| Aclidinium | An inhaled long-acting anticholinergic used as a maintenance bronchodilator in patients with chronic obstructive pulmonary disease (COPD). |
| Adiphenine | Not Annotated |
| Agmatine | Agmatine is being studied experimentally for several indications such as cardioprotection, diabetes, decreased kidney function, neuroprotection (stroke, severe CNS injuries, epilepsy, glaucoma, and neuropathic pain), and psychiatric conditions (depression, anxiety,… |
| Alcuronium | A non-depolarizing skeletal muscle relaxant similar to tubocurarine. It is used as an anesthesia adjuvant. |
| Amantadine | A medication used to treat dyskinesia in Parkinson’s patients receiving levodopa, as well as extrapyramidal side effects of medications. |
| Amitriptyline | A tricyclic antidepressant indicated in the treatment of depressive illness, either endogenous or psychotic, and to relieve depression associated anxiety. |
| Amobarbital | A barbiturate derivative used for the induction of sedation during procedures, short-term management of insomnia, and acute management of refractory tonic-clonic seizures. |
| Amoxapine | A tricyclic antidepressant used in the treatment of neurotic or reactive depressive disorders and endogenous or psychotic depression. |
| Anisotropine methylbromide | For use in conjunction with antacids or histamine H2-receptor antagonists in the treatment of peptic ulcer, to reduce further gastric acid secretion and delay gastric emptying. |
| Aprobarbital | Aprobarbital is a barbiturate derivative synthesized in the 1920s by Ernst Preiswerk. It was determined that the substance was capable of demonstrating sedative, hypnotic, and anticonvulsant effects. A primary treatment… |
| Aripiprazole | An atypical antipsychotic used in the treatment of a wide variety of mood and psychotic disorders, such as schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette’s syndrome. |
| Atracurium | A neuromuscular blocker indicated to relax muscles during mechanical ventilation under general anesthesia or intubation. |
| Atracurium besylate | A non-depolarizing neuromuscular blocker used to facilitate endotracheal intubation and relax skeletal muscles during surgery. |
| Atropine | A muscarinic antagonist used to treat poisoning by muscarinic agents, including organophosphates and other drugs. |
| Azatadine | An H1 receptor antagonist used to treat perennial and allergic rhinitis as well as eustachian tube congestion. |
| Barbital | A long-acting barbiturate that depresses most metabolic processes at high doses. It is used as a hypnotic and sedative and may induce dependence. Barbital is also used in veterinary practice… |
| Batefenterol | Batefenterol has been used in trials studying the treatment of Pulmonary Disease, Chronic Obstructive. |
| Belladonna | No therapeutic indications. |
| Benactyzine | Benactyzine is an anticholinergic drug used as an antidepressant in the treatment of depression and associated anxiety. Benactyzine is no longer widely used in medicine, although it is still a… |
| Benzatropine | An anticholinergic drug used to treat Parkinson’s disease (PD) and extrapyramidal symptoms, except tardive dyskinesia. |
| Benzilone | Not Annotated |
| Benzquinamide | Used to prevent and treat nausea and vomiting associated with anesthesia and surgery, administered intramuscularly or intravenously. |
| Bevonium | Not Annotated |
| Biperiden | A muscarinic receptor antagonist used to treat parkinsonism and control extrapyramidal side effects of neuroleptic drugs. |
| Bornaprine | An anticholinergic drug indicated in the treatment of hyperhidrosis, dyskinesia, akathisia, parkinsonism, and Parkinson’s disease. |
| Brompheniramine | A histamine H1 antagonist used to treat coughs, upper respiratory symptoms, and nasal congestion associated with allergies and the common cold. |
| Buclizine | An antihistamine and antiemetic drug for the treatment of allergy symptoms and prevention of nausea and vomiting. |
| Butabarbital | A barbiturate drug used as a sedative and hypnotic. |
| Butalbital | A barbiturate drug used for symptomatic treatment of tension-type headache in various combinations with acetaminophen, aspirin, caffeine, and codeine. |
| Butobarbital | For the treatment of insomnia. |
| Butylscopolamine | An antispasmodic and anticholinergic agent used for the symptomatic treatment of abdominal cramping and pain. |
| Camylofin | Not Annotated |
| Chlorphenoxamine | An antihistamine used as an antipruritic. |
| Chlorpromazine | A phenothiazine antipsychotic used to treat nausea, vomiting, preoperative anxiety, schizophrenia, bipolar disorder, and severe behavioral problems in children. |
| Chlorprothixene | A thioxanthene antipsychotic. |
| Cisatracurium | A skeletal muscle relaxant used to facilitate tracheal intubation, muscle relaxation in surgery, or mechanical ventilation. |
| Clidinium | A synthetic anticholinergic used to treat peptic ulcer disease, colicky abdominal pain, diverticulitis, and IBS. |
| Clozapine | An atypical or second-generation antipsychotic drug used in treatment-resistant schizophrenia and to decrease suicide risk in schizophrenic patients. |
| Cocaine | An ester local anesthetic used during diagnostic procedures and surgeries in or through the nasal cavities. |
| Cyclopentolate | An anticholinergic used to cause mydriasis and cycloplegia for diagnostic testing. |
| Cycrimine | For treatment and management of Parkinson’s disease. |
| Cyproheptadine | A combined serotonin and histamine antagonist used in the treatment of allergic symptoms, for appetite stimulation, and off-label in the treatment of serotonin syndrome. |
| Darifenacin | An M3 muscarinic receptor blocker used to treat urinary incontinence. |
| Desipramine | A tricyclic antidepressant used in the treatment of depression. |
| Desloratadine | A second generation tricyclic antihistamine used to treat seasonal and non seasonal allergic rhinitis, pruritus, and urticaria. |
| Dexetimide | A muscarinic antagonist that has been used to treat neuroleptic-induced parkinsonism. Benzetimide is the (-)-enantimorph of dexetimide. |
| Dextromethorphan | An NMDA receptor antagonist used to treat cases of dry cough. |
| Dicyclomine | An antimuscarinic agent used to treat IBS. |
| Difemerine | Not Annotated |
| Dihexyverine | Not Annotated |
| Dihydro-2-thioxo-5-((5-(2-(trifluoromethyl)phenyl)-2-furanyl)methyl)-4,6(1H,5H)-pyrimidinedione | Not Available |
| Dimetindene | A 1st generation selective H1 antagonist used topically as an antipruritic and orally to treat allergies. |
| Diphemanil | Used in the treatment of peptic ulcer, gastric hyperacidity, and hypermotility in gastritis and pylorospasm, and in the treatment of hyperhidrosis (excessive perspiration). |
| Diphenhydramine | A H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria, insect bites/stings, and allergic rashes. |
| Diphenidol | An antiemetic agent used for the prevention and symptomatic treatment of nausea and vomiting associated with various conditions as Meniere’s disease and surgery of the middle and inner ear. |
| Disopyramide | A class 1A antiarrhythmic agent used to treat life-threatening ventricular arrhythmias. |
| Dosulepin | A tricyclic antidepressant commonly used only in patients for whom alternative therapies are ineffective due to its toxicity potential. |
| Doxacurium | A nondepolarizing neuromuscular blocking agent used as an adjunct to general anesthesia to facilitate tracheal intubation, and to provide skeletal muscle relaxation during surgical procedures. |
| Doxepin | A psychotropic agent used for the treatment of depression, anxiety, manic-depressive disorder, and insomnia. |
| Doxylamine | An antihistamine used to treat insomnia and allergy symptoms and is used with pyridoxine in the treatment of nausea and vomiting in pregnancy. |
| Emepronium | Not Annotated |
| Emetonium iodide | Not Annotated |
| Escitalopram | A selective serotonin re-uptake inhibitor used in the treatment of major depressive disorder (MDD), generalized anxiety disorder (GAD), and other select psychiatric disorders such as obsessive-compulsive disorder (OCD). |
| Etanautine | Not Annotated |
| Etybenzatropine | Not Annotated |
| Fenoterol | A beta-2 adrenergic agonist and bronchodilator used for the symptomatic treatment of asthma. |
| Fenpiverinium | An anticholinergic agent indicated in the treatment of smooth muscle spasms. |
| Fesoterodine | An antimuscarinic agent used in the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency. |
| Flavoxate | A muscarinic antagonist and spasmolytic used for the symptomatic relief of conditions associated with lack of muscle control in the bladder, such as dysuria, urgency, and nocturia. |
| Fluoxetine | A selective serotonin reuptake inhibitor used to treat major depressive disorder, bulimia, OCD, premenstrual dysphoric disorder, panic disorder, and bipolar I. |
| Flupentixol | A thioxanthene neuroleptic used to treat schizophrenia and depression. |
| Gallamine | Not Annotated |
| Gallamine triethiodide | A nondepolarizing nerve blocker used in addition to anesthesia to cause skeletal muscle relaxation. |
| Gantacurium | Investigated for use/treatment in anesthesia (unspecified). |
| Glycopyrronium | An anticholinergic agent used to treat hyperhidrosis, severe drooling, COPD, used with other medications to treat ulcers, and used in anesthesia. |
| Heptabarbital | Used mainly for sedation and hypnosis. |
| Hexafluronium | Used as an adjunct with succinylcholine (or suxamethonium chloride) to prolong muscle relaxation and to prevent succinylcholine-induced muscle fasciculations. |
| Hexamethonium | A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been… |
| Hexobarbital | For the induction of anesthesia prior to the use of other general anesthetic agents and for induction of anesthesia for short surgical, diagnostic, or therapeutic procedures associated with minimal painful… |
| Hexocyclium | The World Health Organization classifies hexocyclium as a drug for functional gastrointestinal disorders . Like other anti-muscarinic agents, hexocyclium was likely used to treat peptic ulcers or diarrhea. |
| Homatropine | An anticholinergic agent used to dilate the pupil, treat inflammation of the uveal tract, and suppress a cough. |
| Homatropine methylbromide | A muscarinic receptor antagonist used to treat peptic ulcers, gastric ulcers, and duodenal ulcers. |
| Homidium | Homidium is a group II compound with trypanocidal effects. |
| Hyoscyamine | An anticholinergic indicated to treat functional gastrointestinal disorders, biliary and renal colic, and acute rhinitis. |
| Imidafenacin | An antispasmodic with anticholinergic effects used to reduce urinary frequency. |
| Imipramine | A tricyclic antidepressant indicated for the treatment of depression and to reduce childhood enuresis. |
| Ipratropium | An anticholinergic drug used in the control of symptoms related to bronchospasm in chronic obstructive pulmonary disease (COPD). |
| Isoflurane | An inhaled general anesthetic used in surgery. |
| Isopropamide | A long-acting anticholinergic drug used to relieve symptoms of spastic and painful symptoms of gastrointestinal conditions and symptoms of flu, colds, and related conditions. |
| Lamotrigine | A phenyltriazine antiepileptic used to treat some types of epilepsy and bipolar I disorder. |
| Levacetylmethadol | For the treatment and management of opiate dependence. It is sometimes used to treat severe pain in terminal patients. |
| Maprotiline | A tetracyclic antidepressant used to treat depressive illness, major depressive disorder, bipolar disorder, and anxiety associated with depression. |
| Mazaticol | Not Annotated |
| Mebeverine | An antispasmodic used for the symptomatic treatment of stomach pain and spasms associated with irritable bowel syndrome and other gastrointestinal illnesses. |
| Mecamylamine | A nicotine antagonist used to treat moderate to severe essential hypertension and uncomplicated malignant hypertension. |
| Meclizine | A histamine H1 antagonist used to treat nausea, vomiting, and dizziness associated with motion sickness. |
| Mepenzolate | A postganglionic parasympathetic inhibitor that was previously approved for improving the healing of gastric ulcers, but has been discontinued. |
| Methadone | An opioid analgesic indicated for management of severe pain that is not responsive to alternative treatments. Also used to aid in detoxification and maintenance treatment of opioid addiction. |
| Methantheline | For the treatment of peptic ulcer disease, irritable bowel syndrome, pancreatitis, gastritis, biliary dyskinesia, pylorosplasm, and reflex neurogenic bladder in children. |
| Metharbital | Metharbital is used for the treatment of epilepsy. |
| Methotrimeprazine | A phenothiazine used in the management of psychosis, particular those of schizophrenia, and manic phases of bipolar disorder. |
| Methscopolamine | Methscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products. The… |
| Methscopolamine bromide | A muscarinic antagonist used to treat peptic ulcers, nausea, vomiting, and motion sickness. |
| Methylphenobarbital | For the relief of anxiety, tension, and apprehension, also used as an anticonvulsant for the treatment of epilepsy. |
| Metixene | Used for the symptomatic treatment of parkinsonism. |
| Metocurine | Metocurine is a muscle relaxant. |
| Metocurine iodide | For use as an anesthesia adjunct to induce skeletal muscle relaxation and to reduce the intensity of muscle contractions in convulsive therapy. |
| Mivacurium | A short-acting non-depolarizing neuromuscular blocking agent used to induce anesthesia during intubation and promote skeletal muscle relaxation during surgery or mechanical ventilation. |
| Nicardipine | A calcium channel blocker used for the short-term treatment of hypertension and chronic stable angina. |
| Nortriptyline | A tricyclic antidepressant used in the treatment of depression. |
| Olanzapine | An antipsychotic drug used in the management of schizophrenia, bipolar 1 disorder, and agitation associated with these disorders. |
| Orphenadrine | A muscarinic antagonist used as an adjunct for the symptomatic relief of musculoskeletal pain and discomfort. |
| Otilonium | A spasmolytic medication used to treat irritable bowel syndrome (IBS). |
| Oxitropium | Oxitropium has been investigated for the treatment of Pulmonary Disease, Chronic Obstructive. |
| Oxybutynin | An antimuscarinic agent that reduces detrusor muscle activity, relaxing the bladder and preventing the urge to void. |
| Oxyphencyclimine | A drug used to treat smooth muscle spasticity. |
| Oxyphenonium | For the treatment of visceral spasms |
| Pancuronium | A neuromuscular blocker used as an adjunct to general anesthesia to facilitate tracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. |
| Paroxetine | A selective serotonin reuptake inhibitor used to treat major depressive disorder, panic disorder, OCD, social phobia, generalized anxiety disorder, the vasomotor symptoms of menopause, and premenstrual dysphoric disorder. |
| Penthienate | Not Annotated |
| Pentobarbital | A barbiturate drug used to induce sleep, cause sedation, and control certain types of seizures. |
| Pentolinium | Used to produce controlled hypotension during surgical procedures and in hypertensive crises. |
| Phenglutarimide | Not Annotated |
| Phenobarbital | A long-lasting barbiturate and anticonvulsant used in the treatment of all types of seizures, except for absent seizures. |
| Pipecuronium | A nondepolarizing neuromuscular blocking agent used to relax muscles during anesthesia and surgical procedures. |
| Pipenzolate | An antimuscarinic agent indicated in the treatment of gastrointestinal motility disorders and arrhythmia. |
| Piperidolate | Not Annotated |
| Pirenzepine | An antimuscarinic agent used to treat peptic ulcers, gastric ulcers, and duodenal ulcers. |
| Pizotifen | A serotonin and tryptamine antagonist indicated for migraine prophylaxis. |
| Poldine | Not Annotated |
| Prifinium | Prifinium is an antimuscarinic agent with antispasmodic and antiemetic properties. It may be useful for the treatment of irritable bowel syndrome . |
| Primidone | An antiepileptic used to treat grand mal, psychomotor, and focal epileptic seizures. |
| Procaine | A local anesthetic used for anesthesia, peripheral nerve block, and spinal nerve block. |
| Procyclidine | An antispasmodic drug used to treat parkinsonism of various types and in the treatment of extrapyramidal symptoms. |
| Profenamine | An antidyskinetic phenothiazine used to treat the symptoms of Parkinson’s disease. |
| Promazine | A phenothiazine used to manage schizophrenia. |
| Promethazine | A first-generation antihistamine used for the treatment of allergic conditions, nausea and vomiting, and motion sickness. |
| Propantheline | An antimuscarinic agent used to treat urinary incontinence, hyperhidrosis, as well as cramps and spasms of the stomach, intestines, and bladder. |
| Propiomazine | Propiomazine is largely used for its antihistamininc sleep inducing effects in treating insomnia. |
| Propiverine | An antimuscarinic agent used to treat urinary incontinence or increased urinary frequency or urgency. |
| Quetiapine | A psychotropic agent used for the management of bipolar disorder, schizophrenia, and major depressive disorder. |
| Quinidine | A medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias. |
| Rapacuronium | A nondepolarizing neuromuscular blocking agent used as an adjunct to general anesthesia to facilitate tracheal intubation, and to provide skeletal muscle relaxation during surgical procedures. |
| Revefenacin | An anticholinergic agent used to treat COPD. |
| Rociverine | An antispasmodic indicated in the treatment of urinary, gastrointestinal, and biliary tract spasms. |
| Rocuronium | A vecuronium analog used to facilitate tracheal intubation and to relax skeletal muscles during surgery. |
| Scopolamine | A belladonna alkaloid with anticholinergic effects indicated for the treatment of nausea and vomiting associated with motion sickness and postoperative nausea and vomiting (PONV). |
| Secobarbital | A barbiturate used for the short-term treatment of insomnia. |
| Solifenacin | A muscarinic antagonist with antispasmodic properties used to treat urge urinary incontinence, urgency, and urinary frequency associated with an overactive bladder. |
| Talbutal | For use as a sedative and hypnotic. |
| Terfenadine | An antihistamine for the treatment of allergy symptoms. |
| Thiopental | A barbiturate used to induce general anesthesia, treat convulsions, and reduce intracranial pressure. |
| Thonzylamine | Thozylamine is indicated for use in the symptomatic control of allergic rhinitis or other upper respiratory allergic symptoms [FDA Label]. It is typically a part of combination over the counter… |
| Tiemonium iodide | Not Annotated |
| Timepidium | Not Annotated |
| Tiotropium | A long-acting bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). |
| Tolterodine | A muscarinic receptor antagonist used to treat overactive bladder with urinary incontinence, urgency, and frequency. |
| Tramadol | A centrally-acting opioid agonist and SNRI (serotonin/norepinephrine reuptake inhibitor) used for the management of moderate to severe pain in adults. |
| Tridihexethyl | Used as an adjunct in the treatment of peptic ulcer disease and in Acquired nystagmus |
| Triflupromazine | Used mainly in the management of psychoses. Also used to control nausea and vomiting. |
| Trihexyphenidyl | An antispasmodic drug used as an adjunct drug in the management of parkinsonism and as a treatment for extrapyramidal symptoms caused by drugs affecting the central nervous system (CNS). |
| Trimebutine | A spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and treatment of postoperative paralytic ileus following abdominal surgery. |
| Trimethaphan | For the controlled reduction of blood pressure during surgery and in the treatment of hypertensive emergencies. |
| Tropatepine | Tropatepine has been used in France for its antiparkinsons activities . |
| Tropicamide | A muscarinic receptor antagonist used to induce mydriasis and cycloplegia for diagnostic procedures. |
| Trospium | An antimuscarinic agent used to treat the symptoms of overactive bladder (OAB). |
| Tubocurarine | Tubocurarine is a non-depolarizing neuromuscular blocking agent and the first identified curare alkaloid. Curare is one of the names used to describe plant-derived poisons used by indigenous South Americans to… |
| Umeclidinium | A long-acting muscarinic antagonist used as a long-term maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD). |
| Vecuronium | A nondepolarizing neuromuscular blocking agent used to relax muscles or as an adjunct in general anesthesia during surgical procedures. |
| Viloxazine | A selective norepinephrine reuptake inhibitor indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in adults in children. |
| Ziprasidone | An atypical antipsychotic used to manage schizophrenia, bipolar mania, and agitation in patients with schizophrenia. |