin-susceptible Staphylococcus aureus or Streptococcus pyogenes.
|
|
Rezafungin
|
An echinocandin antifungal indicated in patients over 18 years old who have limited or no alternative options for the treatment of candidemia and invasive candidiasis.
|
|
Ribavirin
|
A guanosine nucleoside used to treat some forms of Hepatitis C.
|
|
Ribavirin monophosphate
|
Not Annotated
|
|
Ribostamycin
|
A broad spectrum aminoglycoside antibiotic on the list of WHO critical antimicrobials for human medicine.
|
|
Ridinilazole
|
Ridinilazole is under investigation in clinical trial NCT02092935 (A Study of SMT19969 Compared With Vancomycin for the Treatment of Clostridium Difficile-Associated Diarrhoea (CDAD)).
|
|
Rifabutin
|
An antibiotic used to treat mycobacterium avium complex disease in patients with HIV.
|
|
Rifalazil
|
Investigated for use/treatment in atherosclerosis, bacterial infection, and peripheral vascular disease.
|
|
Rifampin
|
An antibiotic used alone or in combination with other antimicrobial drugs to treat tuberculosis and asymptomatic carriers of Neisseria meningitidis.
|
|
Rifamycin
|
An antibacterial used to treat traveler’s diarrhea.
|
|
Rifapentine
|
An antibiotic agent used in the treatment of pulmonary tuberculosis.
|
|
Rifaximin
|
A rifamycin-based non-systemic antibiotic used for the treatment of gastrointestinal bacterial infections, such as traveler’s diarrhea and irritable bowel syndrome, and reduction of overt hepatic encephalopathy recurrence in adults.
|
|
Rilpivirine
|
A non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with other antiretrovirals to specifically treat human immunodeficiency virus type 1 (HIV-1).
|
|
Rimantadine
|
An RNA synthesis inhibitor used to prevent influenza A infection.
|
|
Rintatolimod
|
Not Annotated
|
|
Ritonavir
|
An HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection.
|
|
Robenidine
|
Robenidine is identified as a coccidiostat drug, which slows both the growth and reproductive cycles of coccidian parasites. Robenidine is used to control coccidiosis, a lethal infection in poultry which…
|
|
Rolitetracycline
|
A broad-spectrum tetracycline antibiotic used in cases needing high concentrations or when oral administration is impractical.
|
|
Rosoxacin
|
For the treatment of bacterial infection of respiratory tract, urinary tract, GI, CNS and immuno compromised patients.
|
|
Rovafovir etalafenamide
|
Rovafovir etalafenamide is under investigation in clinical trial NCT03472326 (Efficacy of GS-9131 Functional Monotherapy in HIV-1-Infected Adults Failing a Nucleos(t)Ide Reverse Transcriptase Inhibitor-Containing Regimen).
|
|
Roxarsone
|
Roxarsone is an organoarsenic molecule added to poultry feed. The addition of this compound to poultry feed improves weight gain and feed efficiency as well as prevent the growth of…
|
|
Roxithromycin
|
An antibiotic used to treat a variety of susceptible bacterial infections.
|
|
Rupintrivir
|
Investigated for use/treatment in viral infection.
|
|
Ruzasvir
|
Ruzasvir has been used in trials studying the treatment of Hepatitis C, Hepatitis C, Chronic, and Hepatitis C Infection.
|
|
S-Nitrosoglutathione
|
Not Annotated
|
|
Salicylhydroxamic Acid
|
Not Available
|
|
Salicylic acid
|
An acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts.
|
|
Salinomycin
|
Not Annotated
|
|
Santonin
|
Santonin is a anthelmintic drug that was previously approved in the US to treat certain parasitic infections.
|
|
Saquinavir
|
An HIV protease inhibitor used in combination with other antiretroviral agents for the treatment of HIV-1 with advanced immunodeficiency.
|
|
Sarecycline
|
A tetracycline antibiotic used to treat inflammatory lesions of non-nodular moderate to severe acne vulgaris.
|
|
Secnidazole
|
A nitroimidazole antibiotic used to treat bacterial vaginosis.
|
|
Selamectin
|
Selamectin is a topical parasiticide and antihelminthic used on dogs and cats to treat and prevent infections of heartworms, fleas, ear mites, sarcoptic mange, and certain types of ticks in…
|
|
Seliciclib
|
Investigated for use/treatment in breast cancer, lung cancer, lymphoma (unspecified), multiple myeloma, leukemia (lymphoid), and cancer/tumors (unspecified).
|
|
Semzuvolimab
|
Semzuvolimab is under investigation in clinical trial NCT03149211 (To Investigate the Efficacy and Safety of UB-421 Monotherapy in HIV-1 Infected Adults).
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Sertaconazole
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A topical antifungal agent used in the treatment of interdigital tinea pedis in immunocompetent patients.
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Silver nitrate
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Silver nitrate is an inorganic compound with the chemical formula AgNO3. In its solid form, silver nitrate is coordinated in a trigonal planar arrangement. It is often used as a…
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Silver oxide
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Not Annotated
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Silver proteinate
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A nasal decongestant and antiseptic of the nasal and ear canals.
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Silver sulfadiazine
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A topical sulfonamide antibiotic that acts on the bacterial cell wall and cell membrane; approved for the treatment of burns.
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Simeprevir
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A direct-acting antiviral agent that inhibits HCV NS3/4A protease to treat chronic hepatitis C virus (HCV) infection in adults with HCV genotype 1 or 4.
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Sinefungin
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Sinefungin is a solid. This compound belongs to the purine nucleosides and analogues. These are compounds comprising a purine base attached to a sugar. The proteins that adenosyl-ornithine target include…
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Sirolimus
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An mTOR inhibitor immunosuppressant used to prevent organ transplant rejections, treat lymphangioleiomyomatosis, and treat adults with perivascular epithelioid cell tumors.
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Sisomicin
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Sisomicin has been used in trials studying the treatment of Pyoderma.
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Sitafloxacin
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A fluoroquinolone antibiotic indicated in the treatment of susceptible bacterial infections.
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Sodium bisulfite
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An ingredient in parenteral nutrition products for patients with severe liver disorders.
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Sodium borate
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No FDA- or EMA-approved therapeutic indications on its own.
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Sodium stibogluconate
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For the treatment of various types of a protozoal infection called leishmaniasis, which may result from sandfly bites in tropical and temperate parts of the world. Also investigated for use/treatment…
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Sofosbuvir
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A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents.
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Solithromycin
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Investigated for the treatment of community-acquired pneumonia (CAP).
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Sorivudine
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Sorivudine has been used in trials studying the treatment of Chickenpox and HIV Infections.
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Sotrovimab
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A monoclonal antibody for the treatment of mild-to-moderate COVID-19 in patients at increased risk for death or hospitalization.
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Sparfloxacin
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A fluoroquinolone antibiotic used to treat bacterial respiratory infections and sinusitis.
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Sparfosic acid
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Sparfosic acid is a solid. This compound belongs to the n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at the terminal nitrogen…
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Squalamine
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Investigated for use/treatment in ovarian cancer, lung cancer, and macular degeneration.
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Stavudine
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A dideoxynucleoside used in the treatment of HIV infection.
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Stepronin
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Strepronin is a mucolytic (expectorant) drug.
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Streptolydigin
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Streptolydigin is an antibiotic isolated from culture filtrates of Streptomyces lydicus. It is active against gram-postive bacteria except micrococci.
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Sulbactam
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An beta-lactamase inhibitor antibiotic combined with other antibiotics to treat a variety of susceptible bacterial infections.
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Sulbenicillin
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Not Annotated
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Sulconazole
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A topical antifungal agent used for the treatment of tinea cruris, tinea corporis, and tinea versicolor caused by susceptible fungal strains.
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Sulfacetamide
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A sulfonamide used to treat inflammatory ocular conditions and acne vulgaris.
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Sulfachlorpyridazine
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A sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine.
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Sulfadiazine
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A sulfonamide antibiotic used in a variety of infections, such as urinary tract infections, trachoma, and chancroid.
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Sulfadicramide
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Not Annotated
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Sulfadimethoxine
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For use in the treatment of infections.
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Sulfadoxine
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A long acting sulfonamide used for the treatment or prevention of malaria.
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Sulfaguanidine
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Not Annotated
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Sulfaisodimidine
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Sulfaisodimidine also called sulfisomidine is an antibacterial product that has been studied for the treatment of urinary tract infections in the 1950s, however, it is unclear whether this drug has…
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Sulfamerazine
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An antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections.
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Sulfameter
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Long acting sulfonamide used in leprosy, urinary, and respiratory tract infections.
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Sulfamethazine
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An antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections.
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Sulfamethizole
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A sulfonamide antibiotic used to treat a wide variety of susceptible bacterial infections.
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Sulfamethoxazole
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An oral sulfonamide antibiotic, given in combination with trimethoprim, used to treat a variety of infections of the urinary tract, respiratory system, and gastrointestinal tract.
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Sulfamethoxypyridazine
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A sulphonamide antibiotic indicated in the treatment of gonorrhea, inflammation, urinary tract ulcers, and bronchitis.
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Sulfametopyrazine
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An antibiotic used in the treatment or prevention of bacterial infections and malaria.
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Sulfamoxole
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For the treatment of bacterial infection.
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Sulfanilamide
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A sulfonamide anti-infective used to treat vulvovaginal candidiasis caused by Candida albicans.
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Sulfaphenazole
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For the treatment bacterial infections.
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Sulfapyridine
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A sulfonamide antibiotic used to treat dermatitis herpetiformis, benign mucous membrane pemphigoid and pyoderma gangrenosum.
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Sulfaquinoxaline
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Sulfaquinoxaline is a veterinary medicine which can be given to cattle and sheep to treat coccidiosis.It is available in Pakistan with Sanna Laboratories in combination with Amprolium and Vitamin K…
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Sulfathiazole
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Sulfathiazole is effective against a wide range of gram positive and gram negative pathogenic microorganisms. Although no longer used in humans, it is used in cattle.
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Sulfisoxazole
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A sulfonamide antibiotic used with other antibiotics to prevent and treat a variety of bacterial infections.
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Sultamicillin
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A mutual prodrug of ampicillin and sulbactam useful in the treatment of infections caused by beta-lactamase-producing bacteria.
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Suramin
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For treatment of human sleeping sickness, onchocerciasis and other diseases caused by trypanosomes and worms.
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Tafenoquine
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An antiparasitic agent used for the treatment and prevention of relapse of Vivax malaria.
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Talampicillin
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Not Annotated
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Tanshinone I
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Not Annotated
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Taribavirin
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Investigated for use/treatment in hepatitis (viral, C).
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Taurolidine
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An antimicrobial derivative of taurine used for prophylaxis of catheter-related infections.
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Tavaborole
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An antifungal agent used to treat onychomycosis, a fungal infection of the nail.
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Tea tree oil
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Indicated for topical use to help protect against infection in minor cuts, scrapes, and burns. No FDA-approved therapeutic indications.
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Tecovirimat
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An antiviral medication used to treat smallpox, monkeypox, and cowpox.
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Tedizolid
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An oxazolidinone class antibiotic that inhibits bacterial protein synthesis and is proven to be effective in the treatment of certain Gram-positive bacterial infections.
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Tedizolid phosphate
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An oxazolidinone class antibiotic that inhibits bacterial protein synthesis and is proven to be effective in the treatment of certain Gram-positive bacterial infections.
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Telbivudine
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A thymidine nucleoside analog used for the treatment of chronic hepatitis B with clinical evidence of viral replication or persistent elevations in serum aminotransferases (ALT or AST).
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Telithromycin
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An ketolide used to treat community acquired pneumonia of mild to moderate severity.
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Temafloxacin
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For the treatment of lower respiratory tract infections, genital and urinary infections like prostatitis, and skin infections.
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Tenofovir
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A nucleotide analog indicated in the treatment of HIV infections.
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Tenofovir disoproxil
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A nucleotide analog reverse transcriptase inhibitor used in the treatment of Hepatitis B infection and used in the management of HIV-1 infection.
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Tenofovir exalidex
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Tenofovir exalidex is under investigation in clinical trial NCT01080820 (A Safety, Tolerability and Pharmacokinetic Study of a Single Dose of CMX157 in Healthy Volunteers).
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Terbinafine
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An allylamine antifungal used to treat dermatophyte infections of toenails and fingernails as well as other fungal skin infections.
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Terconazole
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An antifungal drug used in the treatment of vulvovaginal candidiasis.
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Tetracycline
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An antibiotic used to treat a wide variety of susceptible infections.
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Tetrandrine
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Not Annotated
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Tetroxoprim
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Not Annotated
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Thiabendazole
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A benzimidazole used in the treatment of strongyloides, cutaneous larva migrans, visceral larva migrans, and trichinosis infections.
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Thiamphenicol
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A semisynthetic derivative of chloramphenicol with a broad spectrum of antibacterial activity.
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Thiostrepton
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Thiostrepton is a natural cyclic oligopeptide antibiotic, derived from several strains of streptomycetes including Streptomyces azureus and Streptomyces laurentii. Thiostrepton is a natural product of the ribosomally synthesized and post-translationally…
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Thiosulfuric acid
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A sulfur donor used sequentially with sodium nitrite for the reversal of life-threatening acute cyanide poisoning. Also used to reduce the risk of ototoxicity associated with cisplatin.
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Thymol
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An essential oil found in various over-the-counter antibacterial and antifungal products.
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Tiamulin
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Tiamulin is a pleuromutilin antibiotic drug that is used in veterinary medicine particularly for pigs and poultry.
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Tigecycline
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A glycylcycline antibiotic used to treat a number of susceptible bacterial infections.
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Tilmicosin
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Tilmicosin is a macrolide antibiotic. It is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory disease associated with Mannheimia haemolytica.
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Tilorone
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Not Annotated
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Tinidazole
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A nitroimidazole used to treat trichomoniasis, giardiasis, amebiasis, and bacterial vaginosis.
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Tioconazole
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An imidazole antifungal used to treat vulvovaginal candidiasis.
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Tipranavir
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A protease inhibitor used to treat HIV-1 resistant to more than 1 protease inhibitor.
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Tipranavir C-14
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Tipranavir C-14 is under investigation in clinical trial NCT02253797 (Pharmacokinetics of Tipranavir/Ritonavir and Its Metabolites in Healthy Male Subjects).
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TJ003234
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Not Available
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Tolciclate
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Not Annotated
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Tolnaftate
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An antifungal agent used to treat various skin infections caused by fungi.
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Tosufloxacin
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Not Annotated
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Tosylchloramide
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A chlorinated disinfectant of the genitals and injured skin.
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Triacetin
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An acetylating agent indicated in the treatment of ringworm.
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Trichostatin A
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Not Available
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Triclabendazole
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An anthelmintic drug used to treat fascioliasis.
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Triclocarban
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An antibacterial agent used in liquid soaps and body washes.
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Triclosan
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An antimicrobial agent in clinical setting for disinfection, and prevention of spread and growth of bacteria, fungus, and mildew.
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Trifluridine
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A nucleoside metabolic inhibitor used to treat keratoconjunctivitis and epithelial keratitis caused by simplex virus, and as a part of chemotherapy for certain types of metastatic gastrointestinal cancers.
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Trimethoprim
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An antifolate antibiotic often used in combination with sulfamethoxazole to treat a number of infections, including those of the urinary tract, respiratory tract, and gastrointestinal tract.
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Trimetrexate
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A folate antagonist used for the treatment of moderate-to-severe Pneumocystis carinii pneumonia (PCP) in immunocompromised patients as an alternative therapy in combination with leucovorin.
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Troclosene
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Not Annotated
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Troleandomycin
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For the treatment of bacterial infection.
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Tromantadine
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Tromantadine is marketed as Viru-Merz in the Czech Republic . It is an antiviral used in the treatment of herpes zoster and simplex.
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Trovafloxacin
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An antibiotic used to treat gonorrhea and chlamydia.
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Troxacitabine
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Investigated for use/treatment in leukemia (myeloid).
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Tulathromycin A
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Tulathromycin is a macrolide antibiotic used to treat bovine respiratory disease in cattle and swine respiratory disease in pigs. It is marketed by Pfizer Inc. under the tradename Draxxin.
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Tunicamycin
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Tunicamycin is a mixture of homologous nucleoside antibiotics that inhibits the UDP-HexNAc: polyprenol-P HexNAc-1-P family of enzymes. One member of this family is the enzyme GlcNAc phosphotransferase (GPT), which catalyzes…
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Tylosin
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Tylosin is a bacteriostatic macrolide antibiotic and feed additive used in veterinary medicine. It has a broad spectrum of activity against Gram-positive organisms and a limited range of Gram-negative organisms….
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Tyrothricin
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A topical antibiotic with broad spectrum activity against Gram positive bacteria and some fungal infections.
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Ubenimex
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An adjuvant therapy used for acute and chronic myelonous leukemia, lung cancer and nasopharyngeal cancer. It is also used to treat hypercholesterolaemia.
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UC-781
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Investigated for use/treatment in HIV infection.
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Ulonivirine
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Not Available
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Uprifosbuvir
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Uprifosbuvir is under investigation in clinical trial NCT02332707 (Efficacy and Safety of Grazoprevir (MK-5172) and Uprifosbuvir (MK-3682) With Elbasvir (MK-8742) or Ruzasvir (MK-8408) for Chronic Hepatitis C Genotype (GT)1 and…
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Ursolic acid
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Not Annotated
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Vaborbactam
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A beta lactamase inhibitor used to treat complicated urinary tract infections.
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Valaciclovir
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An guanine nucleoside antiviral used to treat herpes exacerbations.
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Valganciclovir
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An antiviral medication used to treat cytomegalovirus (CMV) retinitis in patients diagnosed with acquired immunodeficiency syndrome (AIDS).
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Valinomycin
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A cyclododecadepsipeptide ionophore antibiotic produced by Streptomyces fulvissimus and related to the enniatins. It is composed of 3 moles each of L-valine, D-alpha-hydroxyisovaleric acid, D-valine, and L-lactic acid linked alternately…
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Velpatasvir
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A NS5A inhibitor used to treat chronic hepatitis C infections in patients without cirrhosis or with compensated cirrhosis.
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Vesatolimod
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Vesatolimod has been used in trials studying the treatment of Hepatitis B and Chronic Hepatitis B.
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Vesnarinone
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Vesnarinone has been used in trials studying the treatment of HIV Infections and Sarcoma, Kaposi.
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Vidarabine
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An antiviral agent used to treat various viral infections.
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Viomycin
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Viomycin is an essential component in the drug cocktail currently used to fight infections of Mycobacterium tuberculosis.
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Viral Macrophage-Inflammatory Protein
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Viral macrophage inflammatory protein-II (vMIP) is a highly basic protein and human chemokine analog encoded by human herpesvirus-8. The structure of vMIP consists of 71 residues and is a monomer…
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Virginiamycin
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Virginiamycin is a streptogramin antibiotic similar to pristinamycin and quinupristin/dalfopristin. It is a combination of pristinamycin IIA and virginiamycin S1. Virginiamycin is used in the fuel ethanol industry to prevent…
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Virginiamycin M1
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For the treatment of bacterial infections.
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VL-2397
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Not Annotated
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Voriconazole
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A triazole compound used to treat fungal infections.
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Wortmannin
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Wortmannin is a steroid metabolite of Penicillium funiculosum and Talaromyces wortmannii fungi. This drug acts as a nonspecific, covalent inhibitor of phosphoinositide 3-kinase enzymes (PI3Ks).
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Yimitasvir
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Not Available
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Zalcitabine
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A dideoxynucleoside used to treat HIV.
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Zanamivir
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A neuraminidase inhibitor used to treat influenza A and B.
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Zansecimab
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Zansecimab is under investigation in clinical trial NCT04342897 (A Study of LY3127804 in Participants With COVID-19).
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Zidovudine
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A dideoxynucleoside used in the treatment of HIV infection.
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Ziresovir
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Ziresovir is under investigation in clinical trial NCT03699202 (Anti-RSV Study in Chinese Patients (ASCENT)).
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Zoalene
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Dinitolmide is a fodder additive for prophylaxis against coccidiosis infections in poultry.
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