Description: Drugs used to prevent nausea and vomiting
| DRUG | DRUG DESCRIPTION |
|---|---|
| Alizapride | A dopamine antagonist used to prevent nausea and vomiting associated with medical procedures, surgeries, and cancer therapies. |
| Alosetron | A 5-HT3 antagonist used to treat diarrhea-predominant IBS. |
| Amisulpride | A dopamine D2 receptor antagonist used in the treatment of acute and chronic schizophrenia, and in the prevention and treatment of postoperative nausea and vomiting in adults. |
| Aprepitant | A substance P/neurokinin 1 receptor antagonist used to treat nausea and vomiting caused by chemotherapy and surgery. |
| Azasetron | Not Annotated |
| Bromopride | A substituted benzamide, closely related to metoclopramide, used as an antiemetic. |
| Casopitant | Investigated for use/treatment in urinary incontinence and adverse effects (chemotherapy). |
| Chlorpromazine | A phenothiazine antipsychotic used to treat nausea, vomiting, preoperative anxiety, schizophrenia, bipolar disorder, and severe behavioral problems in children. |
| Clebopride | A dopamine antagonist used to treat symptoms associated with functional gastrointestinal disorders. Clebopride may also be used to treat nausea and vomiting associated with chemotherapy. |
| Cyclizine | An antihistamine and antiemetic drug used for the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness, and vertigo. |
| Dexamethasone | A glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders. |
| Dexanabinol | Investigated for use/treatment in traumatic brain injuries and neurologic disorders. |
| Dimenhydrinate | A medication used to prevent and treat nausea, vomiting, vertigo, and motion sickness. |
| Diphenhydramine | A H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria, insect bites/stings, and allergic rashes. |
| Diphenidol | An antiemetic agent used for the prevention and symptomatic treatment of nausea and vomiting associated with various conditions as Meniere’s disease and surgery of the middle and inner ear. |
| Dixyrazine | Not Annotated |
| Dolasetron | An antinauseant and antiemetic used in chemotherapy and postoperatively. |
| Domperidone | A dopamine receptor antagonist used as a peristaltic stimulant and anti-emetic agent for dyspepsia, indigestion, epigastric pain, nausea, and vomiting. |
| Doxylamine | An antihistamine used to treat insomnia and allergy symptoms and is used with pyridoxine in the treatment of nausea and vomiting in pregnancy. |
| Droperidol | A butyrophenone derivative and dopamine antagonist used to prevent and treat postoperative nausea and vomiting. |
| Fosaprepitant | An antiemetic drug used in combination with other antiemetic agents for the prevention of acute and delayed nausea and vomiting caused by chemotherapy. |
| Granisetron | A 5HT3 antagonist used to treat nausea and vomiting in cancer therapy and postoperatively. |
| Haloperidol | An antipsychotic agent used to treat schizophrenia and other psychoses, as well as symptoms of agitation, irritability, and delirium. |
| Lorazepam | A short-acting benzodiazepine commonly used to treat panic disorders, severe anxiety, and seizures. |
| Maropitant | Maropitant, used as maropitant citrate, is a neurokinin receptor antagonist, which was developed by Zoetis specifically for the treatment of motion sickness and vomiting in dogs. It was approved by… |
| Meclizine | A histamine H1 antagonist used to treat nausea, vomiting, and dizziness associated with motion sickness. |
| Methylprednisolone | A corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases. |
| Metoclopramide | An antiemetic agent and dopamine D2 antagonist used in the treatment of gastroesophageal reflux disease, prevention of nausea and vomiting, and to stimulate gastric emptying. |
| Metopimazine | Not Annotated |
| Nabilone | A synthetic delta-9-THC used in the treatment of anorexia and weight loss in HIV patients as well as nausea and vomiting in cancer chemotherapy. |
| Olanzapine | An antipsychotic drug used in the management of schizophrenia, bipolar 1 disorder, and agitation associated with these disorders. |
| Ondansetron | A serotonin 5-HT3 receptor antagonist used to prevent nausea and vomiting in cancer chemotherapy and postoperatively. |
| Palonosetron | A serotonin antagonist used in the prophylaxis or management of vomiting that results from emetogenic chemotherapy, and for the management of postoperative nausea and vomiting. |
| Peppermint oil | An ingredient used in a variety of natural health products and is not an approved medication. |
| Prochlorperazine | A phenothiazine derivative used in the treatment of schizophrenia and anxiety and to relieve severe nausea and vomiting. |
| Promazine | A phenothiazine used to manage schizophrenia. |
| Ramosetron | A selective 5-HT3 antagonist used as an antiemetic for chemotherapy- and postoperative-associated nausea and vomiting. It may also possess efficacy in irritable bowel syndrome. |
| Scopolamine | A belladonna alkaloid with anticholinergic effects indicated for the treatment of nausea and vomiting associated with motion sickness and postoperative nausea and vomiting (PONV). |
| Thiethylperazine | A drug used for the treatment of nausea and vomiting. |
| Trifluoperazine | A phenothiazine used to treat depression, anxiety, and agitation. |
| Triflupromazine | Used mainly in the management of psychoses. Also used to control nausea and vomiting. |
| Trimethobenzamide | An antiemetic used to treat postoperative nausea and vomiting and nausea associated with gastroenteritis. |
| Tropisetron | A 5HT-3 receptor antagonist used as an antiemetic in the treatment of chemotherapy-induced nausea and vomiting. |
| Vofopitant | Vofopitant has been used in trials studying the treatment of PTSD, Primary Insomnia, and Sleep Initiation and Maintenance Disorders. |