IHC (ImmunoHistoChemistry) is a laboratory technique used to detect specific antigens (proteins) in tissue samples by using antibodies that bind to them, followed by a visualization method (such as chromogenic staining or fluorescence).
In oncology, it’s commonly used to:
- Classify tumors (e.g., breast cancer subtypes via ER, PR, HER2 status)
- Guide treatment decisions (e.g., targeted therapy eligibility)
- Predict prognosis