ANTI-INFECTIVE AGENTS

Drug

Description

2-deoxyglucose

As of July 2013, there is no approved therapeutic indication for 2-deoxyglucose. 2-deoxyglucose may have several potential indications as an adjunct to chemotherapy and radiotherapy in the treatment of solid…

2-mercaptobenzothiazole

Not Annotated

5′-Guanylylmethylenebisphosphonate

Not Available

5′-S-methyl-5′-thioadenosine

Not Available

Acemannan

Acemannan is under investigation in clinical trial NCT03250923 (Celagace™ Orarinse Solution for Treatment of Candidiasis).

Acetarsol

An anti infective used to treat a wide variety of infections in the body.

Acetic acid

An antimicrobial agent used to treat susceptible infections of the external auditory canal.

Acetylcysteine zinc

Not Available

Aconiazide

Not Annotated

Acriflavine

A topical antiseptic indicated in the treatment of infected wounds and for skin disinfection.

Acteoside

Acteoside is under investigation in clinical trial NCT02662283 (Validity and Security of Reh-acteoside Therapy for Patients of IgA Nephropathy).

Adafosbuvir

Adafosbuvir is under investigation in clinical trial NCT02894905 (A Study to Evaluate the Effect of Renal Impairment on the Pharmacokinetics of AL-335).

Adefovir

Not Annotated

Afabicin

Afabicin is under investigation in clinical trial NCT03723551 (Study to Assess Safety, Tolerability and Efficacy of Afabicin in The Treatment of Participants With Bone or Joint Infection Due to Staphylococcus).

Ajoene

Not Annotated

Albaconazole

Albaconazole has been used in trials studying the basic science of Onychomycosis.

Albendazole oxide

Not Annotated

Aldesleukin

A recombinant analog of interleukin-2 used to induce an adaptive immune response in the treatment of renal cell carcinoma.

Allicin

Allicin has been used in trials studying the treatment of Follicular Lymphoma.

Allopurinol riboside

Allopurinol riboside is a nucleoside analogue of allopurinol with a beta-D-ribofuranosyl moiety at the 1-position.

Alovudine

Investigated for use/treatment in HIV infection.

Alovudine F-18

Alovudine F-18 is under investigation in clinical trial NCT02819024 (Dexamethasone Effects in Patients With Refractory Non-Small Cell Lung Cancer Using FLT Positron Emission Tomography).

Aluminium acetotartrate

Not Annotated

Amantadine

A medication used to treat dyskinesia in Parkinson’s patients receiving levodopa, as well as extrapyramidal side effects of medications.

Aminacrine

A slow-acting germicide effective against bacteria and fungi which is included in drug formulations for its anti-septic properties.

Aminosalicylic acid

An aminosalicylate drug used to induce remission in ulcerative colitis.

Amithiozone

Amithiozone has been used in trials studying the treatment of Mycobacterium Avium-intracellulare Infection.

Ammonium trichlorotellurate

Ammonium trichlorotellurate is an investigational compound with anti-tumour and anti-inflammatory properties.

Amodiaquine

An antimalarial drug.

Amonafide

Investigated for use/treatment in breast cancer, ovarian cancer, and prostate cancer.

Amorolfine

A morpholine derivative commonly applied as a lacquer for onychomycosis but is also used for superficial dermatomycosis.

Amphomycin

Not Annotated

Amprenavir

A protease inhibitor used to treat HIV infection.

Amprolium

Amprolium is a coccidiostat used in poultry.

Andrographolide

Investigated for use/treatment in ulcerative colitis.

Anidulafungin

An antifungal used in the treatment of several types of candida infections.

Anisomycin

Anisomycin (sometimes known as flagecidin), is an antibiotic retrieved from the bacteria Streptomyces griseolus. This drug acts to inhibit bacterial protein and DNA synthesis.

Ansuvimab

A fully human monoclonal IgG1 antibody directed against the GP1,2 surface protein of Zaire ebolavirus that is an effective treatment for Ebola virus disease.

Anti-SARS-CoV-2 REGN-COV2

Anti-SARS-COV-2 REGN-COV2 is a combination of novel antibodies designed by Regeneron for both the prevention and treatment of SARS-COV-2, the virus that causes COVID-19. This drug is a combination of…

Antimony potassium tartrate

Antimony potassium tartrate is a schistosomicide possibly useful against other parasites. It has irritant emetic properties and may cause lethal cardiac toxicity among other adverse effects.

Aphidicolin

Aphidicolin is an antimitotic and antiviral metabolite of the mould Cephalosporium aphidicola. It inhibits DNA polymerase alpha and blocks DNA replication.[A259157, A259162]

Aplaviroc

Investigated for use/treatment in HIV infection.

Arbekacin

Arbekacin is used for the short term treatment of multi-resistant bacterial infections, such as methicillin-resistant Staphylococcus aureus (MRSA).

Arsanilic acid

An arsenical which has been used as a feed additive for enteric conditions in pigs and poultry. It causes blindness and is ototoxic and nephrotoxic in animals. [PubChem]

Artefenomel

Artefenomel has been investigated for the treatment of Malaria.

Artemisinin

A medication indicated in the treatment of malaria.

Artemotil

Artemotil, also known as β-arteether, is a semi-synthetic derivative of artemisinin and a fast acting blood schizonticide specifically indicated for the treatment of chloroquine-resistant Plasmodium falciparum malaria and cerebral malaria…

Artenimol

For the treatment of uncomplicated Plasmodium falciparum infection in adults, children, and infants aged 6 months and up weighing over 5 kg [FDA Label]. Used in combination with DB13941.

Artesunate

Artesunate is an artemesinin derivative indicated for the initial treatment of severe malaria.

Asiaticoside

Not Annotated

Astegolimab

Astegolimab is under investigation in clinical trial NCT04386616 (A Study to Evaluate the Safety and Efficacy of MSTT1041A (Astegolimab) or UTTR1147A in Patients With Severe COVID-19 Pneumonia).

Atevirdine

Atevirdine has been used in trials studying the treatment of HIV Infections.

Atoltivimab

Part of a product containing three monoclonal IgG1κ antibodies directed against the GP1,2 glycoprotein of Zaire ebolavirus. Together, these three antibodies act to neutralize viral particles and to recruit immune effectors for the destruction of both viral particles and infected cells.

Aurodox

Aurodox is an antibiotic obtained from a streptomyces variant considered as possibly effective against streptococcus pyogenes infections. It may promote growth in poultry.

Avdoralimab

Avdoralimab is under investigation in clinical trial NCT04333914 (Prospective Study in Patients With Advanced or Metastatic Cancer and Sars-cov-2 Infection).

Avilamycin

Not Annotated

AZD-5672

Azd5672 has been used in trials studying the basic science and treatment of Pharmacokinetics, Renal Impairment, and Rheumatoid Arthritis.

AZD7442

AZD7442 is a combination of SARS-CoV-2 antibodies (AZD8895 + AZD1061) currently undergoing phase I clinical trials for the prevention and treatment of COVID-19. It was developed by AstraZeneca with the…

Azidamfenicol

Not Annotated

Azlocillin

For the treatment of infections caused by Pseudomonas aeruginosa, Escherichia coli, and Haemophilus influenzae.

Azodicarbonamide

Not Annotated

Bacampicillin

An ampicillin prodrug used to treat various susceptible bacterial infections in the body, such as respiratory infections and skin and subcutaneous tissue infections.

Bafilomycin A1

The bafilomycins refer to a category of toxic macrolide antibiotics that are derivatives of Streptomyces griseus. These compounds all appear in the same fermentation and have similar biological activity. Bafilomycins…

Baloxavir

Baloxavir is under investigation in clinical trial NCT04327791 (Combination Therapy With Baloxavir and Oseltamavir 1 for Hospitalized Patients With Influenza (The COMBO Trial 1)).

Baloxavir marboxil

A polymerase acidic endonuclease inhibitor used to treat uncomplicated influenza.

Bambermycins

Bambermycins are antibiotic complexes which are retrieved from the organism, Streptomyces bambergiensis. They are used as an additive in food ingested by chickens and swine. The bambermycin complex of antibiotics…

Bamlanivimab

A neutralizing human IgG1κ monoclonal antibody against the SARS-CoV-2 spike (S) protein for use in patients aged 12 and over at high risk of developing severe COVID-19.

Basifungin

Basifungin, also known as aureuobacidin A, is a phosphorylceramide synthase inhibitor , .

Bedaquiline

A diarylquinoline antimycobacterial used in combination with other antibacterials to treat pulmonary multidrug resistant tuberculosis (MDR-TB).

Bekanamycin

An aminoglycoside antibiotic indicated in the treatment of eye infections.

Benzalkonium

An antiseptic agent used as a preservative in medications or as a disinfectant in cleaning products.

Benzethonium

A medication used as to clean hands and clean minor cuts and scrapes.

Benzimidazole

Not Available

Benznidazole

A trypanocidal agent used to treat Chagas disease.

Benzododecinium

Benzododecinium is used as an antiseptic/disinfectant compound. It has been marketed as a tincture for antiseptic product for wounds in the Czech Republic.

Benzoic acid

An antimicrobial food additive.

Bersacapavir

Bersacapavir is under investigation in clinical trial NCT03365947 (Study of ARO-HBV in Normal Adult Volunteers and Patients With Hepatitis B Virus (HBV)).

Besifloxacin

A fluoroquinolone antibiotic agent used for the treatment of bacterial conjunctivitis.

Betulinic Acid

Betulinic Acid has been used in trials studying the treatment of Dysplastic Nevus Syndrome.

Bibrocathol

Not Annotated

Bifonazole

An azole antifungal drug used to treat fungal skin infections, such as dermatomycosis.

Bismuth cation

Not Annotated

Bismuth subcitrate potassium

A colloid used for the treatment of peptic ulcer and gastro-esophageal reflux disease (GERD).

Bismuth subgallate

A medication used to deodorize flatulence and stools as well as hemostasis in soft tissue surgery.

Bithionol

Bithionol, formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause serious skin disorders. Approvals of the…

BMS-488043

Investigated for use/treatment in HIV infection.

BMS-955176

BMS-955176 is under investigation in clinical trial NCT02415595 (Dose-finding Study of BMS-955176 to Treat HIV-1 Infected Treatment-naive Adults).

Boric acid

No FDA- or EMA-approved therapeutic indications on its own.

Brefeldin A

A metabolite from Penicillium brefeldianum that exhibits a wide range of antibiotic activity.

Brilacidin

Brilacidin is under investigation for the supportive care of Mucositis, Stomatitis, Mouth Diseases, and Head and Neck Neoplasms.

Brilliant green cation

An ingredient used in topical medications to prevent infections of the umbilical cord.

Brincidofovir

An oral lipid prodrug of cidofovir used in the treatment of human smallpox disease.

Brivudine

A drug used to treat herpes zoster.

Brodimoprim

Not Annotated

Bronopol

An antimicrobial compound used as a biocide and preservative.

Broxuridine

Broxuridine has been used in trials studying the treatment of Leukemia, Stage I Prostate Cancer, Stage IIB Prostate Cancer, and Stage IIA Prostate Cancer.

Bunamidine

Bunamidine is a veterinary anti-platyhelmintic agent used for taenia infestations.

Butenafine

A topical antifungal used to treat tinea versicolor, tinea pedis, tinea cruris, and tinea corporis.

Cabotegravir

An HIV-1 integrase inhibitor used for treatment and pre-exposure prophylaxis of HIV-1 infection.

Cadexomer iodine

Not Annotated

Calanolide A

For use in combination treatment of HIV infection (AIDS).

Calcium sulfide

Not Annotated

Cambendazole

Not Annotated

Camphor

A compound used topically to help relieve pain and also as a topical antiseptic. May also be used in vaporizers to help suppress coughing. This medication should not be swallowed.

Candicidin

Used in the topical treatment of vulvovaginal candidiasis.

Capravirine

Investigated for use/treatment in acquired immune deficiency syndrome (AIDS) and aids-related infections and HIV infection.

Capric acid

Decanoic acid is a solid. This compound belongs to the straight chain fatty acids. These are fatty acids with a straight aliphatic chain. The proteins that decanoic acid targets include…

Carbamide peroxide

A medication used to loosen ear wax, whiten teeth, and clean oral wounds.

Carbendazim

Carbendazim has been used in trials studying the treatment of Lymphoma and Unspecified Adult Solid Tumor, Protocol Specific.

Carbocisteine

A expectorant mucolytic used in the relief of respiratory of COPD and other conditions associated with increased mucus viscosity.

Carbovir

Not Annotated

Carfecillin

Not Annotated

Carindacillin

A penicillin antibiotic used to treat a variety of infections, but is no longer marketed in the USA.

Cefacetrile

Cefamandole

A beta-lactam antibiotic used in the treatment of various infections caused by susceptible strains of bacteria, such as lower respiratory infections, urinary tract infections, skin infections, and bone and joint infections.

Cefamandole nafate

A second generation cephalosporin indicated in the prevention of infections during surgery.

Cefatrizine

Not Annotated

Cefazedone

Not Annotated

Cefditoren

A broad-spectrum third-generation cephalosporin antibiotic typically used to treat bacterial infections of the skin and respiratory tract.

Cefetamet

Not Annotated

Cefetamet pivoxil

Cefetamet pivoxil is under investigation in clinical trial NCT04664803 (Safety and Efficacy of Cefecin Tab. in Patients With Acute Sinusitis).

Cefiderocol

A cephalosporin antibiotic used in complicated urinary tract infections.

Cefminox

Cefminox (INN) is a second generation cephalosporin antibiotic. It is approved for use in Japan.

Cefonicid

For the treatment of bacterial infections caused by susceptible microorganisms.

Cefoperazone

A broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections in various locations, including the respiratory tract, abdomen, skin, and female genital tracts.

Ceforanide

For the treatment of infections caused by susceptible organisms.

Cefotiam

A cephalosporin antibiotic used to treat a variety of bacterial infections.

Cefozopran

Not Annotated

Cefpiramide

For treatment of severe infections caused by susceptible bacteria such as P. aeruginosa.

Cefpirome

An antibiotic indicated in the treatment of a wide variety of infections in the body.

Cefsulodin

Not Annotated

Ceftaroline fosamil

An antibacterial agent used to treat various bacterial infections, such as acute bacterial skin and skin structure infections and community-acquired bacterial pneumonia.

Ceftezole

Not Annotated

Ceftibuten

A third-generation cephalosporin antibiotic commonly used in the treatment of acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsillitis.

Ceftiofur

Ceftiofur is a third generation cephalosporin antibiotic, first described in 1987, and now used in veterinary medicine. It is marketed by pharmaceutical company Zoetis as Excenel, and is the active…

Ceftizoxime

A third-generation cephalosporin antibiotic used in the treatment of various bacterial infections, including lower respiratory tract infection, urinary tract infection, and gonorrhea.

Ceftobiprole

A broad spectrum 5th-generation cephalosporin antibacterial indicated for certain kinds of pneumonia, bacteremia, and skin and skin structure infections, including those caused by MRSA.

Ceftobiprole medocaril

A broad spectrum 5th-generation cephalosporin antibacterial indicated for certain kinds of pneumonia, bacteremia, and skin and skin structure infections, including those caused by MRSA.

Cenicriviroc

Cenicriviroc has been used in trials studying the treatment of HIV-infection/AIDS, AIDS Dementia Complex, Nonalcoholic Steatohepatitis, Human Immunodeficiency Virus, and HIV-1-Associated Cognitive Motor Complex.

Cephaloglycin

For treatment of severe infections caused by susceptible bacteria.

Cerulenin

For use as a biochemical tool, Cerulenin is shown to cause dramatic weight loss in animals

Cetalkonium

An antiseptic used as a preservative or to treat certain topical infections.

Cethromycin

A ketolide antibiotic with broad-spectrum activity against Gram-positive, Gram-negative, and atypical bacteria that may be useful for treating several conditions including community-acquired pneumonia, inhalation anthrax, plague, and tularemia.

Cetrimonium

A compound that can be used as a topical antiseptic.

Cetylpyridinium

A compound used to reduce plaque and gingivitis, as well as whiten teeth.

Cetyltrimethylammonium naproxenate

An anti-inflammatory and antiseptic agent indicated to treat mouth inflammation and pain , including that caused by tooth extraction.

Chelerythrine

A benzophenanthridine alkaloid evaluated as a kinase-inhibitor.

Chloramphenicol succinate

A broad-spectrum antibiotic agent used for the treatment of acute and severe infections caused by susceptible bacterial strains.

Chlorhexidine

An antiseptic used to sterilize for surgeries and in healthcare practice, to reduce pocket depth in periodontitis, and to treat gingivitis.

Chlorine dioxide

Chlorine Dioxide has been used in trials studying the treatment of Halitosis.

Chloroquine

An antimalarial drug used to treat susceptible infections with P. vivax, P. malariae, P. ovale, and P. falciparum. It is also used for second line treatment for rheumatoid arthritis.

Chloroxine

An antibacterial agent used for the treatment of dandruff and mild to moderately severe seborrheic dermatitis of the scalp.

Chloroxylenol

An antimicrobial used to treat cuts, bites, stings, abrasions, and used as an antiseptic hand cleaner.

Chlorproguanil

Chlorproguanil has been used in trials studying the treatment of MALARIA. It is a dichloro-derivative of chloroguanide.

Chlorquinaldol

Chlorquinaldol was used historically as a topical antiseptic agent for skin infections. It maintains use in European countries as a combination vaginal tablet with promestriene for use in the treatment…

Chlortetracycline

The first tetracycline antibiotic most commonly used for veterinary purposes.

Ciclopirox

A broad-spectrum topical antifungal agent used to treat mild to moderate onychomycosis of fingernails and toenails in immunocompetent patients.

Cidofovir

An antiviral agent used to treat Cytomegalovirus (CMV) retinitis in patients with AIDS.

Cinoxacin

For the treatment of initial and recurrent urinary tract infections in adults caused by the following susceptible microorganisms: Escherichia coli, Proteus mirabilis, Proteus vulgaris, Klebsiella species (including K. pneumoniae), and…

Ciprofloxacin

A second generation fluoroquinolone used to treat various susceptible bacterial infections.

Clevudine

Investigated for use/treatment in hepatitis (viral, B).

Clinafloxacin

Clinafloxacin is a fluoroquinolone antibacterial currently under research. It has been proven to present good antibiotic properties. However, its approval and release have been halted due to the presence of…

Clindamycin

A lincosamide antibiotic used to treat serious infections caused by susceptible anaerobic, streptococcal, staphylococcal, and pneumococcal bacteria.

Clioquinol

An antifungal cream used to treat a variety of fungal infections.

Clofazimine

A riminophenazine antimycobacterial used to treat leprosy.

Clorsulon

Not Annotated

Clotrimazole

A topical broad-spectrum antifungal agent used for the treatment of a wide variety of dermatophyte infections and candidiasis.

Cobicistat

A CYP3A inhibitor used to increase the systemic exposure of atazanavir or darunavir in combination with other antiretroviral agents in the treatment of HIV-1 infection.

Colistin

A polymyxin antibiotic used to treat bacterial infections caused by susceptible Gram negative bacteria.

Concanamycin A

Concanamycin A is an H+-ATPase (vacuolar) inhibitor.

Cordycepin

Cordycepin has been used in trials studying the treatment of Leukemia.

Coumaphos

This drug is a fat-soluble phosphorothioate agent that kills both insects and mites. It is non-volatile in nature and is well known by a variety of names as such a…

CRS-3123

CRS3123 has been used in trials studying the treatment of Clostridial Infection and Clostridium Difficile Colitis.

Cyclacillin

For the treatment of bacterial infections caused by susceptible organisms.

Cycloguanil

Cycloguanil is the active metabolite of proguanil.

Cycloserine

A broad-spectrum antibiotic used in the treatment of tuberculosis and certain urinary tract infections (UTI).

Cytarabine

A pyrimidine nucleoside analogue used to treat acute non-lymphocytic leukemia, lymphocytic leukemia, and the blast phase of chronic myelocytic leukemia.

Dactinomycin

An actinomycin used to treat a wide variety of cancers.

Dalfopristin

An antibiotic used with quinupristin to treat severe or life-threatening infections of vancomycin-resistant Enterococcus faecium (VREF), and skin infections caused by methicillin susceptible staphylococcus aureus or streptococcus pyogenes.

Danofloxacin

Danofloxacin is an antibiotic agent from the family of the fluoroquinolones used in veterinary medicine.

Dapivirine

Dapivirine has been investigated for the prevention of HIV-1 Infections and Topical Penile Exposures.

Dapsone

A sulfone drug used to treat acne vulgaris, Hansen’s disease, and dermatitis herpetiformis.

Daptomycin

A cyclic lipopeptide antibiotic used to treat complicated skin and skin structure infections by susceptible Gram-positive bacteria and bacteremia due to Staphylococcus aureus.

Darunavir

A HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies.

Decamethoxine

Not Annotated

Decoquinate

Decoquinate is used in veterinary to delay the growth and reproduction of coccidian parasites.

Delafloxacin

A fluoroquinolone antibiotic used to treat skin and skin structure infections.

Delavirdine

A non-nucleoside reverse transcriptase inhibitor used to treat HIV infection.

Delpazolid

Delpazolid (LCB01-0371) is under investigation in clinical trial NCT01554995 (A Clinical Study, Randomized, Double-blind, Placebo-controlled, Single Dose Study).

Demeclocycline

A tetracycline antibiotic used to treat a wide variety of susceptible bacterial infections.

Dequalinium

A quaternary ammonium cation antimicrobial agent used to treat common infections of the mouth and throat, as well as vaginal candidiasis.

Dexelvucitabine

Dexelvucitabine has been used in trials studying the treatment of HIV Infections and Human Immunodeficiency Virus.

Dibekacin

Dibekacin is an aminoglycoside antibiotic marketed in Japan .

Dibrompropamidine

Not Annotated

Dichlorophen

Dichlorophen is an antimicrobial agent shown to exert activity against cestodes, protozoa, fungi, and bacteria. It is often combined with toluene to remove parasites including ascarids, tapeworm, and hookworm from…

Dichlorvos

Dichlorvos or 2,2-dichlorovinyl dimethyl phosphate is a drug of the organophosphate class, frequently used as an insecticide for the control of indoor pests and for the protection of stored products…

Diclazuril

Diclazuril is a coccidiostat.

Didanosine

A reverse transcriptase inhibitor used to treat HIV.

Dideoxyadenosine

Not Annotated

Diethylcarbamazine

An anthelmintic used to treat filarial infections like Wuchereria bancrofti and Loa loa.

Dihydrostreptomycin

Dihydrostreptomycin is an aminoglycoside antibiotic. In humans, the use of dihydrostreptomycin has been associated with ototoxicity. The FDA withdrew its approval for the use of all drug products containing dihydrostreptomycin…

Diiodohydroxyquinoline

Used in the treatment of amoebiasis.

Diloxanide

Diloxanide is used alone as a primary agent in the treatment of asymptomatic (cyst passers) intestinal amebiasis caused by Entamoeba histolytica. Diloxanide may also be used concurrently, or sequentially, with…

Diloxanide furoate

Diloxanide is used alone as a primary agent in the treatment of asymptomatic (cyst passers) intestinal amebiasis caused by Entamoeba histolytica. Diloxanide may also be used concurrently, or sequentially, with…

Diminazene

Diminazene, also known as Diminazine, 4,4′-(Diazoamino)benzamidine, 4,4′-(1-triazene-1,3-diyl)bis-benzenecarboximidamide, diminazine aceturate, or Diminazene aceturate, is a trypanocidal agent. Major brands of Diminazene are Berenil, Pirocide, Ganasag, and Azidin. This substance is a…

Dirithromycin

An antibiotic used to treat a variety of respiratory, skin, and other infections.

Distearyldimonium

Not Annotated

Dithiazanine

Dithiazanine is a highly potent anthelmintic, introduced in 1959 for the treatment of strongyloid worms and whipworms. However, its use is severely limited due to its toxicity. Dithiazanine iodide was…

Ditiocarb

A chelating agent that has been used to mobilize toxic metals from the tissues of man and experimental animals. It is the main metabolite of DISULFIRAM.

Ditiocarb zinc

Ditiocarb Zinc is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6…

Docosanol

An antiviral used to treat orofacial herpes sores.

Dolutegravir

An antiviral agent used for the treatment of HIV-1 infections in combination with other antiretroviral agents.

Doramectin

Doramectin is a veterinary drug approved by the Food and Drug Administration for the treatment of parasites such as gastrointestinal roundworms, lungworms, eyeworms, grubs, sucking lice and mange mites in…

Doxycycline

A tetracycline antibiotic used to treat a wide variety of bacterial infections.

Drotrecogin alfa

A form of recombinant activated human protein C used to reduce mortality in patients with severe sepsis by inhibiting coagulation Factors V and VIII.

Durlobactam

A non-beta-lactam, beta-lactamase inhibitor used to treat hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia.

Duvoglustat

An alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity.

Ecabet

For the treatment of reflux oesophagitis and peptic ulcer disease.

Echinomycin

Echinomycin is a cytotoxic polypeptide quinoxaline antibiotic isolated from Streptomyces echinatus that binds to DNA and inhibits RNA synthesis.

Econazole

A topical antifungal used to treat tinea pedis, tinea cruris, tinea corporis, cutaneous candidiasis and tinea versicolor.

Edoxudine

A deoxythymidine analog used to treat herpetic keratitis.

Efavirenz

A non-nucleoside reverse transcriptase inhibitor used to treat HIV infection or prevent the spread of HIV.

Efinaconazole

An antifungal agent used to treat onychomycosis, a fungal infection of the nail.

Eflornithine

An ornithine decarboxylase inhibitor used to prevent relapse of high-risk neuroblastoma in pediatric and adult patients

Efrotomycin

Not Annotated

Efungumab

Efungumab is under investigation in clinical trial NCT00217815 (Preliminary Study of Mycograb and Docetaxel in Advanced Breast Cancer).

Elsulfavirine

Elsulfavirine is under investigation in clinical trial NCT03706898 (Study to Evaluate the Safety and PK of Elpida® in Healthy Subjects and Patients With Hepatic Impairment and to Assess the Impact…

Elvitegravir

An antiretroviral agent used in combination with other antiretrovirals for the treatment of HIV-1 infection in antiretroviral treatment-experienced adults.

Elvucitabine

Investigated for use/treatment in hepatitis (viral, B) and HIV infection.

Emetine

Not Annotated

Emivirine

Emivirine has been used in trials studying the treatment of HIV Infections.

Emodepside

Emodepside is an anthelmintic drug that is effective against a number of gastrointestinal nematodes, is licensed for use in cats and belongs to the class of drugs known as the…

Emtricitabine

A nucleoside reverse transcriptase inhibitor used for the treatment and prophylaxis of HIV.

Enfuvirtide

An HIV-1 gp41 fusion inhibitor used in patients experiencing HIV-1 replication who are already being treated with other anti-retrovirals.

Enmetazobactam

A beta-lactamase inhibitor used to treat complicated urinary tract infections in combination with cefepime.

Enoxacin

For the treatment of adults (≥18 years of age) with the following infections caused by susceptible strains of the designated microorganisms: (1) uncomplicated urethral or cervical gonorrhea due to Neisseria…

Enrofloxacin

Enrofloxacin is an antibiotic agent from the fluoroquinolone family produced by the Bayer Corporation. Enrofloxacin is approved by the FDA for its veterinary use. Due to the identification of fluoroquinolone-resistant…

Entecavir

A nucleoside analogue used in the treatment of chronic hepatitis B for patients with active viral replication, histological evidence of active disease, or persistent elevations in liver transaminases.

Enviomycin

Cyclic basic peptide related to viomycin. It is isolated from an induced mutant of Streptomyces griseoverticillatus var. tuberacticus and acts as an antitubercular agent with less ototoxicity than tuberactinomycin.

Epicillin

Not Annotated

Eprinomectin

Not Annotated

Ethacridine

Not Annotated

Ethambutol

An antituberculosis agent used in the prophylaxis and treatment of tuberculosis (TB).

Ethanol

For therapeutic neurolysis of nerves or ganglia for the relief of intractable chronic pain in such conditions as inoperable cancer and trigeminal neuralgia (tic douloureux), in patients for whom neurosurgical…

Ethionamide

A second line antitubercular agent used to treat tuberculosis when other treatments have failed.

Etofamide

Etofamide is used as an antiamoebic agent. Etofamide, under the brand name Kitnos, was marketed in Brazil by Pfizer but has been discontinued .

Etravirine

A non-nucleoside reverse transcriptase inhibitor (NNRTI) used in the treatment of HIV-1 infections in combination with other antiretroviral agents.

Eucalyptol

A common ingredient in mouthwash and cosmetics derived naturally from the eucalyptus plant that is frequently used to to improve symptoms of airway mucus hypersecretion.

Eugenol

A phenol used for the temporary relief of toothaches.

Famciclovir

A nucleoside analog DNA polymerase inhibitor used for the treatment of recurrent cold sores and genital herpes in healthy patients and patients with HIV, and to manage herpes zoster.

Favipiravir

An antiviral used to manage influenza, and that has the potential to target other viral infections.

Febantel

Not Annotated

Fenbendazole

Fenbendazole is a benzimidazole that presents a wide spectrum anthelmintic effect. It is used against a number of gastrointestinal parasites including giardia, roundworms, hookworms, whipworms, the Taenia genus of tapeworms,…

Fenticonazole

An imidazole antifungal used to treat a variety of topical fungal infections.

Fiacitabine

Fiacitabine has been used in trials studying the treatment of HIV Infections and Cytomegalovirus Infections.

Fialuridine

Fialuridine is under investigation in clinical trial NCT01337466 (Biodistribution and Dosimetry Evaluation of [124I]FIAU).

Fidaxomicin

A macrolide antibiotic used to treat diarrhea associated with Clostridium difficile infection.

Finafloxacin

Finafloxacin is indicated for the treatment of acute otitis externa (AOE) with or without an otowick, caused by susceptible strains of Pseudomonas aeruginosa and Staphylococcus aureus in patients age 1…

Fleroxacin

Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone.

Florfenicol

Florfenicol is a fluorinated synthetic analog of thiamphenicol.

Flubendazole

Flubendazole is an anthelmintic that is used to treat worm infection in humans. It is available OTC in Europe.

Flucytosine

An antifungal indicated only to treat severe infections throughout the body caused by susceptible strains of Candida or Cryptococcus.

Flumequine

Flumequine is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class used to treat bacterial infections.

Flutrimazole

A topical antifungal used to treat pityriasis capitis and seborrheic dermatitis.

Fomivirsen

Indicated for the local treatment of cytomegalovirus (CMV) retinitis in patients with acquired immunodeficiency syndrome (AIDS), when other therapy has been ineffective or is considered unsuitable [FDA Label, L1428].

Formaldehyde

A naturally occurring hazardous organic compound used as a preservative in animal feed, cosmetic products, laboratory procedures, disinfection, and home building products.

Fosamprenavir

An antiretroviral agent used for the treatment and postexposure prophylaxis of human immunodeficiency virus (HIV-1) infection.

Foscarnet

An antiviral used to treat CMV, HIV, and HSV infections.

Fosfomycin

A broad spectrum antibiotic used to treat uncomplicated urinary tract infections.

Fosmidomycin

Not Available

Fostemsavir

An antiretroviral HIV-1 attachment inhibitor targeted against the gp120 subunit within the HIV-1 gp160 envelope glycoprotein.

Framycetin

An aminoglycoside antibiotic used in various formulations and combinations with other agents to treat hemorrhoids, eye and ear infections, and to reduce nasal carriage of staphylococcus.

Fumagillin

Not Available

Furaltadone

Indicated in combination with other drugs for the treatment of otitis media and externa.

Furazidin

Not Annotated

Furazolidone

A drug for the treatment of infectious diarrhea.

Furvina

Furvina (G1) is an antimicrobial agent active against Gram-positive and Gram-negative bacteria, yeasts, and filamentous fungi. Furvina is marketed in Cuba as Dermofural®, an ointment containing G1 as the only…

Fusafungine

Fusafungine is an antibiotic from Fusarium lateririum, and is used for the treatment of respiratory infections.

Fusidic acid

A topical antibacterial agent used to prevent and treat mild to moderate skin infections caused by susceptible bacteria.

Galidesivir

Galidesivir is an adenosine analogue that has been investigated for use against Zaire Ebolavirus. In animal studies, galidesivir was effective in increasing the survival rates from infections caused by various…

Gamithromycin

Gamithromycin is an antibiotic used in cattle.

Ganciclovir

A DNA polymerase inhibitor used to treat cytomegalovirus and herpetic keratitis of the eye.

Garenoxacin

Investigated for use/treatment in bacterial infection.

Gatifloxacin

A fourth generation fluoroquinolone used to treat a wide variety of infections in the body.

GE-2270A

Not Available

Geldanamycin

Not Available

Gemifloxacin

A quinolone antibacterial agent used for the treatment of acute bacterial exacerbation of chronic bronchitis and mild to moderate community-acquired pneumonia caused by susceptible bacteria.

Geneticin

Geneticin (also known as G418) is an aminoglycoside antibiotic similar in structure to gentamicin B1, produced by Micromonospora rhodorangea. Geneticin blocks polypeptide synthesis by inhibiting the elongation step in both…

Gentian violet cation

An antiseptic violet dye used to prevent various infections, including fungal and bacterial infections.

Gimsilumab

Gimsilumab is under investigation in clinical trial NCT01357759 (Safety and Tolerability of MORAb-022 in Healthy and Rheumatoid Arthritis Subjects).

Glutaral

One of the protein CROSS-LINKING REAGENTS that is used as a disinfectant for sterilization of heat-sensitive equipment and as a laboratory reagent, especially as a fixative.

Glyphosate

Not Available

Gontivimab

Gontivimab is under investigation in clinical trial NCT03468829 (Efficacy and Safety of ALX-0171 in Adult Hematopoietic Stem Cell Transplant (HSCT) Recipients Who Present With Respiratory Syncytial Virus (RSV) Infection).

Gramicidin D

A bactericidal antibiotic used in the treatment of dermatological and ophthalmic infections.

Grazoprevir

An antiviral and NS3/4A protease inhibitor used to treat hepatitis C infections.

Grepafloxacin

A fluoroquinolone antibiotic used to treat various gram positive and gram negative bacterial infections.

Griseofulvin

An antifungal agent used to treat a variety of superficial tinea infections and fungal infections of the fingernails and toes.

GS 0573

Not Annotated

GS-441524

An experimental nucleoside analog antiviral investigated for its use in the treatment of Ebola and SARS-CoV-2 infections.

Hachimycin

Not Annotated

Halofantrine

An antimalarial used for the treatment of severe malaria.

Halofuginone

For the treatment of scleroderma, cancer, and restenosis.

Haloprogin

Used to treat fungal (Tinea) skin infections such as athlete’s foot, jock itch, ringworm, and tinea versicolor.

Hexachlorophene

A chlorinated bisphenol antiseptic used as a surgical scrub and skin cleanser.

Hexamidine

An antiseptic drug used for dermatomycoses and superficial bacterial infections alone or in combination with clotrimazole.

Hexetidine

An topical antiseptic agent used for disinfection and prevention of bacterial, fungal and yeast infections of the oral and vaginal mucosa.

Hexylresorcinol

An ingredient used to relieve irritation, pain, and prevent infection.

HIV Integrase Inhibitor

HIV Integrase Inhibitor is under investigation in clinical trial NCT00397566 (A Multiple Ascending Dose Study of BMS-707035 in HIV-1 Infected Subjects).

Homidium

Homidium is a group II compound with trypanocidal effects.

Honokiol

Honokiol is under investigation in clinical trial NCT00966953 (Development of Clinical Method to Determination Triclosan Retention in Plaque Following Brushing.).

HPA-23

HPA-23 is an investigational antiviral compound.

Human interferon beta

A polypeptide drug used in the treatment of relapsing forms of Multiple Sclerosis (MS).

Hycanthone

Potentially toxic, but effective antischistosomal agent, it is a metabolite of LUCANTHONE. Hycanthone was approved by the FDA in 1975 but is no longer used.

Hydrogen peroxide

A compound used as a disinfectant and sterilizer.

Hydroxychloroquine

An antimalarial medication used to treat uncomplicated cases of malaria and for chemoprophylaxis in specific regions. Also a disease modifying anti-rheumatic drug (DMARD) indicated for treatment of rheumatoid arthritis and lupus erythematosus.

Hydroxytyrosol

Hydroxytyrosol has been used in trials studying the prevention of Breast Cancer.

Hygromycin B

Hygromycin B is an aminoglycoside antibiotic produced by the bacterium Streptomyces hygroscopicus which kills bacteria, fungi and higher eukaryotic cells by inhibiting protein synthesis.

Hypericin

Hypericin is under investigation for the treatment of Cutaneous T-cell Lymphoma.

Hypochlorite

An antimicrobial used to treat and prevent infections of the skin and tissue.

Hypothiocyanite ion

Hypothiocyanite ion is under investigation in clinical trial NCT02598999 (Dose Escalation Study of ALX-009 in Healthy Men and Cystic Fibrosis (CF) and Non-CF Bronchiectasis Patients).

Ibacitabine

Not Annotated

Ibalizumab

A CD4-specific antibody used to treat HIV infections.

Ibrexafungerp

A triterpene antifungal indicated in the treatment of vulvovaginal candidiasis and prevention of recurrent vulvovaginal candidiasis in post-menarchal patients.

Idoxuridine

A pyrimidine analog antiviral used for the treatment of viral eye infections, including herpes simplex keratitis.

Imidocarb

Imidocarb is a urea derivative used in veterinary medicine as an antiprotozoal agent for the treatment of infection with Babesia and other parasites.

Imipenem

A carbapenem antibiotic normally administered with cilastatin to treat a variety of infections.

Indinavir

A protease inhibitor used to treat HIV infection.

Ingavirin

Ingavirin has been used in trials studying the treatment of Influenza and Common Cold.

Inosine pranobex

A medication used to treat subacute sclerosing panencephalitis.

Interferon alfa

An immunomodulator used to treat hepatitis B and C as well as certain types of cancer including cutaneous T-cell lymphoma and renal cell carcinoma.

Interferon alfa-1b

Not Annotated

Interferon alfa-2a

A form of recombinant human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C viruses.

Interferon alfa-2b

A form of recombinant human interferon used to treat hepatitis B and C infection, genital warts, hairy cell leukemia, follicular lymphoma, malignant melanoma, and AIDs-related Kaposi’s sarcoma.

Interferon alfacon-1

A recombinant interferon similar the interferon alfa subtype which is used to treat hepatitis C infections.

Interferon beta-1a

A form of recombinant human interferon used to slow disease progression and reduce the frequency of clinical symptoms in patients who have relapsing multiple sclerosis.

Interferon tau

Not Annotated

Iodine

An ingredient of nutritional supplements that is also used for disinfection.

Isatoic anhydride

Not Available

Isavuconazole

Indicated for patients 18 years of age and older for the treatment of invasive aspergillosis [FDA Label]. Indicated for patients 18 years of age and older for the treatment of…

Isavuconazonium

A triazole antifungal used for the treatment of invasive aspergillosis and mucormycosis.

Isepamicin

Not Annotated

Islatravir

Islatravir is under investigation in clinical trial NCT04233216 (Doravirine/islatravir (DOR/ISL) in Heavily Treatment-experienced (HTE) Participants for Human Immunodeficiency Virus Type 1 (HIV-1) Infection (MK-8591A-019)).

Isoconazole

An imidazole antifungal used for superficial skin and vaginal infections.

Isoniazid

An antibiotic used to treat mycobacterial infections; most commonly use in combination with other antimycobacterial agents for the treatment of active or latent tuberculosis.

Itraconazole

A triazole antifungal agent used to treat various fungal infections, such as blastomycosis and onychomycosis.

Ivermectin

An anti parasite medication used to treat head lice, onchocerciasis, strongyloidiasis, ascariasis, trichuriasis, and enterobiasis.

Josamycin

A macrolide antibiotic used for the treatment of various susceptible bacterial infections.

Ketoconazole

A broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections.

Kitasamycin

Kitasamycin is a macrolide antibiotic derived from Streptomyces kitasatoensis.

Lactoferrin

Lactoferrin is under investigation in clinical trial NCT03748043 (The Effectiveness of Lactoferrin in Treatment of Iron Deficiency Anemia in Children With Chronic Tonsillitis).

Lamivudine

A reverse transcriptase inhibitor used to treat HIV and hepatitis B infections.

Laninamivir

Laninamivir has been used in trials studying the treatment of Influenza.

Laninamivir octanoate

Laninamivir octanoate has been used in trials studying the treatment of Asthma.

Lapachone

Lapachone has been used in trials studying the treatment of Cancer, Carcinoma, Advanced Solid Tumors, Head and Neck Neoplasms, and Carcinoma, Squamous Cell.

Lasalocid

Lasalocid is an agent that presents antibacterial and coccidiostat activities. It is produced by strains of Streptomyces lasaliensis.

Latamoxef

Latamoxef is an oxacephem antibiotic usually grouped with the cephalosporins. It is used to treat bacterial infections. Latamoxef is primarily indicated in conditions like Bone and joint infection, GI infections,…

Lawsone

Not Available

Ledipasvir

A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents.

Lefamulin

A pleuromutilin antibacterial used to treat community-acquired bacterial pneumonia (CABP).

Leronlimab

A humanized monoclonal antibody being investigated

Letermovir

An antiviral medication used for prophylaxis in adult transplant recipients at risk of cytomegalovirus (CMV) infection and disease.

Levamisole

Levamisole is a nicotinic receptor agonist used to treat helminth infections and some skin infections.

Levofloxacin

A fluoroquinolone antibiotic used to treat infections caused by susceptible bacteria of the upper respiratory tract, skin and skin structures, urinary tract, and prostate, as well as for post-exposure treatment of inhaled anthrax and the plague.

Levonadifloxacin

Levonadifloxacin is under investigation in clinical trial NCT03405064 (Comparative Study of Levonadifloxacin (IV and Oral) With Linezolid (IV and Oral) in Acute Bacterial Skin and Skin Structure Infections (ABSSSI)).

LFF-571

LFF571 has been used in trials studying the treatment of Moderate Clostridium Difficile Infection.

Lincomycin

An antibiotic indicated only for the treatment of serious infections and is typically reserved for use in cases of penicillin allergy or where penicillin is inappropriate.

Linezolid

An oxazolidinone antibiotic used to treat infections by susceptible strains of aerobic Gram-positive bacteria.

Lobucavir

Lobucavir has been used in trials studying the treatment of HIV Infections and Cytomegalovirus Infections.

Lomefloxacin

A fluoroquinolone used to prevent and treat a wide variety of infections in the body.

Lonidamine

Investigated for use/treatment in benign prostatic hyperplasia, prostate disorders, and cancer/tumors (unspecified).

Lopinavir

An HIV-1 protease inhibitor used in combination with ritonavir to treat human immunodeficiency virus (HIV) infection.

Loracarbef

Used to treat upper respiratory tract bacterial infections, chronic bronchitis, pneumonia, sinusitis, pharyntitis and tonsillitis, skin absceses, urinary tract infections and pyelonephritis caused by E. coli, S. pyogenes, S. aureus,…

Lucanthone

Intended for use as a radiation sensitizer in the treatment of brain cancer.

Luliconazole

A topical antifungal agent used to treat fungal infections.

Lumefantrine

An antimalarial agent used in combination with artemether for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum.

Lymecycline

A tetracycline antibiotic used for the treatment of acne vulgaris and other susceptible infections.

Lysozyme

An enzyme indicated in the treatment of gastrointestinal disorders in infants, as well as Herpes zoster and Herpes simplex.

Macozinone

Macozinone is under investigation in clinical trial NCT03036163 (Phase 1 Study of PBTZ169).

Maduramicin

Maduramicin is an antiprotozoal agent used in veterinary medicine as prophylaxis against coccidiosis. It is a naturally occurring compound which was first isolated from the actinomycete, Actinomadura rubra.

Mafenide

An antimicrobial topical agent indicated for use as an adjunctive treatment to control bacterial infection when used under moist dressings over meshed autografts on excised burn wounds.

Maftivimab

Part of a product containing three monoclonal IgG1κ antibodies directed against the GP1,2 glycoprotein of Zaire ebolavirus. Together, these three antibodies act to neutralize viral particles and to recruit immune effectors for the destruction of both viral particles and infected cells.

Malachite Green

Not Available

Malacidin A

Malacidin A is being investigated for its antibiotic action and has potential for use as an antibacterial agent in the future .

Malacidin B

Malacidin B is being investigated for its antibiotic action and has potential for use as an antibacterial agent in the future .

Maltotetraose

Not Available

Mandelic acid

Mandelic acid is an approved aromatic, alpha hydroxy acid . Mandelic acid is used as an ingredient in cosmetics and drug products applied topically.

Maraviroc

A CCR5 co-receptor antagonist used with other antiretroviral medications to treat CCR5-tropic HIV-1 infection.

Marbofloxacin

Marbofloxacin is a carboxylic acid, part of the third generation of antibiotic fluoroquinolones. It is used in veterinary medicine. A formulation of marbofloxacin combined with clotrimazole and dexamethasone is available…

Maribavir

A cytomegalovirus (CMV) pUL97 kinase inhibitor used for the treatment of refractory post-transplant CMV infection.

Mebendazole

A benzimidazole anthelmintic used to treat helminth infections.

Meclocycline

A tetracycline antibiotic indicated in the treatment of susceptible skin infections, bacterial vaginitis, vulvovaginitis, and cervicitis.

Mefloquine

An antimalarial agent used in the prophylaxis and treatment of malaria caused by Plasmodium falciparum and Plasmodium vivax.

Meglumine antimoniate

Not Annotated

Melarsoprol

Melarsoprol is under investigation in clinical trial NCT00330148 (Randomized Clinical Trial of Three Drug Combinations for Late-Stage Gambiense Human African Trypanosomiasis).

Mepartricin

A medication indicated in the treatment of benign prostatic hyperplasia, vaginal candidiasis, or trichomoniasis.

Meplazumab

Meplazumab is a humanized anti-CD147 antibody being investigated as an add-on therapy in patients with COVID-19 pneumonia.

Mercuric chloride

Mercury chloride (HgCl2) is a highly toxic compound that volatizes slightly at ordinary temperature and appreciably at 100 degrees C. It is corrosive to mucous membranes and used as a…

Metacycline

For the treatment of acute bacterial exacerbations of chronic bronchitis

Metampicillin

Metampicillin is a penicillin antibiotic prepared by the reaction of ampicillin with formaldehyde. It is hydrolysed in aqueous solution to form ampicillin. Hydrolysis is rapid under acid conditions like the…

Methenamine

A urinary tract antiseptic and antibacterial drug used for the prophylaxis and treatment of frequently recurring urinary tract infections requiring a long-term therapy.

Methylchloroisothiazolinone

Methylchloroisothiazolinone is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years…

Methylisothiazolinone

Not Annotated

Metisazone

Not Annotated

Metrifonate

Metrifonate or trichlorfon is an irreversible organophosphate acetylcholinesterase inhibitor. It is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate.

Metronidazole

A nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections.

Mevastatin

Not used therapeutically due to its many side effects.

Micafungin

An antifungal agent used for the treatment of candidemia, acute disseminated candidiasis, and certain other invasive Candida infections, and for the prophylaxis of Candida infections during stem cell transplantation.

Miconazole

An azole antifungal with broad-spectrum activity used to treat fungal infections affecting the vagina, mouth and skin, including candidiasis.

Micronomicin

Micronomicin is an aminoglycoside antibiotic which is marketed in Japan, and sold under the brand names Sagamicin and Luxomicina.

Midecamycin

A macrolide antibiotic used to treat a variety of infections caused by susceptible bacteria.

Miglustat

A glucosylceramide synthase inhibitor used for the management of mild to moderate type I Gaucher disease for patients who are not candidates for whole enzyme replacement.

Milbemycin oxime

Not Annotated

Miltefosine

An antileishmanial agent used to treat leishmaniasis, a group of disease caused by parasites of the Leishmania type.

Minocycline

A tetracycline analog used to treat a wide variety of infections in the body.

Miocamycin

Miocamycin is a macrolide type antimicrobial . This drug may be marketed in Japan for clinical use as it is listed in the Japanese pharmacopeia . It has shown to…

Misonidazole

Misonidazole is under investigation in clinical trial NCT00038038 (Assessment of Head and Neck Tumor Hypoxia Using 18F-Fluoromisonidazole).

Mizoribine

Mizoribine has been investigated for the treatment of Rheumatoid Arthritis.

Modified vaccinia ankara

A live, non-replicating orthopoxvirus vaccine used to prevent smallpox, monkeypox, and other diseases caused by vaccinia virus.

Molnupiravir

An orally bioavailable isopropylester cytidine analog used to treat COVID-19.

Monensin

Monensin is a polyether isolated from Streptomyces cinnamonensis that presents antibiotic properties. It is widely used in ruminant animal feeds.

Moroxydine

Not Annotated

Moxidectin

Moxidectin is indicated for the treatment of river blindness, also called onchocerciasis, in patients aged 12 years and older. River blindness is caused by a parasitic worm Onchocerca volvulus and…

Moxifloxacin

A fluoroquinolone antibiotic used to treat various bacterial infections.

Mupirocin

An antibacterial ointment used to treat impetigo and secondary skin infections caused by Staphylococcus aureus and Streptococcus pyogenes.

Murepavadin

Murepavadin is under investigation in clinical trial NCT02110459 (Pharmacokinetics and Safety of POL7080 in Patients With Renal Impairment).

Mycophenolate mofetil

An inosine monophosphate dehydrogenase inhibitor used to prevent the rejection of kidney, heart, or liver transplants.

Mycophenolic acid

An immunosuppressant used to prevent organ transplant rejections.

Myxothiazol

Not Available

N-chlorotaurine

Investigated for use/treatment in eye disorders/infections.

N-hydroxyguanidine

Not Available

Nadifloxacin

A topical fluoroquinolone used in the treatment of acne and topical bacterial skin infections.

Nafithromycin

Nafithromycin is under investigation in clinical trial NCT02903836 (Phase II Study of Oral Nafithromycin in CABP).

Naftifine

An antifungal agent used to treat infections of the Tinea, Trichophyton, and Epidermophyton species.

Nalidixic acid

A quinolone antibiotic used to treat urinary tract infections.

Narasin

Narasin is an agent with coccidiostatic and antibacterial properties.

Natamycin

A macrolide antifungal used to treat fungal infections of the eye.

Nebularine

Not Available

Nelfinavir

A viral protease inhibitor used in the treatment of HIV infection.

Nemonoxacin

Investigated for use/treatment in bacterial infection and pneumonia.

Neoarsphenamine

Not Annotated

Netilmicin

An aminoglycoside used to treat a wide variety of infections in the body.

Netivudine

Netivudine has been used in trials studying the treatment of Chickenpox and HIV Infections.

Nevirapine

A non-nucleoside reverse transcriptase inhibitor used as part of a management regimen for HIV-1 virus infection.

Nicarbazin

Not Annotated

Niclosamide

An anthelmintic indicated in the treatment of beef, pork, fish, and dwarf tapeworm infections in adults and children.

Nifuratel

A nitrofuran derivative indicated in the treatment of leucorrhea, vulvovaginal infections, and urinary tract infections.

Nifuroxazide

An antibiotic indicated in the treatment of susceptible gastrointestinal infections.

Nifurtimox

An antiparasitic drug used for the treatment of Chagas disease (Trypanosoma cruzi infection).

Nifurtoinol

Not Annotated

Nigericin

A polyether antibiotic which affects ion transport and ATPase activity in mitochondria. It is produced by Streptomyces hygroscopicus. (From Merck Index, 11th ed)

Nikkomycin Z

Nikkomycin Z has been used in trials studying the treatment and basic science of Coccidioidomycosis.

Nimorazole

Nimorazole has been used in trials studying the treatment of Hypoxia, Radiotherapy, Hypoxic Modification, Gene Profile, Gene Signature, and Head and Neck Squamous Cell Carcinoma, among others.

Niridazole

Not Annotated

Nirmatrelvir

An oral protease inhibitor with emergency use authorization for the treatment of mild-to-moderate COVID-19.

Nisin Z

Nisin Z is under investigation in clinical trial NCT06097468 (Nisin in Oral Cavity Squamous Cell Carcinoma (OCSCC)).

Nitazoxanide

A thiazolide anti-infective used to treat infections by protozoa, helminths, anaerobic bacteria, microaerophilic bacteria, and viruses.

Nitrofural

A topical antibacterial for the prevention and treatment of bacterial infections of the skin.

Nitrofurantoin

An antibiotic used to treat urinary tract infections.

Nitroxoline

Nitroxoline is an antibiotic agent.

Norfloxacin

A broad-spectrum fluoroquinolone antibiotic with variable activity against gram-positive and gram-negative bacteria. Typically reserved for the treatment of UTIs due to accumulation in the urine.

Novobiocin

For the treatment of infections due to staphylococci and other susceptible organisms

Noxytiolin

Local antibacterial that probably acts by releasing formaldehyde in aqueous solutions. It is used for THERAPEUTIC IRRIGATION of infected body cavities – bladder, peritoneum, etc. and as a spray for…

Nystatin

A polyene ionophore antifungal used to treat cutaneous, mucocutaneous, and gastrointestinal mycotic infections, particularly those caused by Candida species.

Octenidine

An antiseptic agent used topically, on mucous membranes, and prior to surgery.

Odalasvir

Odalasvir has been used in trials studying the treatment of Hepatitis C, Chronic and Chronic Hepatitis C Infection.

Odesivimab

Part of a product containing three monoclonal IgG1κ antibodies directed against the GP1,2 glycoprotein of Zaire ebolavirus. Together, these three antibodies act to neutralize viral particles and to recruit immune effectors for the destruction of both viral particles and infected cells.

Ofloxacin

An antibacterial agent used for the treatment of bacterial infections in many parts of the body, including the respiratory tract, kidney, skin, soft tissue, and urinary tract.

Oleandomycin

Oleandomycin is a macrolide antibiotic, though it is less effective than erythromycin. It is synthesized from strains of Streptomyces antibioticus.

Olorofim

Olorofim is under investigation in clinical trial NCT03340597 (Assessment of Varying Oral Dosing Regimens for F901318 in Healthy Subjects).

Oltipraz

Oltipraz has been used in trials studying the treatment and prevention of Lung Cancer, Liver Fibrosis, Liver Cirrhosis, and Non-alcoholic Fatty Liver Disease.

Omoconazole

Not Annotated

Ornidazole

A nitroimidazole agent indicated in the treatment of infections such as trichomoniasis, amebiasis, and giardiasis.

Oseltamivir

A neuraminidase inhibitor used in the prophylaxis and treatment of influenza.

Oseltamivir acid

Not Available

Oxamniquine

For treatment of Schistosomiasis caused by Schistosoma mansoni

Oxantel

An antihelminthic indicated in the treatment of ascaris, trichocephaliasis, and oxyuriasis infections.

Oxfendazole

Oxfendazole is a sulfoxide metabolite of fenbendazole. This benzimidazole antihelminthic protects livestock from roundworm. strongyles, and pinworn.

Oxibendazole

Investigated for use/treatment in infectious and parasitic disease (unspecified) and pediatric indications.

Oxiconazole

A topical antifungal used to treat a variety of dermatophyte infections.

Oxolinic acid

Not Annotated

Oxymatrine

Oxymatrine is under investigation in clinical trial NCT02202473 (Oxymatrine Plus Lamivudine Combination Therapy Versus Lamivudine Monotherapy for Chronic Hepatitis B Infected Subjects).

Oxytetracycline

A tetracycline antibiotic used to treat a wide variety of susceptible bacterial infections.

Ozenoxacin

A quinolone antibiotic used to treat impetigo caused by susceptible bacteria.

p-Coumaric acid

Not Available

Pafuramidine

Investigated for use/treatment in pneumonia, trypanosomiasis, malaria, HIV infection, and infectious and parasitic disease (unspecified).

Palivizumab

A monoclonal anti respiratory syncytial virus F protein antibody used to prevent serious sequelae caused by respiratory syncytial virus infection in pediatric patients.

Palmidrol

A cannabinoid receptor-inactive eCB-related molecule used as prophylactic in helping to prevent respiratory viral infection. Palmidrol is available for human use as a supplement (400 mg capsules) and as food…

Parachlorophenol

An antibacterial agent used to prevent infections in root canals.

Paromomycin

An aminoglycoside antibiotic used in the treatment of acute and chronic intestinal amebiasis, and as an adjunct for the management of hepatic coma.

Pazufloxacin

Pazufloxacin is under investigation in clinical trial NCT02592096 (Pazufloxacin Mesilate Ear Drops Clinical Trial Protocol).

Pefloxacin

An antibiotic used to treat a variety of bacterial infections.

Peginterferon alfa-2a

A modified form of recombinant human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C viruses.

Peginterferon alfa-2b

A purified form of human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C, genital warts, and some cancers.

Penciclovir

A topical nucleoside polymerase inhibitor used in the treatment of recurrent herpes labialis.

Penimepicycline

Penimepicycline is a tetracycline-class antibiotic. It is mentioned on List A produced by the Government of Canada, which is a list of antimicrobial active pharmaceutical ingredients . In the classification…

Pentamidine

An antifungal agent used to treat Pneumocystis pneumonia in patients infected with HIV.

Peracetic acid

A liquid that functions as a strong oxidizing agent. It has an acrid odor and is used as a disinfectant.

Peramivir

An intravenous antiviral agent used to treat acute uncomplicated influenza in patients aged 2 years and older who are shown to be symptomatic for no more than two days.

Pexiganan

Pexiganan is under investigation in clinical trial NCT01594762 (Pexiganan Versus Placebo Control for the Treatment of Mild Infections of Diabetic Foot Ulcers).

PF-232798

PF-232798 is under investigation in clinical trial NCT01140425 (Study To Evaluate The Effect Of A Multiple Oral Dose Of PF-00232798 On QT Intervals In Healthy Subjects).

Phenol

An antiseptic and disinfectant used in a variety of settings.

Phenothiazine

Phenothiazine (PTZ) is an organic thiazine compound.

Phenoxyethanol

An antiseptic used as a hand disinfectant or preservative in medications.

Phenoxymethylpenicillin

A penicillin antibiotic used to prevent and treat mild to moderately severe infections in the respiratory tract, skin, and soft tissues.

Phenylethyl alcohol

An antimicrobial, antiseptic, and disinfectant that is used also as an aromatic essence and preservative in pharmaceutics and perfumery.

Phosphonoacetic Acid

A simple organophosphorus compound that inhibits DNA polymerase, especially in viruses and is used as an antiviral agent. [PubChem]

Phosphoramidon

Not Available

Picloxydine

Not Annotated

Pipemidic acid

A quinolone antibiotic indicated in the treatment of susceptible urinary tract infections.

Piperaquine

For the treatment of uncomplicated Plasmodium falciparum infection in adults, children, and infants aged 6 months and up weighing over 5 kg [FDA Label]. Used in combination with DB11638.

Piperazine

A medication used to treat roundworm and pinworm.

Piromidic acid

Not Annotated

Pivampicillin

An ampicillin prodrug used to treat a variety of infections.

Pivmecillinam

A prodrug of the beta lactam antibiotic mecillinam, indicated for the treatment of uncomplicated urinary tract infections (UTIs).

Platensimycin

Not Available

Pleconaril

Investigated for use/treatment in upper respiratory infection.

Plerixafor

A CXCR4 antagonist used in combination with granulocyte-colony stimulating factor to mobilize hematopoietic stem cells to the peripheral blood for collection and autologous transplantation in patients with non-Hodgkin’s lymphoma and multiple myeloma.

Plumbagin

Plumbagin is a compound investigated for its anticancer activity. It has been found that it inactivates the Akt/NF-kB, MMP-9 and VEGF pathways.

Pocapavir

Not Annotated

Polihexanide

Polihexanide has been used in trials studying the treatment, prevention, and supportive care of Caries, Neoplasm, Skin Diseases, Nail Diseases, and Dental Plaque, among others.

Poloxalene

Ethylene oxide/propylene oxide copolymer is used as a food additive. It belongs to the family of Epoxides. These are compounds containing a cyclic ether with three ring atoms (one oxygen…

Polymyxin B

A polymyxin antibiotic used to treat a wide variety of infections in the body.

Posaconazole

A triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.

Potassium iodate

Not Annotated

Povidone-iodine

A topical antiseptic agent used for the treatment and prevention of infection in wounds.

Pradefovir

Pradefovir is a prodrug of adefovir.

Pradefovir mesylate

Investigated for use as a prodrug for Hepsera in treating hepatitis (viral, B).

Praziquantel

An anthelmintic medication used to treat parasitic worm infections such as schistosomiasis, clonorchiasis, and opisthorchiasis

Primaquine

An antimalarial indicated to prevent relapse of vivax malaria.

Pristinamycin

Not Annotated

Pritelivir

Pritelivir has been used in trials studying the prevention of HSV-2 and Genital Herpes.

Procaine benzylpenicillin

A local anesthetic and antibiotic combination for intramuscular injection to treat a variety of bacterial infections while reducing pain from a deep intramuscular injection.

Proflavine

A topical antiseptic agent used in wound dressings to prevent infections.

Proguanil

A medication indicated for prophylaxis and treatment of Plasmodium falciparum malaria.

Propamidine

Not Annotated

Propanoic acid

An antimicrobial food additive.

Propicillin

Not Annotated

Propiolactone

Propiolactone was used for vaccines, tissue grafts, surgical instruments, and enzymes, as a sterilant of blood plasma, water, milk and nutrient broth as a vapor-phase disinfectant in enclosed spaces. Its…

Protionamide

An antitubercular thioamide-derivative used in the treatment of multi-drug resistant (MDR) tuberculosis and leprosy.

Prulifloxacin

A broad-spectrum fluoroquinolone antibiotic used to treat a variety of susceptible bacterial infections.

Psoralen

Not Annotated

Puromycin

Puromycin is an antibiotic that prevents bacterial protein translation. It is utilized as a selective agent in laboratory cell cultures. Puromycin is toxic to both prokaryotic and eukaryotic cells, resulting…

Pyrantel

An anthelmintic used to treat helminth infections.

Pyrazinamide

An antituberculosis agent used as a component of tuberculosis (TB) treatment.

Pyrimethamine

An antiparasitic drug used in the prevention and treatment of toxoplasmosis and malaria.

Pyrithione

An antimicrobial agent used for the treatment of dandruff and seborrheic dermatitis.

Pyronaridine

A benzonaphthyridine derivative indicated in the treatment of acute malaria caused by P. falciparum or P. vivax in area with low rates of infection and low resistance to artemisinin.

Pyrrolnitrin

Not Annotated

Pyrvinium

An anthelmintic agent used for the treatment of pinworm infestations.

Quinacrine

For the treatment of giardiasis and cutaneous leishmaniasis and the management of malignant effusions.

Quinidine

A medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias.

Quinine

An alkaloid used to treat uncomplicated Plasmodium falciparum malaria.

Quinupristin

An antibiotic agent used in the treatment of serious vancomycin-resistant Enterococcus faecium bacteremia as well as complicated skin and skin structure infections.

R-82913

Not Available

Racivir

Racivir, also known as RCV, is an oxothiolane nucleoside reverse transcriptase inhibitor similar to emtricitabine and lamivudine. Racivir is a 50:50 mixture of emtricitabine and its positive enantiomer. Racivir has…

Radavirsen

Radavirsen is under investigation in clinical trial NCT01375985 (Safety Study of Single Administration Intravenous Treatment for Influenza).

Radezolid

Radezolid has been used in trials studying the treatment of Abscess, Bacterial Skin Diseases, Streptococcal Infections, Infectious Skin Diseases, and Staphylococcal Skin Infections, among others.

Radicicol

Not Available

Raltegravir

An antiretroviral agent used for the treatment of HIV infections in conjunction with other antiretrovirals.

Ramoplanin

For the treatment of bacterial infections.

Remdesivir

A nucleoside analog used to treat RNA virus infections including COVID-19.

Remestemcel-L

Indicated for in the management of acute Graft versus Host Disease (aGvHD) in pediatric patients. Acute GvHD should be refractory to treatment with systemic corticosteroid therapy and/or other immunosuppressive agents….

Resorcinol

Contemporary therapeutic uses for resorcinol primarily revolve around the use of the phenol derivative as an active ingredient in topical antiseptics [L2745, L2744, L40069, F61] or as topical antibacterial skin…

Retapamulin

A topical antibiotic agent used for the treatment of impetigo caused by methicillin-susceptible Staphylococcus aureus or Streptococcus pyogenes.

Rezafungin

An echinocandin antifungal indicated in patients over 18 years old who have limited or no alternative options for the treatment of candidemia and invasive candidiasis.

Ribavirin

A guanosine nucleoside used to treat some forms of Hepatitis C.

Ribavirin monophosphate

Not Annotated

Ribostamycin

A broad spectrum aminoglycoside antibiotic on the list of WHO critical antimicrobials for human medicine.

Ridinilazole

Ridinilazole is under investigation in clinical trial NCT02092935 (A Study of SMT19969 Compared With Vancomycin for the Treatment of Clostridium Difficile-Associated Diarrhoea (CDAD)).

Rifabutin

An antibiotic used to treat mycobacterium avium complex disease in patients with HIV.

Rifalazil

Investigated for use/treatment in atherosclerosis, bacterial infection, and peripheral vascular disease.

Rifampin

An antibiotic used alone or in combination with other antimicrobial drugs to treat tuberculosis and asymptomatic carriers of Neisseria meningitidis.

Rifamycin

An antibacterial used to treat traveler’s diarrhea.

Rifapentine

An antibiotic agent used in the treatment of pulmonary tuberculosis.

Rifaximin

A rifamycin-based non-systemic antibiotic used for the treatment of gastrointestinal bacterial infections, such as traveler’s diarrhea and irritable bowel syndrome, and reduction of overt hepatic encephalopathy recurrence in adults.

Rilpivirine

A non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with other antiretrovirals to specifically treat human immunodeficiency virus type 1 (HIV-1).

Rimantadine

An RNA synthesis inhibitor used to prevent influenza A infection.

Rintatolimod

Not Annotated

Ritonavir

An HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection.

Robenidine

Robenidine is identified as a coccidiostat drug, which slows both the growth and reproductive cycles of coccidian parasites. Robenidine is used to control coccidiosis, a lethal infection in poultry which…

Rolitetracycline

A broad-spectrum tetracycline antibiotic used in cases needing high concentrations or when oral administration is impractical.

Rosoxacin

For the treatment of bacterial infection of respiratory tract, urinary tract, GI, CNS and immuno compromised patients.

Rovafovir etalafenamide

Rovafovir etalafenamide is under investigation in clinical trial NCT03472326 (Efficacy of GS-9131 Functional Monotherapy in HIV-1-Infected Adults Failing a Nucleos(t)Ide Reverse Transcriptase Inhibitor-Containing Regimen).

Roxarsone

Roxarsone is an organoarsenic molecule added to poultry feed. The addition of this compound to poultry feed improves weight gain and feed efficiency as well as prevent the growth of…

Roxithromycin

An antibiotic used to treat a variety of susceptible bacterial infections.

Rupintrivir

Investigated for use/treatment in viral infection.

Ruzasvir

Ruzasvir has been used in trials studying the treatment of Hepatitis C, Hepatitis C, Chronic, and Hepatitis C Infection.

S-Nitrosoglutathione

Not Annotated

Salicylhydroxamic Acid

Not Available

Salicylic acid

An acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts.

Salinomycin

Not Annotated

Santonin

Santonin is a anthelmintic drug that was previously approved in the US to treat certain parasitic infections.

Saquinavir

An HIV protease inhibitor used in combination with other antiretroviral agents for the treatment of HIV-1 with advanced immunodeficiency.

Sarecycline

A tetracycline antibiotic used to treat inflammatory lesions of non-nodular moderate to severe acne vulgaris.

Secnidazole

A nitroimidazole antibiotic used to treat bacterial vaginosis.

Selamectin

Selamectin is a topical parasiticide and antihelminthic used on dogs and cats to treat and prevent infections of heartworms, fleas, ear mites, sarcoptic mange, and certain types of ticks in…

Seliciclib

Investigated for use/treatment in breast cancer, lung cancer, lymphoma (unspecified), multiple myeloma, leukemia (lymphoid), and cancer/tumors (unspecified).

Semzuvolimab

Semzuvolimab is under investigation in clinical trial NCT03149211 (To Investigate the Efficacy and Safety of UB-421 Monotherapy in HIV-1 Infected Adults).

Sertaconazole

A topical antifungal agent used in the treatment of interdigital tinea pedis in immunocompetent patients.

Silver nitrate

Silver nitrate is an inorganic compound with the chemical formula AgNO3. In its solid form, silver nitrate is coordinated in a trigonal planar arrangement. It is often used as a…

Silver oxide

Not Annotated

Silver proteinate

A nasal decongestant and antiseptic of the nasal and ear canals.

Silver sulfadiazine

A topical sulfonamide antibiotic that acts on the bacterial cell wall and cell membrane; approved for the treatment of burns.

Simeprevir

A direct-acting antiviral agent that inhibits HCV NS3/4A protease to treat chronic hepatitis C virus (HCV) infection in adults with HCV genotype 1 or 4.

Sinefungin

Sinefungin is a solid. This compound belongs to the purine nucleosides and analogues. These are compounds comprising a purine base attached to a sugar. The proteins that adenosyl-ornithine target include…

Sirolimus

An mTOR inhibitor immunosuppressant used to prevent organ transplant rejections, treat lymphangioleiomyomatosis, and treat adults with perivascular epithelioid cell tumors.

Sisomicin

Sisomicin has been used in trials studying the treatment of Pyoderma.

Sitafloxacin

A fluoroquinolone antibiotic indicated in the treatment of susceptible bacterial infections.

Sodium bisulfite

An ingredient in parenteral nutrition products for patients with severe liver disorders.

Sodium borate

No FDA- or EMA-approved therapeutic indications on its own.

Sodium stibogluconate

For the treatment of various types of a protozoal infection called leishmaniasis, which may result from sandfly bites in tropical and temperate parts of the world. Also investigated for use/treatment…

Sofosbuvir

A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents.

Solithromycin

Investigated for the treatment of community-acquired pneumonia (CAP).

Sorivudine

Sorivudine has been used in trials studying the treatment of Chickenpox and HIV Infections.

Sotrovimab

A monoclonal antibody for the treatment of mild-to-moderate COVID-19 in patients at increased risk for death or hospitalization.

Sparfloxacin

A fluoroquinolone antibiotic used to treat bacterial respiratory infections and sinusitis.

Sparfosic acid

Sparfosic acid is a solid. This compound belongs to the n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at the terminal nitrogen…

Squalamine

Investigated for use/treatment in ovarian cancer, lung cancer, and macular degeneration.

Stavudine

A dideoxynucleoside used in the treatment of HIV infection.

Stepronin

Strepronin is a mucolytic (expectorant) drug.

Streptolydigin

Streptolydigin is an antibiotic isolated from culture filtrates of Streptomyces lydicus. It is active against gram-postive bacteria except micrococci.

Sulbactam

An beta-lactamase inhibitor antibiotic combined with other antibiotics to treat a variety of susceptible bacterial infections.

Sulbenicillin

Not Annotated

Sulconazole

A topical antifungal agent used for the treatment of tinea cruris, tinea corporis, and tinea versicolor caused by susceptible fungal strains.

Sulfacetamide

A sulfonamide used to treat inflammatory ocular conditions and acne vulgaris.

Sulfachlorpyridazine

A sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine.

Sulfadiazine

A sulfonamide antibiotic used in a variety of infections, such as urinary tract infections, trachoma, and chancroid.

Sulfadicramide

Not Annotated

Sulfadimethoxine

For use in the treatment of infections.

Sulfadoxine

A long acting sulfonamide used for the treatment or prevention of malaria.

Sulfaguanidine

Not Annotated

Sulfaisodimidine

Sulfaisodimidine also called sulfisomidine is an antibacterial product that has been studied for the treatment of urinary tract infections in the 1950s, however, it is unclear whether this drug has…

Sulfamerazine

An antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections.

Sulfameter

Long acting sulfonamide used in leprosy, urinary, and respiratory tract infections.

Sulfamethazine

An antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections.

Sulfamethizole

A sulfonamide antibiotic used to treat a wide variety of susceptible bacterial infections.

Sulfamethoxazole

An oral sulfonamide antibiotic, given in combination with trimethoprim, used to treat a variety of infections of the urinary tract, respiratory system, and gastrointestinal tract.

Sulfamethoxypyridazine

A sulphonamide antibiotic indicated in the treatment of gonorrhea, inflammation, urinary tract ulcers, and bronchitis.

Sulfametopyrazine

An antibiotic used in the treatment or prevention of bacterial infections and malaria.

Sulfamoxole

For the treatment of bacterial infection.

Sulfanilamide

A sulfonamide anti-infective used to treat vulvovaginal candidiasis caused by Candida albicans.

Sulfaphenazole

For the treatment bacterial infections.

Sulfapyridine

A sulfonamide antibiotic used to treat dermatitis herpetiformis, benign mucous membrane pemphigoid and pyoderma gangrenosum.

Sulfaquinoxaline

Sulfaquinoxaline is a veterinary medicine which can be given to cattle and sheep to treat coccidiosis.It is available in Pakistan with Sanna Laboratories in combination with Amprolium and Vitamin K…

Sulfathiazole

Sulfathiazole is effective against a wide range of gram positive and gram negative pathogenic microorganisms. Although no longer used in humans, it is used in cattle.

Sulfisoxazole

A sulfonamide antibiotic used with other antibiotics to prevent and treat a variety of bacterial infections.

Sultamicillin

A mutual prodrug of ampicillin and sulbactam useful in the treatment of infections caused by beta-lactamase-producing bacteria.

Suramin

For treatment of human sleeping sickness, onchocerciasis and other diseases caused by trypanosomes and worms.

Tafenoquine

An antiparasitic agent used for the treatment and prevention of relapse of Vivax malaria.

Talampicillin

Not Annotated

Tanshinone I

Not Annotated

Taribavirin

Investigated for use/treatment in hepatitis (viral, C).

Taurolidine

An antimicrobial derivative of taurine used for prophylaxis of catheter-related infections.

Tavaborole

An antifungal agent used to treat onychomycosis, a fungal infection of the nail.

Tea tree oil

Indicated for topical use to help protect against infection in minor cuts, scrapes, and burns. No FDA-approved therapeutic indications.

Tecovirimat

An antiviral medication used to treat smallpox, monkeypox, and cowpox.

Tedizolid

An oxazolidinone class antibiotic that inhibits bacterial protein synthesis and is proven to be effective in the treatment of certain Gram-positive bacterial infections.

Tedizolid phosphate

An oxazolidinone class antibiotic that inhibits bacterial protein synthesis and is proven to be effective in the treatment of certain Gram-positive bacterial infections.

Telbivudine

A thymidine nucleoside analog used for the treatment of chronic hepatitis B with clinical evidence of viral replication or persistent elevations in serum aminotransferases (ALT or AST).

Telithromycin

An ketolide used to treat community acquired pneumonia of mild to moderate severity.

Temafloxacin

For the treatment of lower respiratory tract infections, genital and urinary infections like prostatitis, and skin infections.

Tenofovir

A nucleotide analog indicated in the treatment of HIV infections.

Tenofovir disoproxil

A nucleotide analog reverse transcriptase inhibitor used in the treatment of Hepatitis B infection and used in the management of HIV-1 infection.

Tenofovir exalidex

Tenofovir exalidex is under investigation in clinical trial NCT01080820 (A Safety, Tolerability and Pharmacokinetic Study of a Single Dose of CMX157 in Healthy Volunteers).

Terbinafine

An allylamine antifungal used to treat dermatophyte infections of toenails and fingernails as well as other fungal skin infections.

Terconazole

An antifungal drug used in the treatment of vulvovaginal candidiasis.

Tetracycline

An antibiotic used to treat a wide variety of susceptible infections.

Tetrandrine

Not Annotated

Tetroxoprim

Not Annotated

Thiabendazole

A benzimidazole used in the treatment of strongyloides, cutaneous larva migrans, visceral larva migrans, and trichinosis infections.

Thiamphenicol

A semisynthetic derivative of chloramphenicol with a broad spectrum of antibacterial activity.

Thiostrepton

Thiostrepton is a natural cyclic oligopeptide antibiotic, derived from several strains of streptomycetes including Streptomyces azureus and Streptomyces laurentii. Thiostrepton is a natural product of the ribosomally synthesized and post-translationally…

Thiosulfuric acid

A sulfur donor used sequentially with sodium nitrite for the reversal of life-threatening acute cyanide poisoning. Also used to reduce the risk of ototoxicity associated with cisplatin.

Thymol

An essential oil found in various over-the-counter antibacterial and antifungal products.

Tiamulin

Tiamulin is a pleuromutilin antibiotic drug that is used in veterinary medicine particularly for pigs and poultry.

Tigecycline

A glycylcycline antibiotic used to treat a number of susceptible bacterial infections.

Tilmicosin

Tilmicosin is a macrolide antibiotic. It is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory disease associated with Mannheimia haemolytica.

Tilorone

Not Annotated

Tinidazole

A nitroimidazole used to treat trichomoniasis, giardiasis, amebiasis, and bacterial vaginosis.

Tioconazole

An imidazole antifungal used to treat vulvovaginal candidiasis.

Tipranavir

A protease inhibitor used to treat HIV-1 resistant to more than 1 protease inhibitor.

Tipranavir C-14

Tipranavir C-14 is under investigation in clinical trial NCT02253797 (Pharmacokinetics of Tipranavir/Ritonavir and Its Metabolites in Healthy Male Subjects).

TJ003234

Not Available

Tolciclate

Not Annotated

Tolnaftate

An antifungal agent used to treat various skin infections caused by fungi.

Tosufloxacin

Not Annotated

Tosylchloramide

A chlorinated disinfectant of the genitals and injured skin.

Triacetin

An acetylating agent indicated in the treatment of ringworm.

Trichostatin A

Not Available

Triclabendazole

An anthelmintic drug used to treat fascioliasis.

Triclocarban

An antibacterial agent used in liquid soaps and body washes.

Triclosan

An antimicrobial agent in clinical setting for disinfection, and prevention of spread and growth of bacteria, fungus, and mildew.

Trifluridine

A nucleoside metabolic inhibitor used to treat keratoconjunctivitis and epithelial keratitis caused by simplex virus, and as a part of chemotherapy for certain types of metastatic gastrointestinal cancers.

Trimethoprim

An antifolate antibiotic often used in combination with sulfamethoxazole to treat a number of infections, including those of the urinary tract, respiratory tract, and gastrointestinal tract.

Trimetrexate

A folate antagonist used for the treatment of moderate-to-severe Pneumocystis carinii pneumonia (PCP) in immunocompromised patients as an alternative therapy in combination with leucovorin.

Troclosene

Not Annotated

Troleandomycin

For the treatment of bacterial infection.

Tromantadine

Tromantadine is marketed as Viru-Merz in the Czech Republic . It is an antiviral used in the treatment of herpes zoster and simplex.

Trovafloxacin

An antibiotic used to treat gonorrhea and chlamydia.

Troxacitabine

Investigated for use/treatment in leukemia (myeloid).

Tulathromycin A

Tulathromycin is a macrolide antibiotic used to treat bovine respiratory disease in cattle and swine respiratory disease in pigs. It is marketed by Pfizer Inc. under the tradename Draxxin.

Tunicamycin

Tunicamycin is a mixture of homologous nucleoside antibiotics that inhibits the UDP-HexNAc: polyprenol-P HexNAc-1-P family of enzymes. One member of this family is the enzyme GlcNAc phosphotransferase (GPT), which catalyzes…

Tylosin

Tylosin is a bacteriostatic macrolide antibiotic and feed additive used in veterinary medicine. It has a broad spectrum of activity against Gram-positive organisms and a limited range of Gram-negative organisms….

Tyrothricin

A topical antibiotic with broad spectrum activity against Gram positive bacteria and some fungal infections.

Ubenimex

An adjuvant therapy used for acute and chronic myelonous leukemia, lung cancer and nasopharyngeal cancer. It is also used to treat hypercholesterolaemia.

UC-781

Investigated for use/treatment in HIV infection.

Ulonivirine

Not Available

Uprifosbuvir

Uprifosbuvir is under investigation in clinical trial NCT02332707 (Efficacy and Safety of Grazoprevir (MK-5172) and Uprifosbuvir (MK-3682) With Elbasvir (MK-8742) or Ruzasvir (MK-8408) for Chronic Hepatitis C Genotype (GT)1 and…

Ursolic acid

Not Annotated

Vaborbactam

A beta lactamase inhibitor used to treat complicated urinary tract infections.

Valaciclovir

An guanine nucleoside antiviral used to treat herpes exacerbations.

Valganciclovir

An antiviral medication used to treat cytomegalovirus (CMV) retinitis in patients diagnosed with acquired immunodeficiency syndrome (AIDS).

Valinomycin

A cyclododecadepsipeptide ionophore antibiotic produced by Streptomyces fulvissimus and related to the enniatins. It is composed of 3 moles each of L-valine, D-alpha-hydroxyisovaleric acid, D-valine, and L-lactic acid linked alternately…

Velpatasvir

A NS5A inhibitor used to treat chronic hepatitis C infections in patients without cirrhosis or with compensated cirrhosis.

Vesatolimod

Vesatolimod has been used in trials studying the treatment of Hepatitis B and Chronic Hepatitis B.

Vesnarinone

Vesnarinone has been used in trials studying the treatment of HIV Infections and Sarcoma, Kaposi.

Vidarabine

An antiviral agent used to treat various viral infections.

Viomycin

Viomycin is an essential component in the drug cocktail currently used to fight infections of Mycobacterium tuberculosis.

Viral Macrophage-Inflammatory Protein

Viral macrophage inflammatory protein-II (vMIP) is a highly basic protein and human chemokine analog encoded by human herpesvirus-8. The structure of vMIP consists of 71 residues and is a monomer…

Virginiamycin

Virginiamycin is a streptogramin antibiotic similar to pristinamycin and quinupristin/dalfopristin. It is a combination of pristinamycin IIA and virginiamycin S1. Virginiamycin is used in the fuel ethanol industry to prevent…

Virginiamycin M1

For the treatment of bacterial infections.

VL-2397

Not Annotated

Voriconazole

A triazole compound used to treat fungal infections.

Wortmannin

Wortmannin is a steroid metabolite of Penicillium funiculosum and Talaromyces wortmannii fungi. This drug acts as a nonspecific, covalent inhibitor of phosphoinositide 3-kinase enzymes (PI3Ks).

Yimitasvir

Not Available

Zalcitabine

A dideoxynucleoside used to treat HIV.

Zanamivir

A neuraminidase inhibitor used to treat influenza A and B.

Zansecimab

Zansecimab is under investigation in clinical trial NCT04342897 (A Study of LY3127804 in Participants With COVID-19).

Zidovudine

A dideoxynucleoside used in the treatment of HIV infection.

Ziresovir

Ziresovir is under investigation in clinical trial NCT03699202 (Anti-RSV Study in Chinese Patients (ASCENT)).

Zoalene

Dinitolmide is a fodder additive for prophylaxis against coccidiosis infections in poultry.