Drugs for Constipation
| Drug | Description |
| Alvimopan | An opioid antagonist used to reduce healing time of the upper and lower gastrointestinal tract following surgical procedures that involve bowel resection with primary anastomosis. |
| Bisacodyl | A stimulant laxative used for the temporary relief of occasional constipation and cleansing of the colon as a preparation for colonoscopy in adults. |
| Bisoxatin | For use in the treatment of constipation in the absence of bowel obstruction and for surgical preparation of the colon . |
| Calcium polycarbophil | A bulk forming laxative used to treat constipation. |
| Castor oil | An ingredient used in a variety of natural health products. |
| Dantron | A drug used to relieve acute and chronic inflammation of the oral cavity and oropharynx. |
| Docusate | A medication used to treat constipation associated with dry, hard stools, or opioid induced constipation. |
| Elobixibat | Elobixibat has been used in trials studying the treatment and basic science of Dyslipidemia, Constipation, Chronic Constipation, Functional Constipation, and Chronic Idiopathic Constipation. |
| Glycerin | It is used as a solvent, emollient, pharmaceutical agent, and sweetening agent. |
| Karaya gum | An extract from Karaya gum used in allergy testing. |
| Lactitol | An orally administered osmotic laxative used to treat chronic idiopathic constipation. |
| Lactulose | A disaccharide derivative of lactose used to treat constipation and portal systemic encephalopathy. |
| Linaclotide | A guanylate cyclase-C agonist used to treat different types of constipation, such as irritable bowel syndrome-related constipation, idiopathic constipation, and functional constipation. |
| Lubiprostone | A prostaglandin derivative used to treat constipation caused by irritable bowel syndrome and opioid-use. |
| Magnesium carbonate | An antacid used for symptomatic relief of heartburn, indigestion, and upset stomach. |
| Magnesium citrate | A laxative used in bowel preparation for colonoscopy or as a magnesium supplement. |
| Magnesium oxide | A compound commonly used as a laxative for the symptomatic relief of acid indigestion and upset stomach, and in health supplements for cardiovascular and neuromuscular health. |
| Magnesium peroxide | Not Annotated |
| Magnesium sulfate | A drug used to treat convulsions during pregnancy, nephritis in children, magnesium deficiency, and tetany. |
| Mannitol | A sugar alcohol used to test for asthma, to reduce intracranial and intraocular pressure, to measure glomerular filtration rate, and to manage pulmonary symptoms associated with cystic fibrosis. |
| Methylcellulose | A compound used as a bulk forming laxative and is not an approved medication. |
| Methylnaltrexone | A μ-opioid antagonist used for the treatment of opioid-induced constipation in palliative patients that are inadequately responding to laxative therapy. |
| Mineral oil | Mineral oil is not considered an active pharmacological ingredient in pharmaceutical preparations and so has no official indication. It is typically present in topical formulations as an emollient and occlusive… |
| Naldemedine | An opioid antagonist used to to treat opioid-induced constipation. |
| Naloxegol | A peripherally-selective opioid antagonist used to treat opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain. |
| Naloxone | An opioid receptor antagonist used to rapidly reverse an opioid overdose. Also included in some drug formulations as an abuse deterrent to prevent injection. |
| Oxyphenisatin | A laxative that undergoes enterohepatic circulation. It may cause jaundice. |
| Pentaerithrityl | Not Annotated |
| Phenolphthalein | A drug used for symptomatic relief of constipation and bowel cleansing prior to medical procedures. |
| Picosulfuric acid | A stimulant laxative used for cleansing of the colon as a preparation for colonoscopy in adults. |
| Plantago ovata seed | A plant extract indicated in the treatment of occasional constipation. |
| Plecanatide | A laxative used to treat chronic idiopathic constipation and IBS with constipation. |
| Polyethylene glycol | A laxative used to treat constipation and used for bowel preparation before colonoscopies and other procedures. |
| Prucalopride | A 5-HT4 receptor agonist indicated to treat adults with chronic idiopathic constipation. |
| Sennosides | A laxative used to treat constipation. |
| Sodium lauryl sulfoacetate | A laxative indicated in the treatment of constipation and bowel preparation for rectal endoscopy. |
| Sodium phosphate, monobasic | A source of phosphorus used prevent or correct hypophosphatemia in patients with restricted or no oral intake. |
| Sodium sulfate | An agent used for bowel cleansing prior to colonoscopy or barium enema X-ray examination. |
| Sodium tartrate | It acts as an emulsifier and pH control agent in food products , . In the laboratory, it is used while performing the Karl Fischer equation, which is used to… |
| Sorbitol | A product that can be used as a laxative to relieve constipation, and also as a urologic irrigating fluid. May also be used as a pharmaceutical sweetener. |
| Tegaserod | A serotonin-4 (5-HT4) receptor agonist indicated for the treatment of constipation predominant irritable bowel syndrome (IBS-C) specifically in women under the age of 65. There is currently no safety or efficacy data for use of tegaserol in men. |
| Tenapanor | An NHE3 inhibitor indicated for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic kidney disease, |