Premenopausal: Refers to women who still have active ovarian function and produce estrogen and progesterone.
- Oncology relevance:
- Influences breast cancer risk and biology.
- Determines endocrine therapy choice: e.g., tamoxifen or ovarian suppression + aromatase inhibitor rather than aromatase inhibitor alone.
- Pharmacist note: Premenopausal status is critical for dosing decisions, drug selection, and predicting endocrine therapy efficacy.